Discovery

In July 2024 a startling scientific paper was published. Headlined ‘Evidence of dark oxygen production at the abyssal seafloor’, scientists told how they had discovered oxygen being made two and a half miles down, at the bottom of the Pacific Ocean. Their claim centred on small polymetallic nodules on the seafloor, and the key question - could these lumps of metal somehow be making oxygen in complete darkness? It was an extraordinary finding that, if proven, could overturn hundreds of years of scientific knowledge about how this crucial ingredient for life is made. It prompted global headlines and split scientists. But a year and a half on, are we any closer to knowing the answer... Is dark oxygen really possible? BBC News science correspondent Victoria Gill investigates for BBC Radio 4, and finds so much more than a scientific anomaly. Dark Breath is the story of a scientific controversy played out in real time. A row about science that became personal. And a discovery that crashed headlong into the debate about whether we should mine metals from the deep sea. What does the story tell us about the messy and human scientific process? And what bearing does it have on the decision to exploit some of the last untouched parts of our planet? Presenter: Victoria Gill Producer: Gerry Holt Editor: Ilan Goodman

The rapid spread of antibiotic resistant bacteria is already claiming lives - and a far greater global crisis is on the horizon. In this three part series for Discovery, reporter Roland Pease traces how we reached this point, uncovers the forces driving resistance ever faster, and meets the scientists racing to outpace evolving superbugs before our lifesaving medicines fail for good. Episode 3 - Failed market. A successful new antibiotic must not only treat bacteria that resist existing therapies, it must be kept in reserve for only the hardest cases lest new kinds of resistance evolve, and yet it must pay back the developers' investment. No wonder several leading antibiotic companies have failed financially in the past 8 years. Is there a way to make antibiotic development pay?

The rapid spread of antibiotic resistant bacteria is already claiming lives and a far greater global crisis is on the horizon. In this three part series for Discovery, reporter Roland Pease traces how we reached this point, uncovers the forces driving resistance ever faster, and meets the scientists racing to outpace evolving superbugs before our lifesaving medicines fail for good. Episode 2 - The chemists' challenge. With all the low-hanging fruit in the antibiotic search space gone, chemists are having to work harder and be cleverer to top up the antibiotic pipeline. The chances of finding even one successful compound in a working life are low, but can new approaches like AI or genetics make the difference?

The rapid spread of antibiotic resistant bacteria is already claiming lives and a far greater global crisis is on the horizon. In the first episode of a three-part series, reporter Roland Pease traces the rise of resistance since the discovery of penicillin, its consequences for patients, and how bacteria are getting widening the treatment gap.

Ever heard of the unsuccessful Dutch painter who decided to humiliate his critics by forging Vermeers, which the artworld subsequently dubbed 'masterpieces'? Or the businessman who bought a Marc Chagall painting that he displayed with pride for years, before a television investigation revealed to his horror that it was a fake? Today we're exploring the scientific techniques used to reveal forged artworks - and bring down scammers still trying to make millions from fake masterpieces. Jehane Ragai is an Emeritus Professor of Chemistry at the American University in Cairo, with a passion for science matched by her love of arts and culture. Early in her career Jehane helped analyse the Great Sphinx of Giza and later became fascinated by the world of art forgery, leading to her acclaimed book, ‘The Scientist and the Forger’. Her life has not been without its difficulties, but - perhaps unsurprisingly, as the daughter of renowned Egyptian feminist Doria Shafik - she’s not one to shy away from a challenge. And as she tells Professor Jim Al-Khalili, Jehane feels priveleged to have been able to integrate her twin passions into a career; advice she now passes on to her students

Tony Juniper is an environmentalist who has worn many hats, over the course of his career. After developing a passion for birds in childhood, his first job saw him working to save endangered parrots - including a successful effort to bring back the Spix's macaw from the edge of extinction. Tony went on to hold leading campaigning roles with some of the world's best known environmental organisations, from Friends of The Earth to the World Wildlife Fund. He also acted as an advisor to King Charles's International Sustainability Unit and co-authored three books with the monarch. Today, Tony has swapped lobbying and campaigning for advising the government, as head of the advisory body Natural England: not without its challenges, but he says they are still outweighed by the positives. Talking to Professor Jim Al-Khalili about his enduring love for nature and hopes for the future, Tony explains his optimism that we can and will recognise the urgent need to protect and restore our planet; and why ultimately, that means saving ourselves.

The COP30 climate summit is taking place in the Brazilian city of Belém, a gateway to the Amazon rainforest, which continues to face widespread deforestation. We all know that our climate is changing and that we are largely responsible for this, but we can’t tackle the problem unless we understand what’s going on. One scientist who’s done more than most to rectify this is Professor Pierre Friedlingstein. He’s a prominent climate scientist and Chair in Mathematical Modelling of the Climate System at Exeter University. His models have transformed our understanding of climate change, revealing a complex dynamical system with carbon at its centre, cycling between the atmosphere, oceans and land, to directly influence the level of carbon dioxide in the atmosphere. Pierre is actively involved in assessing the state of our climate through the Intergovernmental Panel on Climate Change and, as director of the Global Carbon Budget, estimates the remaining amount of carbon dioxide that can be emitted before we breach our global climate targets. It’s the ultimate test of effective climate action and the latest annual update will be released at COP. Pierre explains how we can all play our part to reduce carbon emissions, and he practises what he preaches - he won’t be flying to COP this year so as to minimise his own carbon footprint.

Imagine if you were listening to an opera or a Taylor Swift concert, and as the lights in the auditorium dimmed, the music was accompanied by a rainbow of colours only you could see. Perhaps while listening to your friends talking, you simultaneously experience a smorgasbord of tastes, with different words evoking different flavours, maybe a delicious ice cream, or something as disgusting as ear wax... This merging of the senses is known as synaesthesia, and it’s the rich research world of neuropsychologist Professor Julia Simner. Julia runs the Multisense lab at the University of Sussex and has pioneered research into understanding how special brains process our sensory world in special ways. In the studio she tests Jim to see if he might be a synaesthete or have aphantasia, which is the inability to view images in the mind’s eye. The results are surprising. Julia’s discovered links to autism, and to different personality types, as well as a number of previously unknown sensory differences. She describes her career and her life as a series of swerves, or sliding door moments, that have led her to study the subject and the people she’s passionate about. She says that the more she looks for these unusual traits in us the more she finds.

Caroline Smith is passionate about space rocks, whether they’re samples collected from the surface of asteroids and the Moon and hopefully Mars one day soon, or meteorites, those alien rock fragments that have survived their fiery descents through our atmosphere to land here on Earth. She is Head of Collections and Principal Curator of Meteorites at the Natural History Museum, home to one of the finest meteorite collections in the world. Her interest in rocks began while wandering the foothills of the Rocky Mountains, as a child, picking up the ones that caught her eye and bashing them with a hammer, hoping to find treasure inside, whether it’s gold, diamonds or dinosaur fossils. Her work today, studying rocks that have landed here on Earth or those still out there in space, is no less ambitious. She analyses their chemical composition looking for tantalising clues that might reveal how our Solar System formed, and potentially the presence of the chemical building blocks necessary for life itself.

From humble beginnings in his native Sri Lanka, to a more than 40 year academic career at Queen’s University Belfast, Prof. AP (Amilra Prasanna) De Silva’s research into molecular photosensors has led to a pioneering career in that’s evolved from chemistry to medical diagnostics on one hand, to information processing on the other. Prof. De Silva challenged cultural expectations and overcame the lack of opportunities in chemistry that were available in Sri Lanka in the early 1970s. He first moved to Belfast to pursue research in photochemistry at Queen’s University. Inspired by his grandmother’s struggle with high blood pressure he engineered a unique sodium photosensor by marrying fluorescent molecules with chemical receptors. As a result of his international collaborations, a commercial, portable sensor was developed to detect salts and minerals in the blood. Its speed of analysis has since saved countless lives and improved healthcare around the world. AP talks to Jim Al-Khalili about his passion for engineering molecules and how his photochemical innovations have since crossed into computer science. They’ve been developed to perform molecular computations far inside the human body - where silicon microchips fear to tread. A new deeper understanding of life inside our tissues and cells beckons.

In July 1545, King Henry VIII watched from Southsea Castle on England's south coast as his fleet sailed out to face the French - only to witness his prized warship, the Mary Rose, sink before his eyes. Raised from the Solent in 1982, the ship is now the centrepiece of the Mary Rose Museum, along with thousands more artefacts that were recovered from the seabed. But keeping the 500-year-old ship and its associated Tudor relics in good condition is no small task, which is where Dr Eleanor Schofield comes in. As Director of Collections at the Mary Rose Trust and a materials engineer by training, Eleanor has spent years tackling the unique scientific challenges of conserving centuries-old wood and metal. From the United States to Portsmouth, Eleanor's research is helping ensure this iconic vessel remains 'ship-shape' for generations to come. In a special edition of The Life Scientific, recorded in front of an audience at the museum in Portsmouth's Historic Dockyards, Professor Jim Al-Khalili discovers how cutting-edge science is keeping history afloat.

There are problems and tasks so hard and complicated that it would take today’s most powerful supercomputers millions of years to crack them. But in the next decade, we may well have quantum computers which could solve such problems in seconds. Professor Sir Peter Knight is a British pioneer in the realms of quantum optics and quantum information science. During his three decades as a researcher at Imperial College London, he has advanced our understanding of the physics which underpins how quantum computers work. Quantum optics was a new field of physics at the start of Peter Knight’s career in the early 1970s and he tells Jim Al-Khalili about the excitement and opportunities for a young scientist at the birth of a new scientific discipline. He also talks about the UK National Quantum Technologies Programme. Since his retirement in 2010, Peter Knight has been the driving force behind this £1 billion government-funded endeavour which has positioned the UK as a world leader in the development and commercialisation of quantum computing and other revolutionary quantum inventions.

The very latest developments in the world of Earth science with Roland Pease, recorded at the American Geophysical Union (AGU) meeting in New Orleans, where thousands of Earth, atmospheric, glacial, ocean and hydrologic scientists come together to promote discovery in Earth science for the benefit of humanity. Twenty years on, we discuss the enduring lessons from the Hurricane Katrina disaster of 2005, hearing from Lieutenant General Russel Honoré who led the military relief effort, and Roland speaks to Jill Trepanier, hurricane climatologist from Louisiana State University. We also hear about the mouth of the Mississippi River, known as the Bird's Foot Delta, south of New Orleans. Carol Wilson, assistant professor in the Department of Geology and Geophysics at Louisiana State University, tells us how important these wetlands are as storm protections, yet they’re under threat from sea level rise and lack of sediment. Roland takes a look at fifty-thousand-year-old Antarctic ice whilst speaking to Ed Brook, Professor at Oregon State University and director of COLDEX (Center for Oldest Ice Exploration), whose team is searching for ice which is potentially ten million years old. And he speaks to Allison Chartrand, assistant research scientist at the University of Maryland and NASA Goddard Space Flight Center, who has been working to reveal the hidden landscapes of Greenland under the ice. And Bob Hazen, scientist at the Carnegie Science Earth & Planets Laboratory, takes us back to the origins of life on Earth. He is investigating rocks which could be over four billion years old and may contain molecular fragments of ancient life. Presenter: Roland Pease Producer: Jonathan Blackwell

The very latest developments in the world of space science with Roland Pease, recorded at the American Geophysical Union (AGU) meeting in New Orleans, where thousands of space and planetary scientists come together to promote discovery in space science for the benefit of humanity. Roland talks to Andy Rivkin, planetary astronomer at the Johns Hopkins University Applied Physics Laboratory, about planetary defence from asteroids, including the small potential for asteroid 2024 YR4 to hit the moon in 2032. We hear from Craig DeForest, principle investigator for the PUNCH mission (Polarimeter to Unify the Corona and Heliosphere), which is a constellation of four small satellites that aim to learn how the Sun's corona becomes the solar wind. And Lara Waldrop, principle investigator of the Carruthers Geocorona Observatory, discusses the Earth's exosphere which plays an important role in Earth’s response to space weather caused by the Sun. We also talk lunar earthquakes, or moonquakes, and plans to put seismometers on the moon to measure them with Philippe Lognonné, professor at Université Paris Cité and planetary seismologist at Institut de Physique du Globe de Paris, and Ceri Nunn, lunar seismologist from NASA Jet Propulsion Laboratory. Presenter: Roland Pease Producer: Jonathan Blackwell

Quantum theory – our best understanding of the world at the smallest level – is famously weird and notoriously confusing. It’s a theory that seems to say particles can be in two places at once, or somehow “know” if you’re looking at them. Or at least, that’s what you might have heard. But is that really what quantum theory tells us about reality? To find out, presenter Marnie Chesterton travels to the birthplace of quantum theory: the remote, windswept island of Helgoland. Here, a century ago, a young scientist called Werner Heisenberg made a leap of understanding that laid the foundations of quantum mechanics, and changed the world. To mark a century of quantum, leading physicists from across the globe have gathered on Helgoland for a conference, and Marnie joins them with an unconventional plan. She’s allowed to ask them JUST ONE QUESTION, in the hope it can get to the heart of what this strange and difficult subject is really about: “What IS quantum?” Presenter: Marnie Chesterton Producer: Anand Jagatia Editor: Martin Smith Production Co-ordinator: Jazz George

"My ideas are often labelled as impossible, or useless, or both. Usually when people say that I'm on the right track." George Church is a geneticist, molecular engineer, and one of the pioneers of modern genomics. He's also someone who makes a habit of finding solutions to the seemingly impossible. Over the course of his career so far, George developed the first method for direct genomic sequencing, helped initiate the Human Genome Project, and founded the Personal Genome Project: making huge quantities of DNA data publicly available for research. Today, as a professor at Harvard Medical School and MIT, he’s working on some of the most headline-grabbing - and controversial - science on the planet: from the so-called "de-extinction" of woolly mammoths, to growing transplant-suitable organs in pigs, to virus-proofing humans. When inspiration strikes, there seems to be little that will slow him down - even the fact that he has narcolepsy, the neurological disorder that causes sudden sleep attacks. In fact, as George tells Professor Jim Al-Khalili, some of his best ideas come in those moments between waking and sleep...

Movies might have us believe that bomb disposal comes down to cutting the right wire. In fact, explosive devices are complex and varied - and learning how to dispose of them safely involves intense training, as well as the ability to stay calm under pressure. This was the world of Dr Gareth Collett, a retired British Army Brigadier General and engineer, specialising in bomb disposal; whose 32-year military career took him around the world, including heading up major ordnance clearance projects in Iraq and Afghanistan. After retiring from the army, Gareth became a university lecturer – but following his diagnosis with bladder cancer, started researching a possible link between bomb disposal veterans and higher rates of urological cancers. In conversation with Professor Jim Al-Khalili, Gareth discusses this ongoing research, dealing with PTSD - and why he just can't watch Oscar-winning movie The Hurt Locker...

Many people will be familiar with Parkinson’s disease: the progressive brain disorder that causes symptoms including tremors and slower movement, leading on to serious cognitive problems. You might not know that it’s the fastest-growing neurological condition in the world. Today it affects around 11.8 million people and that’s forecast to double by 2030. Dr Sonia Gandhi is one of the scientists working to change that trend. As Professor of Neurology at University College London and Assistant Research Director at the Francis Crick Institute, her work involves using stem cells to build models of the human brain, helping to drive the development of drugs and other therapies for Parkinson’s patients. Talking to Professor Jim Al-Khalili, Sonia explains why this destructive condition is on the rise - and the promising routes they're studying to find new ways to tackle it.

How do you feel about snakes? What about highly venomous ones? For Mark O’Shea, close encounters with the world’s most rare and deadly snakes are not only his profession, but his passion. Mark is a Professor of Herpetology - the area of zoology focusing on reptiles and amphibians - at the University of Wolverhampton. After dropping out of college in his teens, Mark's life could have taken a very different direction; but prompted by a fascination with reptiles that started with a childhood trip to the zoo, he's gone on to have a career spanning research, international expeditions and broadcasting. He's also worked with international medical teams, studying deadly species and helping to generate antidotes for some of the world’s deadliest venoms. In conversation with Professor Jim Al-Khalili, Mark reveals the challenges around generating antivenom for countries that need it, the pros and cons of keeping snakes as pets, and what you need to know if you ever get bitten... Presented by Jim Al-Khalili Produced by Lucy Taylor

What’s it like to wake up with a brand new voice? For those with foreign accent syndrome, this is their reality. Patients who develop this rare speech disorder start speaking in a brand new accent that they often have no connection to. So how does losing the voice you’ve known your entire life shape, or break, your identity? Presenter Ella Hubber speaks to Althia Bryden, who developed foreign accent syndrome last year, and Sarah Colwill, who has lived with the condition for the past 15 years. They share the deep impact it has had on their identity and connection to those around them. And to understand what is happening in the brain to cause this complete change in accent, and whether it’s really even an accent at all, Ella speaks to professor Nicholas Miller, who has been unpicking the mystery of foreign accent syndrome for decades. Also, professor Stefanie Keulen shares that there are actually multiple types of the condition. Even though foreign accent syndrome is rare, it is found around the world, can affect anyone, and highlights just how deeply our voices influence all aspects of our lives. Presenter: Ella Hubber Producers: Sophie Ormiston, Ella Hubber Assistant Producer: Minnie Harrop Editor: Martin Smith

We live in a time of automation and robotics; the machines run the factories, and AI will soon take all the jobs. Yet, even today, there are certain niche jobs where only an animal will do. Comedian and biologist Simon Watt meets some of them and the people who train them, study them, and love them. He starts with a business of ferrets (yes, that is their collective noun) at the National Ferret School in Derbyshire, who have swapped rabbit holes and trouser legs for drain-clearing, rewiring, and laying fibre optic cables. Ferret Trainer James McKay demonstrates why they are perfect for the job, as he casually folds one trainee into a tight pretzel. Simon visits the HQ of Medical Detection Dogs, a training facility in Milton Keynes where dogs are being trained to sniff the tell-tale signs of a host of diseases. You may have heard of their 'cancer dogs', but it goes much further - epilepsy, malaria, Parkinson's, even Covid-19. Dr Claire Guest explains. Although we have no real idea exactly how dogs do what they do, AI may be on the cusp of solving this puzzle for us. Simon speaks to Dr Andreas Mershin from start-up Realnose, which is developing “electronic noses". Finally, Simon meets some real heroes - HeroRats, to be precise. Not the same species that haunts our sewers, these are African Giant Pouched Rats, and their job as landmine detection specialists is saving lives across Thailand, Mozambique, Cambodia and Zimbabwe. Dr Cynthia Fast from UCLA trains them for the job. Presenter: Simon Watt Producer: Emily Knight

The London Anatomy Office accepts around 350 human bodies donated for medical research and education annually. You may imagine that these bodies are presevered in chemicals for medical students to study over weeks and months. And some are. But many are used - almost fresh - to train surgeons in the procedures which may one day save your life. Journalist Jenny Kleeman gains rare access to a surgical training course at Brighton and Sussex Medical School which uses these "fresh" donor bodies. She talks to the people who work with them every day and the surgeons who have come to be trained to find out how they feel about the people who have given the ultimate gift and if we still need real human cadavers in medical education. Presenter: Jenny Kleeman Producer: Ella Hubber

There can't be many people in the world who've saved lives in hospital emergency rooms and also helped care for the wellbeing of astronauts in space – but Kevin Fong’s career has followed a singular path: from astrophysics and trauma medicine, to working with NASA, to becoming an Air Ambulance doctor. Kevin is a consultant anaesthetist and professor of public engagement and innovation at University College London. He’s worked on the front line in hospitals, dealing with major incidents and helping shape policy; but he's also stayed true to his childhood passion for space, working on multiple projects with NASA and even going through the astronaut application process himself. As if that wasn’t enough, he’s also become a well-known figure in science broadcasting through his various radio and TV shows. Speaking to Professor Jim Al-Khalili, Kevin admits it hasn't always been an easy path – but his passion for both space and medicine have got him through. And today, he's channelling his energies into ensuring we protect the NHS's most precious commodity: its staff. Presented by Jim Al-Khalili Produced by Lucy Taylor Revised for World Service by Minnie Harrop

Chemical reactions are the backbone of modern society: the energy we use, the medicines we take, our housing materials, even the foods we eat, are created by reacting different substances together. If we zoom in, it’s the atoms within these substances that rearrange themselves to give rise to new substances with the properties we need. However, chemical reactions are far from perfect. They're often inefficient and their waste products can be harmful to the environment. Getting to grips with what goes on at the scale of individual atoms has long been a sticking point. Dame Pratibha Gai has spent much of her career pioneering novel microscopes to bring this seemingly inaccessible atomic world into sharp focus. Now Emeritus Professor of Chemistry at York University, her microscope, known as the environmental transmission electron microscope, is housed in labs around the world. It allows scientists, like herself, to observe chemical reactions in real-time, in exquisite atomic detail, and tinker with them to create products that are not only better for all of us, but also the environment. Presented by Jim Al-Khalili Produced by Beth Eastwood Revised for World Service by Minnie Harrop

Have you ever considered the lighter side of dark matter? Comedy has proved an unexpectedly succesful way to engage people with science - as today's guest knows first-hand. Astrophysicist Catherine Heymans is a Professor at the University of Edinburgh and the current Astronomer Royal for Scotland. She’s spent her career studying dark matter and dark energy: the mysterious ingredients that make up an estimated 95% of our cosmos, but which we still know surprisingly little about. Using increasingly powerful telescopes, both on earth and in space, Catherine has spent years building detailed maps of dark matter - even to the extent of capturing rare images of this mysterious cosmic component. On top of her research achievements, she's committed to making science accessible to all; not least by taking an astronomy-themed comedy show to the Edinburgh Festival and beyond. In conversation with Professor Jim Al-Khalili, Catherine talks about her passion for sharing the joys of astrophysics - and reveals how health challenges over the last few years have forced her to readdress her career, her ambitions and even her sense of self... Presented by Jim Al-Khalili Produced by Lucy Taylor Revised for World Service by Minnie Harrop

As a young man, traveling in Africa, Tim Coulson - now Professor of Zoology at the University of Oxford - became seriously ill with malaria and was told a second bout would probably kill him. Aged only 20, this brush with his own mortality led him to promise himself he would write a complete guide to science: life, the universe and everything. His aim was to understand the existence of all living things - no mean feat! Over the course of a colourful career, Tim's work has taken him all over the world: including researching wolves in Yellowstone National Park, little fish called guppies in the rivers of Trinidad and silvereye birds on Heron Island on the Great Barrier Reef. Using complicated mathematical models he builds up a picture of ecosystems seeking to explain how predators impact both evolution and ecosystems. And finally, more than thirty years after he vowed to write the book that would explain everything we know about science, he's done just that. In conversation with Professor Jim Al-Khalili, Tim talks about his journey from youthful ambition to science demystifier. Presented by Jim Al-Khalili Produced by Geraldine Fitzgerald Revised for World Service by Minnie Harrop

Have you ever pondered the fact that the universe is expanding? And not only that, it's expanding at an increasing speed - meaning everything around us is getting further and further away? If that isolating thought makes you feel slightly panicked, don't worry: this programme also contains wine! Brian Schmidt is a Distinguished Professor of Astrophysics at the Australian National University, known for his work on supernovae: massive explosions that take place when stars come to the ends of their lives. They are among the most energetic events in the universe and incredibly difficult to find; but that’s what his High-Z Supernova Search Team did, identifying enough of these rare and distant explosions to measure just how fast they were moving away from us. This led them to the realisation that, contrary to long-held belief in cosmology, the expansion of the universe was speeding up; a discovery which earned Brian a share of the 2011 Nobel Prize for Physics. As if that wasn't enough, he's gone on to discover one of the earliest stars in the universe; run a university; and become a winemaker, at his very own vineyard just outside Canberra. In a conversation spanning the genius phraseology of writer Douglas Adams, the importance of pisco sours, and the similarities between astronomy and viticulture, Brian tells Professor Jim Al-Khalili how his supernovae breakthrough paved the way for a revolution in astronomy - and where the field needs to go next... Presented by Jim Al-Khalili Produced for BBC Studios by Lucy Taylor Revised for World Service by Minnie Harrop

The celebrated primatologist Jane Goodall died last week at the age of 91. In tribute, we’re re-sharing this interview from 2020, where she reflects on the years she spent living with the wild chimpanzees in Gombe in eastern Tanzania and why she believes the best way to bring about change is to ‘creep into people’s hearts’. Jane shot to fame when she appeared on the cover of National Geographic magazine in 1963 and appeared in a documentary film directed by Orson Welles. Her ground breaking observations introduced us to the social and emotional lives of wild chimpanzees and changed our view of what it is to be human. Images of her younger self play-wrestling with baby chimps make Jane feel slightly apprehensive now but at the time she didn’t give it a second thought. However, she did take care to protect her young son. Seeing distressing footage of chimps who were living in captivity, she gave up fieldwork to become an activist, working to liberate chimpanzees that were being used for medical research or sold for meat or as pets, and setting up chimp sanctuaries for animals that were no longer able to live in the wild. For the last thirty years, she has campaigned gently but relentlessly to protect wild animals and wild places, touring the world and performing on stage in front of huge audiences. Her global youth programme, Roots and Shoots has inspired and empowered millions of people to understand and respect nature, leading some to call her ‘the mother Theresa of the environment’. A label she dislikes. Producer: Anna Buckley

How much information can you extract from a burnt fragment of human bone? Quite a lot, it turns out - not only about the individual, but also their broader lives and communities; and these are the stories unearthed by Jacqueline McKinley, a Principal Osteoarchaeologist with Wessex Archaeology. During her career, Jackie has analysed thousands of ancient burial sites across the British Isles, bringing to life the old traditions around death via often cremated human remains. She's also assisted criminal investigators with forensic analysis, and contributed to some of the UK's best-loved archaeological TV shows. And one thing she’s absolutely clear about: far from being macabre, osteoarchaeology is more about the living, than the dead... In conversation with Professor Jim Al-Khalili, Jackie talks about the stories we can derive from skeletal remains, how western attitudes to death have gone through a major recent shift, and why she's kept some of her late father's bones. Presented by Jim Al-Khalili Produced for BBC Studios by Lucy Taylor Reversion for World Service by Minnie Harrop

Surgeons often have to deal with the consequences of violent attacks - becoming all too familiar with patterns of public violence, and peaks around weekends, alcohol-infused events and occasions that bring together groups with conflicting ideals. Professor Jonathan Shepherd not only recognised the link between public violence and emergency hospital admissions, he actually did something about it. As a senior lecturer in Oral and Maxillofacial Surgery in the early 1980s, Jonathan started looking into this trend - and his research revealed that most violent assaults resulting in emergency hospital treatment are not reported to police. As a result, he devised the ‘Cardiff Model for Violence Prevention’: a programme where hospitals share data about admissions relating to violent attacks with local authorities. He also went on to study various aspects of violent assault and deliver evidence-based solutions - from alcohol restrictions in hotspots, to less breakable beer glasses in pubs. The impacts have been significant, delivering reductions in hospital admissions and in violent attacks recorded by police; not only in Cardiff, but in cities around the world where the model is used. Today, as an Emeritus Professor of Oral and Maxillofacial Surgery at Cardiff University - where he’s also Director of their Crime, Security and Intelligence Innovation Institute - Jonathan continues to bring together the medical sector with local authorities, finding practical ways to make cities and their residents safer. But his career, straddling the worlds of practise, science and policy, is an unusual one; here he talks to Professor Jim Al-Khalili about what drove him to make a difference. Presentedby Jim Al-Khalili Produced by Lucy Taylor Reversion for World Service by Minnie Harrop

Doyne Farmer is something of a rebel. Back in the seventies, when he was a student, he walked into a casino in Las Vegas, sat down at a roulette table and beat the house. To anyone watching the wheel spin and the ball clatter to its final resting place, his choice of number would’ve looked like a lucky guess. But knowing the physics of the game and armed with the world’s first wearable computer, which he’d designed, a seemingly random win was actually somewhat predictable. Doyne is an American scientist and entrepreneur who pioneered many of the fields that define the scientific agenda of our time, from chaos theory and complex systems to wearable computing. He uses big data and evermore powerful computers to apply complex systems science to the economy, to better predict our future. Much like roulette, economics can appear random but, with the right tools and understanding, it is anything but. Now Director of the Complexity Economics Programme at the Institute for New Economic Thinking at Oxford, Doyne says there’s a real need to act, to use these powers of prediction to help resolve one of the most pressing questions of our time - how best to prevent climate change. Presented by Jim Al-Khalili Produced by Beth Eastwood Reversion for World Service by Minnie Harrop

Elephants are the largest living land mammal and today our planet is home to three species: the African bush elephant, the African forest elephant, and the Asian elephant. But a hundred thousand years ago, in the chilly depths of the Ice Age, multiple species of elephant roamed the earth: from dog-sized dwarf elephants to towering woolly mammoths. These gentle giants' evolutionary story and its parallels with that of humankind has long fascinated Dr Tori Herridge, a senior lecturer in evolutionary biology at the University of Sheffield, where - as a seasoned science broadcaster - she's also responsible for their Masters course in Science Communication. Tori has spent much of her life studying fossil elephants and the sites where they were excavated; trying to establish facts behind relics that are far beyond the reach of Radio Carbon Dating. To date she's discovered dwarf mammoths on Mediterranean islands, retraced the groundbreaking Greek expedition of a female palaeontologist in the early 1900s, and even held an ancient woolly mammoth’s liver. (Verdict: stinky.) But as she tells Professor Jim Al-Khalili, this passion for fossil-hunting is not just about understanding the past: this information is what will help us protect present-day elephants and the world around them for future generations. Presented by Jim Al-Khalili Produced for BBC Studios by Lucy Taylor Reversion for World Service by Minnie Harrop

What does it take to earn the nickname, ‘The Leonardo da Vinci of heart surgery’? That's the moniker given to today's guest - a man who pioneered high-profile and often controversial procedures, but also helped drive huge medical progress; carrying out around 2,000 heart transplants and 400 dual heart-lung transplants during his 60-year career. Sir Magdi Yacoub is Emeritus Professor of Cardiothoracic Surgery at Imperial College London, and Director of Research at Harefield Hospital’s Magdi Yacoub Institute. Inspired by a surgeon father and impacted by the tragic early death of his aunt from a heart condition, his medical career includes various surgical firsts alongside numerous research projects, to further our understanding of and ability to treat heart disease. He headed up the teams that discovered it is possible to reverse heart failure, and that successfully grew part of a human heart valve from stem cells for the first time. But it hasn't always been plain sailing. At times, his work – such as early, unsuccessful transplant attempts, or using a baboon as a life-support system for a baby – attracted serious public criticism. Speaking to Professor Jim Al-Khalili, Sir Magdi reflects on the highs and lows of his cardio career, and offers his advice to the next generation of surgeons and researchers hoping to make their mark in heart medicine. Presented by Jim Al-Khalili Produced by Lucy Taylor Reversion for World Service by Minnie Harrop

Claudia de Rham has rather an unusual relationship with gravity. While she has spent her career exploring its fundamental nature, much of her free time has involved trying to defy it - from scuba diving in the Indian Ocean to piloting small aircraft over the Canadian waterfalls. Her ultimate ambition was to escape gravity’s clutches altogether and become an astronaut, a dream that was snatched away by an unlikely twist of fate. However, Claudia has no regrets - and says defying gravity for much of her life has helped her to truly understand it. As Professor of theoretical physics at Imperial College London, she now grapples with deep mathematics, where the fields of particle physics, gravity and cosmology intersect, on a quest to understand how the universe really works. She is a pioneer of the theory of massive gravity, a theory which could take us beyond even Einstein’s theory of relativity and shed light on why the universe is expanding at an ever-increasing rate. Presented by Jim Al-Khalili Produced for BBC Studios by Beth Eastwood Reversion for World Service by Minnie Harrop

When you think of Artificial Intelligence, does it inspire confidence, or concern? Although it's now generally accepted that this technology will play a major role in our future, a lot of conversations around AI and machine learning come back to the argument over us losing control and robots taking over. Happily, Neil Lawrence has a more optimistic view of the power of AI, and how we might navigate the potential pitfalls. Neil is the DeepMind Professor of Machine Learning at the University of Cambridge, and over the course of his career has been involved in deploying AI and machine learning in both academic and commercial scenarios, with a stint at Amazon as well as working across fields as varied as movie animation, Formula 1 strategy, and medical research. Speaking with Professor Jim Al-Khalili, Neil says ultimately his efforts are all about making a difference to our everyday lives - and that we need to learn how to embrace AI, albeit with a healthy dollop of scepticism; not least when it comes to how our data is used, and the power of 'the digital oligarchy'... Presented by Jim Al-Khalili Produced for BBC Studios by Lucy Taylor Reversion for World Service by Minnie Harrop

A frozen, white world at the far-reaches of the globe, where you're surrounded by snow and silence, might sound rather appealing. Factor in temperatures that drop to -57°C and a few of us might be put off - but for glaciologist Liz Morris, that's very much her happy place. Liz is an Emeritus Associate at the University of Cambridge’s Scott Polar Research Institute, and was among the first British women scientists to work on the planet’s coldest continent, Antarctica. Over the course of her career, Liz has gathered vital data on polar ice sheets and how they’re affected by climate change. She's also made numerous research trips across the Greenland Ice Shelf, and has a glacier named after her in Antarctica. In conversation with Professor Jim Al-Khalili, Liz discusses her fascination with glaciers and ice - and explains her unwavering determination to break into what was once a heavily male-dominated field. Presented by Jim Al-Khalili Produced for BBC Studios by Lucy Taylor Reversion for World Service by Minnie Harrop

Welcome to a world where medicine meets politics: a space that brings together scientific research, government wrangling, public push-back and healthcare conspiracies… Dr Anthony Fauci was the Director of America’s National Institute of Allergy and Infectious Diseases for nearly four decades, during which time he not only helped study, treat and prevent viruses such as HIV/AIDS and Covid-19; he also advised seven US Presidents, from Ronald Regan through to Joe Biden. Along the way, Tony Fauci's picked up a public profile and taken a fair amount of flack; not least because of his complicated relationship with President Donald Trump. But he's also made great strides in medical research and policy, from working with activists who initially challenged him on the government response to HIV/AIDS - to spearheading the USA's PEPFAR project to share vital medication with developing nations. In a candid conversation with Professor Jim Al-Khalili, Tony discusses his childhood in Brooklyn, the dark early days of the HIV/AIDS epidemic and lessons from the Covid-19. Presented by Jim Al-Khalili Produced for BBC Studios by Lucy Taylor Reversion for World Service by Minnie Harrop

Investigating an insect known for eating its prey alive – including, at times, its own species - the praying mantis! With bulging eyes and a triangular head, this predator uses it specially adapted front legs to trap its prey. Able to predate animals of a size much larger than themselves, including birds, lizards and even fish, presenter Adam Hart hears about their cultural significance to human populations all around the world, as well as addressing their reputation for sexual cannibalism. We also hear about their biomaterial qualities and potential importance in agriculture, and also look into a parasitic relationship the praying mantis has with a worm in South America which has given them the name ‘the mother of snakes’. Contributors: Dr. Julio Rivera, entomologist and researcher at the Université de Montréal in Canada and research associate at the Montréal Insectarium. Dr. Bianca Greyvenstein, postdoctoral fellow at North-West University in Potchefstroom and an expert in the praying mantises of South Africa. Presenter: Professor Adam Hart Producer: Jonathan Blackwell (Photo: Praying Mantis, Credit: Paul Starosta via Getty Images)

Investigating an elusive big cat known for its excellent tree climbing abilities - the leopard! This master of camouflage is found from the south of Africa to the far east of Asia – a spotted predator that stalks and ambushes its prey! Presenter Adam Hart will investigate their relationships with tigers and lions, as well as learning about a recent discovery that leopards each have their own unique roar. He’ll also discuss the future of the Arabian leopard and the potential for a reintroduction to Saudi Arabia, and find out about the role of synthetic fur capes known as ‘Heritage Furs’ in leopard conservation. Contributors: Dr. Gareth Mann, who is based in South Africa, is Leopard Program Director for Panthera, the global wild cat conservation organisation. Dr. Charlotte Searle, postdoctoral researcher and conservationist based in Tanzania, who is associated with the Wildlife Conservation Research Unit at the University of Oxford. Presenter: Professor Adam Hart Producer: Jonathan Blackwell Photo: Leopard in tree Credit: Valentin Wolf via Getty Images

On this episode of The Evidence, Claudia Hammond discusses all things hydration with a panel of experts. Where do our hydration guidelines come from? How do we determine the perfect amount of water we should drink? What are the issues with water access that people and populations face aroud the globe? And how will climate change affect the amount of water we need, and our access to it. In front of a live audience at the Wellcome Collection in London, Claudia discusses these questions and more with Neil Turner, nephrologist and professor emeritus at Edinburhg University, Yael Velleman, Director of Policy and Innovation at Unlimit Health, working at the intersection of water access, sanitation, and disease; and Anthony Acciavatti, an associate professor at Yale Architecture School and creator of the exhibtion Groundwater Earth: The World Before and After The Tubewell.

Named after a beast from Greek mythology, the harpy eagle is widely considered to be the most powerful bird of prey due to its strong legs and huge talons. With a crown of feathers atop its head, and known for eating monkeys and sloths, this regal-looking raptor dominates the rainforest canopies across much of South and Central America. Presenter Adam Hart looks into the folklore and cultural importance of these imposing birds, as well as finding out why these apex predators of the treetops are having to increasingly search for ground-dwelling prey such as armadillos. He also hears how harpy eagle researchers were the pioneers for biological applications of GPS in order to study and track these animals in the dense rainforest. Contributors: Dr. Helena Aguiar-Silva, biologist and associate research scientist at the National Institute for Amazonian Research and a member of Projeto Harpia Brasil. Dr. Eduardo Alvarez founder of a non-profit organisation called EarthMatters.org, to concentrate on the study and conservation of harpy eagles and to preserve their rainforest habitat. Presenter: Professor Adam Hart Producer: Jonathan Blackwell Image: Harpy eagle and nest with chick Credit: João Marcos Rosa

Investigating the black-and-white apex predator of the sea – the killer whale! Able to predate even great white sharks, this marine mammal is the largest member of the dolphin family. From tropical seas, to the Arctic and Antarctic, killer whales (or orcas) are found across the world. Living in family groups and often led by a post-menopausal matriarch, killer whales have passed on their hunting methods, which vary depending on which prey they specialise in hunting, through the generations. Presenter Adam Hart finds out about the killer whales incredible social behaviours (such as wearing salmon as hats) and hears how a dog is helping killer whale researchers access a gold mine of information about this predator. He also hears what challenges killer whale populations are facing and why killer whales may be attacking boats off the coast of the Iberian peninsula. Contributors: Dr. Leigh Hickmott, whale biologist and conservationist, who is an expert on Pack Ice killer whales, and whose research uses them as indicators to assess human disturbance of marine habitats. Dr. Deborah Giles, who is an expert on Southern Resident killer whales, based with the SeaDoc Society, a program of the Karen C. Drayer Wildlife Health Center at the UC Davis School of Veterinary Medicine. Presenter: Professor Adam Hart Producer: Jonathan Blackwell (Photo: Killer Whales, Credit: Serge MELESAN via Getty Images)

What's it like living underwater for two weeks? What's the trickiest part of training to be an astronaut? What are the most memorable sights you see from space? Several extreme questions, all of which can be answered by one man: Major Tim Peake. After a childhood packed with outdoor adventures, via the Cub Scouts and school Cadet Force, Tim joined the British Army Air Corps and became a military flying instructor then a test pilot; before eventually being selected as a European Space Agency (ESA) astronaut. In 2015, Tim became the first British ESA astronaut to visit the International Space Station. Over the course of a six-month mission, he took part in more than 250 scientific experiments and worked with more than two million schoolchildren across Europe. In a special New Year’s episode recorded in front of an audience at London’s Royal Society, Professor Jim Al-Khalili talks to Tim about his lifelong passion for adventure, the thrill of flight and why scientific experiments in space are so important. Presented by Jim Al-Khalili Produced by Lucy Taylor

What effect will warming temperatures have on health? One place to look for answers is Bulgaria. In the summer of 2023, Bulgaria experienced numerous heatwaves, leading to the country experiencing one of the highest rates of heat mortality in Europe. But how are these numbers calculated? How exactly does heat affect us? Who is most likely to suffer from ill health due to heat? And how can we protect ourselves in an increasingly warming world? Along with a panel of experts, Claudia Hammond will explore these questions and more with a live audience at the Sofia Science Festival in Bulgaria. Are we prepared for how rising temperatures will affect our health? This programme aims to find out.

From growing up in a progressive Denmark to studying mathematics at a gender-segregated Cambridge University, Inge Lehmann had to power through the shock of cultural change to pursue her love of mathematics. Whilst managing several seismological stations, Inge notices the peculiar readings in the data she was collecting. Was the Earth’s composition actually different to what the experts had thought? Dr Julia Ravey and Dr Ella Hubber tell the story of Danish seismologist Inge Lehmann who used earthquakes to uncover the truth about the composition of the Earth’s inner core. Presenters: Ella Hubber and Julia Ravey Guest Speakers: Dr Lif Lund Jacobsen and Dr Trine Dahl-Jensen Producers: Ella Hubber and Julia Ravey Assistant producers: Sophie Ormiston, Anna Charalambou and Josie Hardy Sound designer: Ella Roberts Production co-ordinator: Ishmael Soriano Editor: Holly Squire (Photo: Inge Lehmann Credit: Neuhaus, Even (6.2.1863-20.4.1946) /Royal Danish Library)

Dr Julia Ravey and Dr Ella Hubber are both scientists, but it turns out there’s a lot they don’t know about the women that came before them. In Unstoppable, Julia and Ella tell each other the hidden, world-shaping stories of the scientists, engineers and innovators that they wish they’d known about when they were starting out in science. This week, the story of a woman who gained her education by herding sheep during her childhood to becoming one of Africa’s most prominent scientists. Born under Apartheid in South Africa, Tebello Nyokong and her family uprooted their lives to escape the unequal education system enforced upon Black South Africans. After herding sheep proved she could do anything a boy could do, Tebello ended up studying science and found a love for chemistry. In the face of limited opportunities, she once again uprooted her life and took her studies oversees, but this was when she was introduced to something huge: a new, ground-breaking cancer treatment. Now Tebello is using nanotechnology to get this therapy off the ground, all while she fights to make Africa a science superpower. Presenters: Ella Hubber and Julia Ravey Guest Speaker: Professor Tebello Nyokong Producers: Ella Hubber and Julia Ravey Assistant producers: Sophie Ormiston, Anna Charalambou and Josie Hardy Sound Designer: Ella Roberts Production Coordinator: Ishmael Soriano Editor: Holly Squire (Image: Professor Tebello Nyokong. Credit: Professor Tebello Nyokong)

Dr Julia Ravey and Dr Ella Hubber are both scientists, but it turns out there’s a lot they don’t know about the women that came before them. In Unstoppable, Julia and Ella tell each other the hidden, world-shaping stories of the scientists, engineers and innovators that they wish they’d known about when they were starting out in science. This week, a Māori marine scientist is combining indigenous knowledge with marine science to save the oceans that are so integral to her heritage. Growing up in 1970s New Zealand, Kura-Paul Burke faced stigma due to her Māori roots. But, after finding herself studying marine science as an adult, Kura leaned on her heritage to take on a problem where many had already failed: restoring a lost population of precious, green-lipped mussels. Discover how Māori ancestresses, tribal elders and centuries-old knowledge inspired the ingenious methods of Aotearoa's first female Māori professor of marine science. Presenters: Ella Hubber and Julia Ravey Guest Speaker: Dr Kura Paul-Burke Producers: Ella Hubber and Julia Ravey Assistant Producers: Sophie Ormiston, Anna Charalambou and Josie Hardy Sound Designer: Ella Roberts Production Coordinator: Ishmael Soriano Editor: Holly Squire (Image: Dr Kura Paul-Burke. Credit: Dr Kura Paul-Burke)

Dr Julia Ravey and Dr Ella Hubber are both scientists, but it turns out there’s a lot they don’t know about the women that came before them. In Unstoppable, Julia and Ella tell each other the hidden, world-shaping stories of the scientists, engineers and innovators that they wish they’d known about when they were starting out in science. This week, the story of a young PhD student whose discovery of a previously unknown object in the universe won a Nobel Prize...but not for her. On a cold night in 1967, Jocelyn Bell Burnell sits alone in an observatory, reading the data from a radio telescope. As the pattern in the data suddenly changes, she realises she has discovered an entirely new kind of cosmic phenomenon. Uncover her life story, from getting snubbed for the Nobel Prize to paving our knowledge of distant and invisible aspects of the universe. Presenters: Ella Hubber and Julia Ravey Guest Speaker: Professor Dame Jocelyn Bell Burnell Producers: Ella Hubber and Julia Ravey Assistant Producers: Sophie Ormiston, Anna Charalambou and Josie Hardy Sound Designer: Ella Roberts Production Coordinator: Ishmael Soriano Editor: Holly Squire (Image: Jocelyn Bell Burnell attends the 2019 Breakthrough Prize at NASA Ames Research Center on November 4, 2018 in Mountain View, California. Credit: Kimberly White/Getty Images for Breakthrough Prize)

Dr Julia Ravey and Dr Ella Hubber are both scientists, but it turns out there’s a lot they don’t know about the women that came before them. In Unstoppable, Julia and Ella tell each other the hidden, world-shaping stories of the scientists, engineers and innovators that they wish they’d known about when they were starting out in science. This week, a Chinese malariologist who hunted for clues in ancient medical texts to find a cure for one of the world’s deadliest diseases. During a time of global political tension, the Chinese government set up a top-secret project to help communist troops in North Vietnam struggling with malaria. And tasked with this mission was young scientist, Tu Youyou. With a drive to help people after falling ill as a teenager and seeing the horrors of malaria firsthand, Tu turned to traditional Chinese medicine to look for potential treatments. And, after finding a hit, decided she should be the one to trial it... Named as arguably the most important pharmaceutical discovery in the last half-century, winning the 2015 Nobel Prize, discover how one woman used an overlooked herb combined with modern science to ultimately save millions of lives. Presenters: Ella Hubber and Julia Ravey Guest Speaker: Dr Xun Zhou Producers: Ella Hubber and Julia Ravey Assistant Producers: Sophie Ormiston, Anna Charalambou and Josie Hardy Sound Designer: Ella Roberts Production Coordinator: Ishmael Soriano Editor: Holly Squire (Image: Chief Professor Tu Youyou, laureate of the Nobel Prize in Physiology or Medicine acknowledges applause after she received her Nobel Prize from King Carl XVI Gustaf of Sweden during the Nobel Prize Awards Ceremony at Concert Hall on December 10, 2015 in Stockholm, Sweden. Credit: Pascal Le Segretain/WireImage via GettyImages)

Dr Julia Ravey and Dr Ella Hubber are both scientists, but it turns out there’s a lot they don’t know about the women that came before them. In Unstoppable, Julia and Ella tell each other the hidden, world-shaping stories of the scientists, engineers and innovators that they wish they’d known about when they were starting out in science. This week, the story of an Indian conservationist who combines stork preservation with female empowerment. On the banks of the Brahmaputra River in the Indian state of Assam, a young Purnima Barman discovers a love of storks whilst singing songs with her farmer grandmother. Fast forward decades later, she has created a community like no other by recruiting an army of over 20,000 village women to bring the Hargila storks from her childhood back from the brink of extinction. With their shared goal of restoring the relationship between the people and the wildlife, discover how Purnima is empowering women in the face of gender inequality. Presenters: Ella Hubber and Julia Ravey Guest Speaker: Dr Purnima Devi Barman Producers: Ella Hubber and Julia Ravey Assistant Producers: Sophie Ormiston, Anna Charalambou and Josie Hardy Sound Designer: Ella Roberts Production Coordinator: Ishmael Soriano Editor: Holly Squire (Image: Purnima Devi Barman. Credit: Purnima Devi Barman)

As the famous frog once said, it's not easy being green. And when it comes to decarbonising industry, indeed, reducing emissions of all sorts, the task is a complex one. Fossil fuels are used to manufacture some of mankind’s most ubiquitous products, from plastics to cement to steel; and even in areas where we’re trying to improve our footprint, there are repercussions. Mining lithium for electric car batteries isn’t exactly without impact. Add to the mix stories of corporations prioritising profits, and governments focusing on short-term popular policies – and it would be easy to feel disheartened. Professor Anna Korre says her role is to be the champion of science in this debate: providing clear evidence to help reduce environmental impacts, while allowing vital production processes to continue. Anna is an environmental engineer at Imperial College London and Co-Director of the university’s Energy Futures Lab. Her work has led to a risk model that's now used in mining operations around the world – and her current research into underground CO2 storage could hold the key to decarbonising British industry. But as she tells Jim Al-Khalili, social and family expectations when she was growing up in her native Greece meant her successful career in engineering very nearly didn't happen...

Rosalie David is a pioneer in the study of ancient Egypt. In the early 1970s, she launched a unique project to study Egyptian mummified bodies using the techniques of modern medicine. Back then, the vast majority of Egyptologists regarded mummies as unimportant sources of information about life in ancient Egypt. Instead they focussed on interpreting hieroglyphic inscriptions, the written record in papyrus documents and archaeological remains and artefacts. Rosalie David proved that the traditionalists were quite wrong. Professor David’s mummy research started at the Manchester Museum when she began to collaborate with radiologists at in Manchester, taking the museum’s mummies for x-rays at the hospital. Her multi-disciplinary team later moved to a dedicated institute at the University of Manchester, the KNH Centre for Biomedical Egyptology. Over the decades, the team there has made remarkable discoveries about disease and medicine in ancient Egyptian society, providing a new perspective on the history of medicine and giving extraordinary insights into the lives of individuals all those years ago. Rosalie tells Jim Al-Khalili about her journey from classics and ancient history to biomedicine, including some of her adventures in Egypt in the 1960s. She talks about some of her most significant research projects, and the 21st Century forensic detective work on the mummy of a young woman which revealed a gruesome murder 3,000 years ago...

In the summer of 2003, Europe experienced its most intense heatwave on record - one that saw more than 70,000 people lose their lives. Experiencing the effects whilst on holiday in Tuscany, climate scientist Peter Stott was struck by the idea that just maybe, he could use a modelling system developed by his team at the UK’s Meteorological Office, to study extreme weather events such as this very heatwave mathematically; and figure out the extent to which human influences were increasing their probability. That’s exactly what he went on to do - and, through this work and more, Peter has helped to shine a light on the causes and effects of climate change. His career, predominantly at the Meteorological Office, has seen him take on climate change sceptics and explain the intricacies of greenhouse gas emissions to global leaders. His work with the Intergovernmental Panel on Climate Change even earned him a share of the 2007 Nobel Peace Prize. But the biggest challenge remains: Peter talks to Jim Al-Khalili about whether humanity can adapt quickly enough to deal with the increasingly dangerous effects of our warming world...

Imagine a nanoparticle, less that a thousandth of the width of a human hair, that is so precise that it can carry a medicine to just where it’s needed in the body, improving the drug’s impact and reducing side effects. Ijeoma Uchegbu, Professor of Pharmaceutical Nanoscience at University College London, has spent her career with this goal in mind. She creates nanoparticles to carry medicines to regions of the body that are notoriously hard to reach, such as the back of the eye and the brain. With clinical trials in the pipeline, she hopes to treat blindness with eyedrops, transform pain relief and tackle the opioid crisis. Ijeoma took an unconventional route into science. Growing up in the UK and in Nigeria, she tells Professor Jim Al-Khalili her remarkable life story, from being fostered by a white family in rural Kent, while her Nigerian parents finished their studies, to struggling to pay the bills through her PhD as a single mum with young children. So passionate is Ijeoma to spread her love of science, she’s even turned to stand-up comedy to help get her message across!

Darren Croft studies one of the ocean’s most charismatic and spectacular animals – the killer whale. Orca are probably best known for their predatory behaviour: ganging up to catch hapless seals or attack other whales. But for the last fifteen years, Darren Croft’s focus has been on a gentler aspect of killer whale existence: their family and reproductive lives . Killer whales live in multi-generational family groups. Each family is led by an old matriarch, often well into her 80s. The rest of the group are her daughters and sons, and grand-children. Especially intriguing to Darren is that female orca go through something like the menopause - an extremely rare phenomenon in the animal kingdom, only documented in just five species of toothed whales and of course in humans. Halting female reproduction in midlife is an evolutionary mystery, but it is one which Darren Croft argues can be explained by studying killer whales. Darren is Professor of Animal Behaviour at the University of Exeter. He talks to Jim Al-Kalili about his research on killer whales, his previous work revealing sophisticated social behaviour in fish, his life on the farm, and the downsides and upsides of being dyslexic.

Bill Gates is one of the world's best-known billionaires - but after years at the corporate coalface building a software empire and a vast fortune, his priority now is giving that wealth away. And his ethos for doing it has been shaped by science. Famed for co-founding Microsoft, in recent decades Bill’s attention has turned to philanthropy via The Gates Foundation: one of the largest charities in the world. Since its inception in 2000, the organisation has helped tackle issues around health, education, inequality and climate change in some of the world’s poorest countries, with an undeniable impact, from contributing to the eradication of wild poliovirus in Africa, to helping halve global child mortality rates within 25 years. But, as Jim al-Khalili discovers, for a man with lofty ambitions and an even loftier bank balance Bill has surprisingly humble tastes.

A small, informal survey leads to shocking revelations about the US justice system, with its truths only uncovered decades later. Meanwhile, an ambitious portfolio manager discovers a perfect graph outlining eye-watering profits. But something does not seem right. Could the graph be accurate, or is it hiding a far more sinister truth? This story delves into the power of data, the hidden forces behind it, and the unexpected revelations that can change everything

At a conference in Mexico, one scientist’s outburst sparks a global quest to find a ‘golden spike’ - the boundary marking the shift into a new geological period dominated by humans, not volcanoes or asteroids. From plastics and concrete to nuclear fallout, the data they uncover reveals a planet profoundly altered. But can they convince their colleagues and the world of the extent of this transformation? Meanwhile, in a small Italian city nestled in the Apennine mountains, a series of low-level tremors raise the question: Is this just a passing phase, or a warning of something much more devastating?

A PhD student with a passion for whales stumbles upon a strange, eerie sound deep beneath the ocean waves, something that will soon rock her world. Meanwhile, a fisherman is stranded in the ocean late at night, completely alone. With time running out, can he be rescued before it is too late? From mysterious discoveries to life-or-death struggles, this story delves into the power of the ocean and the determination to survive.

Amid the desperation of war-starved Netherlands, a doctor defies conventional wisdom to save gravely ill children, uncovering a treatment that sparks both hope and controversy. Years later, in 1967, a young female researcher detects a strange, pulsing signal. Could it be mundane interference or evidence of alien life? From lifesaving breakthroughs to cosmic discoveries, this story celebrates the determination of pioneers who challenge convention and pursue truth against the odds.

A mathematician searching for love discovers that relationships aren’t always as simple as equations—are his calculations the issue, or is there something deeper at play? Meanwhile, at an engineering conference, a young researcher’s seemingly minor mistake uncovers a scandal of epic proportions. Can numbers find love or unveil problems? From personal dilemmas to professional revelations, this episode dives into the unexpected ways numbers can change lives.

In 2016, Niall McCann was left with a bruised spinal cord when he crashed his speed glider into the side of a mountain at 50mph. He shares his journey to recovery and some unexpected life lessons he has had to navigate, from soiling himself in inconvenient places and not being able to control his flatulence, to having to re-learn how to have sex again. We also hear from a Mountain Rescue medic on what looked like an “unsurvivable” situation and Niall’s surgeon on fixing his “exploded” spine.

Perhaps you couldn't drift off, or maybe you woke in the middle of the night and then couldn't nod off again. In this edition of Inside Health we're talking all about insomnia. It’s an issue that may affect many of us at some point in our lives – but for some it goes beyond a short period of not being able to sleep and becomes something more serious. James is joined by a trio of experts ready to answer to them: Dr Allie Hare, president of the British Sleep Society and consultant physician in sleep medicine at the Royal Brompton Hospital, Colin Espie, a professor of sleep medicine at Oxford University and Dr Faith Orchard, a lecturer in psychology at Sussex University. We’re going to find out why we get insomnia, when to seek help and how much factors like ageing, menopause, needing the loo or shift work matter. And we'll look at the latest advice and treatments. Can insomnia be fixed?

Dr Chris van Tulleken shares stories from the making of his chart-topping podcast, Fed. In conversation with Leyla Kazim, at Hay Festival 2024. In Fed, Dr Chris van Tulleken, investigated the entangled web of forces that shape what ends up on our plates. And he focused his investigation around one foodstuff in particular. The most widely eaten meat on our planet, a staple of nearly every diet and a global food production phenomenon: the humble chicken, Chris dug into the history of our relationship with this extraordinary animal, to try to get to the truth of why we eat so much of it, and what that means for the birds, for us, and for the planet. In this lively conversation, recorded live at Hay festival 2024, Chris talks to Leyla Kazim about the hidden stories behind the globalised food networks of today. From industrial-scale farming, to food labelling, to ethical dilemmas, environmental quandaries, and the complexities of the world of fast food. Plus tales from the adventure that ran through the whole series: raising his own tiny flock of broiler chickens, in his back garden.

From the Hay Festival, James and a panel of experts explain what we can all do to help ourselves age well. We discover what’s going on in our bodies when we age, the difference between biological and chronological age, as well as getting the audience moving for a physical test. James is joined by gerontologist Sarah Harper from the University of Oxford, biomedical scientist Georgina Ellison-Hughes from King’s College London, and doctor Norman Lazarus to understand how exercise, diet, and mental health all have a part to play in how we age.

Throbbing head, nausea, dizziness, disturbed vision – just some of the disabling symptoms that can strike during a migraine attack. This neurological condition is far more common than you might think, affecting more people than diabetes, epilepsy and asthma combined. While medications, to help relieve the symptoms of migraine, have been around for some time, they haven’t worked for everyone. And what happens in the brain during a migraine attack was, until recently, poorly understood. Peter Goadsby is Professor of Neurology at King's College London’s Institute of Psychiatry, Psychology & Neuroscience and is a true pioneer in the field of migraine. Over the course of his career, he has unravelled what happens in the brain during a migraine attack and his insights are already benefiting patients - in the form of new medications that can not only treat a migraine, but also prevent it from occurring. Peter shares this year’s Brain Prize, the world's largest prize for brain research, with three other internationally renowned scientists in the field.

Kip Thorne is an emeritus professor of theoretical physics at Caltech, the California Institute of Technology, and someone who has had a huge impact on our understanding of Einsteinian gravity. Over the course of his career Kip has broken new ground in the study of black holes, and been an integral parts of the team that recorded gravitational waves for the very first time – earning him a share in the 2017 Nobel Prize for Physics. He went on to promote physics in films: developing the original idea behind Christopher Nolan’s time-travel epic Interstellar and, since then, advising on scientific elements of various big-screen projects; including, most recently, the Oscar-winning Oppenheimer. In a special edition of The Life Scientific recorded in front of an audience of London’s Royal Institution, Prof Jim Al-Khalili talks to Kip about his life and career, from his Mormon upbringing in Utah to Hollywood collaborations – all through the lens of his unwavering passion for science.

It's summer - no really - and although the weather might have been mixed, the sporting line-up has been undeniably scorching - from the back-and-forth of Wimbledon, to the nail-biting Euros, to the current pageantry of the Summer Olympics. Next month the 2024 Paralympic Games get underway in Paris, involving the world’s very best para athletes; and Professor Vicky Tolfrey is at the forefront of the science that makes their sporting dreams a reality. Vicky is the Director of the Peter Harrison Centre for Disability Sport at Loughborough University, a hub for elite para-sport research. She’s worked with stars from the worlds of wheelchair athletics, basketball, rugby and tennis, amongst others – and in 2017, became the first European recipient of the International Paralympic Committee’s prestigious Scientific Award. She tells Professor Jim Al-Khalili about her work with elite para athletes, her experiences at major international sporting events, and her childhood dreams of becoming an Olympian herself.

The engineering industry, like many other STEM sectors, has a problem with diversity: one that Dawn Bonfield believes we can and must fix, if we're to get a handle on much more pressing planetary problems... Dawn is a materials engineer by background, who held roles at Citroën in France and British Aerospace in the UK. But, after having her third child, she made the difficult decision to leave the industry - as she thought at the time, for good. However a short spell working in post-natal services and childcare gave her new skills and a fresh perspective. This led to Dawn rehabilitating the struggling Women in Engineering Society and creating ‘International Women In Engineering Day’, which has just celebrated its 10th anniversary. Today, she’s Professor of Practice in Engineering for Sustainable Development at King’s College London, and the founder of Magnificent Women: a social enterprise celebrating the story of female engineers over the past century. She’s also President of the Commonwealth Engineers’ Council and has had her work supporting diversity and inclusion recognised with an MBE. Dawn talks to Professor Jim Al-Khalili about why 'inclusive engineering' should not be dismissed as tokenism, and why she's optimistic about the engineering sector's power to change the world.

In recent decades, we have taken huge steps forward in treating formerly fatal viruses - with pharmacological breakthroughs revolutionising treatment for conditions such as HIV, hepatitis and herpes. Raymond Schinazi has played a big role in that revolution. Ray was born in Egypt, where his mother’s brush with a potentially deadly illness during his childhood inspired a fascination with medicine. His childhood was scattered; after his family were forced to leave their homeland and travelled to Italy as refugees, Ray ended up on a scholarship to a British boarding school - and subsequently went on to study and flourish in the world of chemistry and biology. Today, Ray is the director of the Laboratory of Biochemical Pharmacology at Emory University in Atlanta, where he also set up the renowned Center for AIDS Research. His work in the early days of HIV studies led to drugs that many with the virus still take today; while his contribution to developing a cure for Hepatitis C has saved millions of lives around the world. Speaking to Jim al-Khalili, Ray reflects on his route to success and explains why he is confident that more big breakthroughs are on the horizon.

From anorexia nervosa to binge-eating, eating disorders are potentially fatal conditions that are traditionally very difficult to diagnose and treat - not least because those affected often don’t recognise that there’s anything wrong. But also because of the diverse factors that can influence and encourage them. Janet Treasure is a Professor of Psychiatry at King’s College, London - where she's focused on understanding the drivers behind these disorders, to help develop more effective treatments. Her study of twins in the 1980s offered one of the earliest arguments of a genetic link to anorexia, rather than the purely psychological motivations accepted at the time; while her most recent work explores holistic ways to better treat these conditions. Speaking to Jim Al-Khalili, Janet explains the work that's revealed anorexia's roots in both body and mind - as well as how attitudes towards eating disorders are slowly changing.

Marfan syndrome is a genetic disorder that makes renders the body’s connective tissues incredibly fragile; this can weaken the heart, leading to potentially fatal aneurysms. What’s more, anyone with the condition has a 50/50 chance of passing it on to their children. Dr Anne Child is a clinical geneticist who’s dedicated her professional life to finding answers and solutions for people affected by Marfan’s. Born in Canada, she met her British future-husband while working in Montreal in a case she describes as "love at first sight" - and in the 1970s she relocated her life to the UK. There, an encounter with a Marfan patient she was unable to help set Anne on a career path for life. She subsequently established the team that discovered the gene responsible for Marfan's, and founded the Marfan Trust to drive further research. Since then, life expectancy for those with the condition has jumped from 32 years old, to over 70. Speaking to Professor Jim Al-Khalili, Anne shares how she and her team achieved this remarkable turnaround.

Many of us have heard of seismology, the study of earthquakes; but what about asteroseismology, focusing on vibrations in stars? Conny Aerts is a professor of Astrophysics at the University of Leuven in Belgium - and a champion of this information-rich field of celestial research. Her work has broken new ground in helping to improve our understanding of stars and their structures. Conny describes herself as always being “something of an outlier” and she had to fight to follow her dream of working in astronomy. But that determination has paid off - today, Conny is involved in numerous interstellar studies collecting data from thousands of stars, and taking asteroseismology to a whole new level. Recorded at the 2024 Cheltenham Science Festival, Prof Jim Al-Khalili talks to the pioneering Belgian astrophysicist about her lifelong passion for stars, supporting the next generation of scientists, and her determination to tread her own path.

When does a crowd of people become unsafe? How well will the football team Aston Villa do next season? When is it cost-effective to replace a kitchen? The answers may seem arbitrary but, to Nira Chamberlain, they lie in mathematics. You can use maths to model virtually anything.

A top secret little-known mission that changed the outcome of World War II. Not Alan Turing's Enigma code-breaking mission but a daring foray, conducted behind enemy lines on the shores of Normandy. Harrison Lewis and wetland scientist Christian Dunn re-enact one of the most remarkable feats of the Second World War and discover the intricate details of the daring but forgotten science that underpinned D-Day.

Take a trip around the supermarket and you'll see shelves of products claiming to be 'high in protein'. Scroll through your social media and you'll find beautiful, sculpted people offering recipes and ideas for packing more protein into your diet. Science presenters Dr Julia Ravey and Dr Ella Hubber have noticed this too. They wanted to unpick the protein puzzle to find out what it does in our bodies and how much we really need. Can this macronutrient really help us lose weight, get fit and be healthier? Along the way, they speak to Professor Giles Yeo from the University of Cambridge, Bridget Benelam from the British Nutrition Foundation, Paralympian hopeful Harrison Walsh, and food historian Pen Vogler. Presenters: Dr Julia Ravey and Dr Ella Hubber Producer: Alice Lipscombe-Southwell Editor: Martin Smith

What is the universe made of? Where does space dust come from? And how exactly might one go about putting on a one-man-show about Sir Isaac Newton? These are all questions that Mike Edmunds, emeritus professor of astrophysics at Cardiff University and president of the Royal Astronomical Society (RAS), has tackled during his distinguished career. And although physics is his first love, Mike is fascinated by an array of scientific disciplines - with achievements ranging from interpreting the spread of chemical elements in the Universe, to decoding the world’s oldest-known astronomical artefact. Recording in front of an audience at the RAS in London, professor Jim al-Khalili talks to Mike about his life, work and inspirations. And who knows, Sir Isaac might even make an appearance.

With 86 billion nerve cells joined together in a network of 100 trillion connections, the human brain is the most complex system in the known universe. Dr Hannah Critchlow is an internationally acclaimed neuroscientist who has spent her career demystifying and explaining the brain to audiences around the world. Through her writing, broadcasting and lectures to audiences – whether in schools, festivals or online – she has become one of the public faces of neuroscience. She tells Prof Jim Al-Khalili that her desire to understand the brain began when she spent a year after school as a nursing assistant in a psychiatric hospital. The experience of working with young patients - many the same age as her - made her ask what it is within each individual brain which determines people’s very different life trajectories. In her books she explores the idea that much of our character and behaviour is hard-wired into us before we are even born. And most recently she has considered collective intelligence, asking how we can bring all our individual brains together and harness their power in one ‘super brain’. And we get to hear Jim’s own mind at work as Hannah attaches electrodes to his head and turns his brain waves into sound.

The reputation of the nuclear industry has had highs and lows during the career of Dr Fiona Rayment, the President of the Nuclear Institute. But nowadays the role of nuclear science and engineering has become more widely accepted in the quest for carbon net zero. Growing up in Hamilton, Scotland during a time of energy insecurity, Fiona was determined to understand more about why her school lacked the energy to heat up all of the classrooms or why there were power cuts causing her to have to do her homework by candlelight - and in nuclear she knew there was a possible solution. But it’s not just in clean energy that Fiona has spent her career, she’s also been involved in investigating how nuclear science can be used in treating cancer and space travel, as well as promoting gender diversity in the nuclear industry. Speaking to Professor Jim Al-Khalili, Fiona discusses how she’s always tried to keep close to the science during her career in order to keep her ‘spark’!

Dr Sheila Willis is a forensic scientist who was Director General of Forensic Science Ireland for many years. She has spent her life using science to help solve cases, working on crime scenes and then analysing material in the lab, and presenting scientific evidence in court. It’s a complicated business. Forensic science relies on powerful technology, such as DNA analysis, but it cannot be that alone - it’s also about human judgement, logical reasoning and asking the right questions. It is these fundamentals of forensic science that Sheila has fought for through her long career and what she fears may be becoming lost from the field now. We find out what happens when the two very different worlds of science and the law clash in the courtroom. How to walk the line of presenting scientific evidence where there is pressure to be definitive where often science cannot be - and what this part of the job has in common with food packaging. And what makes a good forensic scientist? We’ll turn the studio at London’s Broadcasting House into a live crime scene to see if host Professor Jim Al-Khalili would be any good as a forensic investigator…

Professor Charles Godfray, Director of the the Oxford Martin School tells Jim Al-Kahlili about the intricate world of population dynamics, and how a healthy obsession with parasitic wasps might help us solve some of humanity's biggest problems, from the fight against Malaria to sustainably feeding a global community of 9 billion people.

Sir Jonathan Van-Tam, or ‘JVT’ as he's arguably better known, first came to widespread public attention in his role as Deputy Chief Medical Officer during the Covid-19 pandemic. But even before that, Jonathan had built an impressive career based on a long-held fascination with respiratory illness and infectious diseases. He’s worked across the public and private sectors, contributing significantly to improving our understanding of influenza and treatments to address such viruses. It’s hard to believe that back in his teens, JVT – the man who advised the nation on pandemic precautions and helped make the UK’s vaccine roll-out possible – nearly didn’t get the grades he needed to go to medical school. But early challenges aside, Jonathan went on to discover a love for both medical research and public speaking: making complex public health messages easier to digest – not least by using analogies relating to his beloved football. Speaking to Professor Jim Al-Khalili in the first episode of a new series of The Life Scientific, Jonathan discusses his life and career: from academic emphasis in childhood and imposter syndrome at medical school, to pandemic pressures around Covid-19 and big birthday celebrations.

Dr Chris van Tulleken wrestles with the dilemma of slaughter. Could he bring himself to dispatch an animal himself? Is he happy supporting an industry which kills animals in his name? And if not, what could he eat instead? Chris explores the rise of the alternative protein industry – plant-based meat alternatives, lab-grown meat, or most shocking of all for some, actual meat abstinence, Veganism. And it is time to revisit that initial question: what’s influencing our choices when it comes to eating chicken, what impact is that having – and are we bothered?

We're a planet addicted to chicken and our appetites fuel a massive global industry, but is it one we should support? While some cite it as a shining example of a super-efficient food production system, one that could help drive food security around the world, others say it is a cruel, destructive and outdated structure that makes a few people richer while exploiting others – along with animals and the environment. In Brazil, one of the world’s biggest chicken and soya producers, our reporter Leonardo Milano hears accusations of threats and pollution relating to the feed sector; while in Africa, Dr Chris van Tulleken learns about poultry-farming initiatives helping to make struggling nations more food-secure. There are also other challenges that the industry is wrestling with: from antimicrobial resistance to the threat of another major global pandemic - bird flu. So is there a ‘big business bad guy’ to blame – or does responsibility lie closer to home, with unquestioning consumers like Chris?

Like many of us, Dr Chris van Tulleken is always trying to eat better food: healthy, high welfare, good for the environment. This kind of consumer demand is making the chicken industry better, in tiny increments. So why do so many of us give ourselves a pass when it comes to the food we know we should not be eating - fast food? Chicken is at the very heart of this industry. As a cheap meat that does not have a strong taste, can easily take on other flavours and does not have any religious restrictions, it’s the ideal takeaway ingredient; from nuggets to chow mein to tikka masala. And although we might be careful about chicken choices when buying it raw, somehow we don’t seem to mind turning a blind eye to the origins and nutritional content of our fast food favourites, especially if we’re hungry. Chris discovers just how bad this food can be for both us and the planet, and why we are powerless to resist it.

For eons, salt has been crucial to human health, culture, and diet. On this episode of The Evidence, we explore the strange science of salt taste – why it can be sweet, salty, or even a flavour enhancer. We look at how salt keeps our bodies running, and what happens if we have to little of it. And while too little salt may be bad, too much is also a problem. What does the science say about how much salt is optimal, and what can we do to make sure we’re eating the right amount? Claudia Hammond is joined by a panel of salty experts who will help find the answers to these questions and more.

Do YOU know what you're eating? Are you sure? Dr Chris van Tulleken is keen to make good food choices, and buy the best chicken possible for his dinner. High welfare, tasty, and good for the environment, ideally. But it's not as easy as that. How CAN he make good food choices if he has no idea what he's buying? Chris explores what we actually know about the food we buy, and to what extent we can trust what's on a label. He also uncovers the startling truth about two very different ways that we buy chicken - lifting the lid on why sometimes, even the most moral meat shoppers turn a blind eye...

We’ve heard about the potential problems around chicken welfare. But how does that square with their impact on the environment? Dr Chris van Tulleken finds out what it takes to produce the most eco-friendly chicken meat possible. And makes a devastating discovery. Welfare concerns, and environmental credentials, often pull in OPPOSITE directions. Does he want to eat the happiest birds, or the ones kindest to the planet? Halfway through his poultry quest, Chris remains massively conflicted: he loves chicken, but some of what he’s discovered makes him question how much he eats it. Will he still be able to look at it the same way as he goes deeper down the rabbit hole? And more importantly, should he keep serving it up to the family?

We eat chicken. A LOT of it. We might love the taste, but what about how we're treating those birds? After witnessing first-hand the reality of indoor chicken farming - how most of the chicken we eat is raised - Dr Chris van Tulleken wants to know: are the birds happy enough, or is our method of rearing cheap chicken actually cruel? If so, what’s the ‘happier’ alternative – and do carnivores like Chris care enough to pay the price for that, or does a love of meat ultimately trump ethics? Chris battles with his conscience, and finds the answer hard to stomach.

So we started farming this bird called chicken, and it spread around the world. But what does it actually TAKE to feed us the amount of chicken we want to consume? 100 years ago this was a scrawny, egg-laying bird, only good for a stew once her eggs ran out – no one ate chicken meat. Fast forward to today and it’s the most consumed protein on the planet. How did we come to eat it in the first place, and what are the consequences of producing chicken meat on the vast, industrial scales we now consume it? Dr Chris van Tulleken uncovers the extraordinary accident of history that birthed a new industry, and changed the way we eat – and think about – meat forever.

Dr Chris van Tulleken is on a mission to find out what we’re eating, why, and who or what might be influencing our decisions. And he’s starting his quest to uncover food truths with the most eaten meat in the world, and one of the most numerous animals on our planet: chicken. He’s recently been forced to confront a serious gap in his food knowledge - what happens before it gets to our plates - and has decided this, the world’s most popular meat, is an ideal starting point. Chris’ initial investigations reveal the vast scale of modern chicken consumption; and how a once revered jungle fowl was manipulated to become a modern food success story, a fast-growing heavy-breasted beast to feed the masses. Now, he's torn: is this a triumph of human ingenuity – or the creation of a monster?

Dr Julia Ravey and Dr Ella Hubber both have a love of science, but it turns out there’s a lot they don’t know about some of the leading women at the front of the inventing game. In Unstoppable, Dr Julia and Dr Ella tell each other the hidden, world-shaping stories of the engineers, innovators and inventors they wish they’d known about when they were starting out as scientists. This week, the inventor whose incredible capacity to solve problems inspired today’s most popular period products. Mary Beatrice Davidson Kenner – known as Beatrice – grew up in a family of inventors, creating her first invention at just six years old. And she didn’t stop there – she continued to invent throughout her adult life, including a new and improved sanitary pad in a time when there was still a big taboo around periods. However, as an African American woman during a time of racial segregation, Beatrice faced injustice and discrimination when trying to get her inventions patented. But if anything, this spurred Beatrice on, and at one point in time she held the most patents of any African American woman. Dr Julia and Dr Ella are joined by Professor Sharra Vostral and Ashleigh Coren as they tell Beatrice’s remarkable story. Presenters: Dr Ella Hubber and Dr Julia Ravey Producers: Ella Hubber and Julia Ravey Assistant producer: Sophie Ormiston Production co-ordinator: Elisabeth Tuohy Editor: Holly Squire

In her last year of high school, Olga González-Sanabria went on a field trip to the University of Puerto Rico’s school of engineering – and immediately knew that was what she wanted to do. She followed her passion and after university was recruited by Nasa, where she carried out instrumental work, without which we would not have the International Space Station. As the very first Latina woman working in engineering at Nasa, Olga’s career has not always been an easy ride, but is filled with remarkable achievements. Dr Ella and Dr Julia tell her story, and Olga herself gives us a first-hand account of her life so far. Presenters: Dr Ella Hubber and Dr Julia Ravey Producers: Ella Hubber and Julia Ravey Assistant producer: Sophie Ormiston Production co-ordinator: Elisabeth Tuohy Editor: Holly Squire (Photo: Olga González-Sanabria. Credit: Nasa Glenn Research Center)

In a lab in 1950s Kolkata, Asima Chatterjee laboriously extracts chemicals from the Indian snakeroot plant. She knows she will have to send the products away – she does not have the money or resources to analyse them in India. But the tireless and uncompromising chemist perseveres, and her work paved the way for modern-day chemotherapy treatments. Asima grew up in a time when it was uncommon for women in India to have an education, but went on to become a hugely influential figure in her field whose work is still repurposed and cited today. Dr Ella and Dr Julia take us through her inspirational journey, joined by Prof Sivapriya Kirubakaran and Dr Sarah O’Connor. Producer/presenter: Dr Ella Hubber and Dr Julia Ravey Assistant producer: Sophie Ormiston Production co-ordinator: Elisabeth Tuohy Editor: Holly Squire

Florence Bell’s scientific career began in the 1930s whilst studying at Cambridge University. The University did not grant degrees to women at the time, but this did not dissuade Florence. She was so talented at an imaging technique called X-ray crystallography that she started a PhD in the field – and it was during this time that she would make a pivotal discovery about the molecule of life. Florence is an unsung hero of the DNA story. Her work laid the foundation for a vital field of research, yet her contribution was buried for years. Dr Julia Ravey and Dr Ella Hubber tell Florence’s tale, with input from Dr Kersten Hall, science historian and visiting fellow at the University of Leeds. Producer/presenter: Dr Ella Hubber and Dr Julia Ravey Assistant producer: Sophie Ormiston Production co-ordinator: Elisabeth Tuohy Editor: Holly Squire (Photo: Florence Bell. Credit: Courtesy of her son Chris Sawyer. No reuse)

Dr Julia Ravey and Dr Ella Hubber both have a love of science, but it turns out there’s a lot they don’t know about some of the leading women at the front of the inventing game. In Unstoppable, Dr Julia and Dr Ella tell each other the hidden, world-shaping stories of the engineers, innovators and inventors they wish they’d known about when they were starting out as scientists. This week, the story of an engineer who turned plastic into gold, all starting from her mother’s backyard. Every day, around 500 tonnes of plastic waste is generated in the Kenyan city of Nairobi. Hardly any of it is recycled – but engineer Nzambi Matee is on a mission to change that. Frustrated by the level of pollution, in 2017 Nzambi constructed a laboratory in her mother’s backyard. It was here that she used her self-taught engineering skills to convert plastic waste into bricks that are stronger and more eco-friendly than concrete. Since then, Nzambi’s backyard operation has grown into a company – Gjenge Makers – and the bricks are widely used across Nairobi. And at only 31, Nzambi is just getting started. As Dr Julia and Dr Ella trace Nzambi’s journey, we hear from Nzambi herself about what it took to get to this point, as well as her ambitions for the future. Presenters: Dr Ella Hubber and Dr Julia Ravey Producers: Ella Hubber and Julia Ravey Assistant producer: Sophie Ormiston Production Coordinator: Elisabeth Tuohy Editor: Holly Squire (Photo: Nzambi Matee, Kenyan entrepreneur and inventor, holds plastic polymer recycled to make bricks. Credit: SIMON MAINA/AFP via Getty Images)

Dr Julia Ravey and Dr Ella Hubber both have a love of science, but it turns out there’s a lot they don’t know about some of the leading women at the front of the inventing game. In Unstoppable, Dr Julia and Dr Ella tell each other the hidden, world-shaping stories of the engineers, innovators and inventors they wish they’d known about when they were starting out as scientists. This week, the story of the Hollywood starlet whose brilliant ideas would go on to revolutionise the way we live. Known as the ‘most beautiful woman in film’ during the 1940s, Hedy Lamarr was one of the most in demand Hollywood actresses of her time. But she wasn’t just a movie star. From a young age, she also had a knack for inventing – she liked to take her toys apart just to see how they worked. And she carried this passion into her adult life – creating an invention that laid the groundwork for technology many of us couldn’t live without: Wi-Fi, Bluetooth, and GPS. But it didn’t come without struggle. Dr Julia and Dr Ella take us through Hedy’s remarkable journey, and we get a first-hand look into Hedy’s life from her daughter Denise Loder-DeLuca. Presenters: Dr Ella Hubber and Dr Julia Ravey Producers: Ella Hubber and Julia Ravey Assistant producer: Sophie Ormiston Production Coordinator: Elisabeth Tuohy Editor: Holly Squire (Photo: Hedy Lamarr, Austrian-born American actress and inventor. Credit: Eric Carpenter/John Kobal Foundation/Hulton Archive/Getty Images)

The process of childbirth can be painful yet amazing, but at times and in some places, also very dangerous. Recorded in Malawi, East Africa, Claudia Hammond is joined by a panel of maternal health experts to figure out why it is that the equivalent of a large jumbo jet full of women die every day due to pregnancy or childbirth. Together, they examine how so many women can still be at risk during this period despite a greater access to healthcare. They also look into whether an eighty-year-old drug could be a game-changer when it comes to haemorrhage. Plus, they consider a study of 1.3 million women which asked what it is that women actually want from maternal healthcare. With Owen Chikwaza from the Malawi Ministry of Health, Linda Mipando of Kamuzu University and Elimase Kamanga-Gama, Director of the White Ribbon Alliance Malawi, Claudia looks at the many challenges and successes within the field, drawing from local experiences to offer global insights. Produced by: Margaret Sessa-Hawkins Editor: Holly Squire Production Coordinator: Siobhan Maguire Presenter: Claudia Hammond Studio Engineers: Andrew Saunderson and David Sproule (Photo: Pregnant woman being examined by a doctor. Credit: Holly Squire BBC)

Underwater cameraman Roger Munns set himself and his team an incredible challenge. In 2008, they visited Tonga to film the biggest courtship ritual of the animal kingdom, the humpback heat run, for the very first time underwater and up close. In the first few days, Roger had intimate encounters with the whales but most of the time, he was sat on the back of the boat, waiting to find a heat run. After two unsuccessful weeks, he started to wonder whether they would ever see one. But a few days later somebody spotted a heat run, and everything sprang into action. Roger got in position and dove down ten meters underwater on a single breath. From then on, his job was just to wait and hold his camera ready. In a moment that seemed to stretch out time, he waited, nervously, for a group of 40-ton bus-sized whales to speed past him… And Victor Vescovo describes his adventures into the deep, diving to the deepest parts of all five oceans. Victor's longest dive was solo to the lowest point on Earth - the Challenger Deep at the bottom of the Marianas trench in the western Pacific. On reaching the bottom, some 35,853 feet below the ocean surface, should something have gone wrong, there was no hope of rescue. Victor describes his feelings before making this historic descent and on the way down. Touching down on the sea bed, he was astounded by the abundance of marine life. Victor describes how he hopes that the mapping, observations and sample collections he has made on his dives will advance scientific understanding of the deep oceans, and where his eternal quest to explore might take him next. Produced by Florian Bohr and Diane Hope Credits: Humpback whale mother and calf sounds - Acoustic Communications CNRS team & CETAMADA Humpback whale calf sounds - Lars Bejder (MMRP Hawaii), Peter T. Madsen (Aarhus University) & Simone Videsen (Aarhus University)

Primatologist Catherine Hobaiter has spent more of her adult life in the rain forests of Uganda, with family bands of chimpanzees, than she has with her own human family members. For more than 20 years now she has spent 6 months every year at a remote field station, getting up before dawn every day to observe and collect behavioural data on family bands of chimps as they wake up and go about their daily lives. What is she trying to find out, that has gripped her for so long? It turns out that life in a chimpanzee troupe is every bit as gripping as a soap opera. But there are many more moments of beauty, revelation and the joy of discovery, as Catherine pursues her continuing, multi-decadal quest to understand what it means to be a chimpanzee. And when Sara Dykman set out to bicycle with the monarch butterfly migration, from the mountains of central Mexico, across the USA to Canada, she didn't think about the 10,201 miles that she would cover. Coping with headwinds, heavy rain storms, and everything from dirt roads to busy highways were not the challenge for Sara though. It was seeing how little of the Monarch's only food plant, milkweed, was left for them to feed on during their amazing, multigenerational, multinational migration. However, Sara found solace in the many conservationists and backyard butterfly gardeners she met along the way, and in the 9000 schoolchildren she gave talks to en route. The most emotional part of the journey for Sara was the last three miles - arriving successfully back at the monarch's overwintering site in Mexico. Produced by Diane Hope. Credits: Monarch butterfly recordings - Robert Mackay

Professor Ben Garrod and Dr Jess French get under the skin (and blubber) of the California sea lion, to crack the key to its success both on land and at sea. Its ability to dive hundreds of meters down, keep warm in icy waters, and run on land, can all be explained through its unique internal anatomy. They are joined by zookeeper and sea lion trainer Mae Betts, who adds insight into the intelligence of these sleek marine mammals. Co-Presenters: Ben Garrod and Jess French Producer: Ella Hubber Editor: Martin Smith Production co-ordinator: Jana Bennett-Holesworth

The tiny sap-sucking aphid, at just a few millimetres long, is the scourge of many gardeners and crop-growers worldwide, spreading astonishingly rapidly and inflicting huge damage as it seeks to outwit many host plants’ natural defences. With insights and guidance from aphid expert George Seddon-Roberts at the John Innes Centre, Norwich, some delicate dissecting tools, and a state of the art microscope, Prof Ben Garrod and Dr Jess French delve inside this herbivorous insect to unravel the anatomy and physiology that has secured its extraordinary reproductive success, whilst offering new clues as to how we could curtail its damaging impact in the future. Co-Presenters: Ben Garrod and Jess French Executive producer: Adrian Washbourne Producer: Ella Hubber Editor: Martin Smith Production co-ordinator: Jana Bennett-Holesworth

Ominously called the lamb vulture, there are many myths and misconceptions surrounding the bearded vulture. Flying the mountainous ranges across central Asia and eastern Africa, with a wingspan of almost three meters, the bearded vulture is am impressive Old World vulture. Prof Ben Garrod and Dr Jess French are looking past the beautifully coloured plumage, and delving deep inside to learn what this bird of prey really eats and what keeps its great wings aloft.

Wild Inside returns for a new series to take a look at some of our planet’s most exceptional and unusual creatures from an entirely new perspective: the inside. Whilst we can learn a lot from observing the outside, the secrets to the success of any animal – whether they swim, fly, or hop – lies in their complex internal anatomy. How do these wild animals survive and thrive in harsh and changing environments? To truly understand we need to delve inside. Professor Ben Garrod, evolutionary biologist from the University of East Anglia, and expert veterinary surgeon Dr Jess French, open up and investigate what makes each of these animals unique, in terms of their extraordinary anatomy, behaviour and their evolutionary history. Along the way, they reveal some unique adaptations which give each species a leg (or claw) up in surviving in the big, wild world. The series begins with an icon of the outback – known best for its hopping, boxing, and cosy pouch – the red kangaroo. Despite the immense heat and lack of water, these marsupials dominate Australia, with their evolutionary history driving them to success. From the powerful legs which allow them to hop up to 40km an hour, to an unexpected reproductive system that keeps their populations plentiful, Ben, Jess and marsupial expert Dr Jack Ashby reveal a mammalian anatomy which holds many surprises.

Hannah Fry explores two tales of data and discovery. A young researcher gains access to a secretive data set and discovers a system causing harm to the very people it is supposed to help. One day a student makes a discovery which, if true, could shake the intellectual foundations of a global movement, and undermine politicians around the world. Producer: Lauren Armstrong Carter

Millions of women around the world experience the menopause each year; it’s an important milestone, which marks the end of their reproductive years. But every individual's experience of it is personal and unique. In some cultures, there's a stigma about this life stage – it's viewed with trepidation and as something to be dreaded. In other cultures, it's considered to be a fresh start - a time of greater freedom when women no longer have to worry about their menstrual cycles. In this edition, recorded at Northern Ireland Science Festival in Belfast, Claudia Hammond and her expert panel take a global look at the science of the menopause and debunk some myths along the way. As Claudia and her guests navigate their way through the menopause maze, they look at the most recent academic research in this area. They also discuss the physical and psychological symptoms, the lifestyle changes women can make and the different treatments available, including Hormone Replacement Therapy. Claudia also speaks to the American biological anthropologist who has dedicated an impressive 35 years of her life to studying the average age of the menopause in different countries - and finds out how hot flushes vary in different cultures. She also speaks to a doctor who is working hard to make women’s health less of a taboo subject in the community where she works. And she hears from a Professor of Reproductive Science who is setting up the UK's first menopause school. Producer: Sarah Parfitt Co-ordinator: Siobhan Maguire Editor: Holly Squire Sound engineers: Andrew Saunderson and Bill Maul Mix engineer: Bob Nettles Image used with permission of the Northern Ireland Science Festival

Hannah Fry explores two more tales of data and discovery. Gossip and rumour are plaguing a tile manufacturing company. The chatter is pulling morale to new lows, and amid it all, a question hangs in the air: who is spreading it? Can the science of networks find out? And, what is the secret to ageing well? One man believes he may have found the beginnings of an answer, and it is hiding in a convent. Produced by: Ilan Goodman and Lauren Armstrong Carter

Hannah Fry explores two tales of data and discovery. Do orangutans - or humans - experience a midlife crisis? Hidden deep in the data, two economists have found a surprising pattern: happiness is U shaped. And, John Carter has a terrible choice to make. One path offers glory, the other to death. His decision hinges on one graph, but can it help him take the right road? Produced by: Ilan Goodman and Lauren Armstrong Carter

Hannah Fry explores two tales of data and discovery. Two couples are brought together by a tragedy and a tatty piece of paper, which reveals a serial murderer hiding in plain sight. And, across the world in Singapore, a metro system is misbehaving wildly. The rail engineers and company officials are flummoxed. Can data save the day? Produced by: Ilan Goodman and Lauren Armstrong Carter

Hannah Fry explores two tales of data and discovery. In a few specific years across the 20th Century, the proportion of boys born, mysteriously spiked. We follow one researcher’s obsessive quest to find out why. And next, a tale of science and skulduggery. Michael Mann was a respected climate scientist, unknown outside of a small academic circle, until he produced a graph that shocked the world and changed his life forever. Producer: Ilan Goodman

Humans have a long-held fascination with the idea of Artificial Intelligence (AI) as a dystopian threat - from Mary Shelley's Frankenstein, through to the Terminator movies. But somehow, we still often think of this technology as 'futuristic', whereas in fact, it's already woven into the fabric of our daily lives, from facial recognition software to translator apps. And if we get too caught up in the entertaining sci-fi narrative around AI and the potential threat from machines, there is a more pressing danger that we overlook real and present concerns - from deep fakes to electoral disinformation. Michael Wooldridge is determined to demystify AI and explain how it can improve our lives, in a whole host of different ways. A professor of Computer Science at the University of Oxford, and the director of Foundational AI Research at the Alan Turing Institute, Mike believes the most common fears around this technology are "misplaced". In a special 300th edition of The Life Scientific, recorded in front of an audience at London's Royal Institution (RI), Mike tells Jim al-Khalili how he will use this year's prestigious RI Christmas Lectures to lift the lid on modern AI technology and discuss how far it could go in future. Mike also reminiscences about the days when sending an email was a thrilling novelty, discusses why people love talking to him about the Terminator at parties, and is even challenged to think up a novel future use of AI by ChatGPT. Presenter: Jim al-Khalili Producer: Lucy Taylor Audio editor: Sophie Ormiston Production co-ordinator: Jonathan Harris

How do you solve a problem like CO2? As the curtain closes on the world’s most important climate summit, we talk to a scientist who was at COP 28 and is working to solve our carbon dioxide problem. Professor Mercedes Maroto-Valer thinks saving the planet is still Mission Possible - but key to success is turning excess of the climate-busting gas, carbon dioxide, into something useful. And as Director of the Research Centre for Carbon Solutions at Heriot-Watt University and the UK’s Decarbonisation Champion, she has lots of innovative ideas on how to do this. She also has a great climate-themed suggestion for what you should say when someone asks your age… Presenter: Jim Al-Khalili Producer: Gerry Holt Audio editor: Sophie Ormiston Production Co-ordinator: Jonathan Harris

The Life Scientific zooms in to explore the intricate atomic make-up of metal alloys, with complex crystalline arrangements that can literally make or break structures integral to our everyday lives. Professor Sir Harry Bhadeshia is Professor of Metallurgy at Queen Mary University of London and Emeritus Tata Steel Professor of Metallurgy at the University of Cambridge. He’s been described as a ‘steel innovator’ – developing multiple new alloys with a host of real-world applications, from rail tracks to military armour. Harry’s prolific work in the field has earned him widespread recognition and a Knighthood; but it's not always been an easy ride... From his childhood in Kenya and an enforced move to the UK as a teenager, to the years standing up to those seeking to discredit the new path he was forging in steel research - Jim Al-Khalili discovers that Harry's achievements have required significant determination, as well as hard work. Presenter: Jim Al-Khalili Producer: Lucy Taylor Audio editor: Sophie Ormiston Production Co-ordinator: Jonathan Harris

“Big data” and “data science” are terms we hear more and more these days. The idea that we can use these vast amounts of information to understand and analyse phenomena, and find solutions to problems, is gaining prominence, both in business and academia. Cathie Sudlow, Professor of Neurology and Clinical Epidemiology at the University of Edinburgh, has been at the forefront of enabling health-related research using ever-increasing datasets. She tells presenter Jim Al-Khalili why this type of research matters and how the COVID-19 pandemic changed attitudes towards data in healthcare. Over the course of her career, Cathie has held a variety of roles at different organisations, and she is currently Chief Scientist and Deputy Director at Health Data Research UK. She believes that there is no room for prima donnas in science, and wants her field to be open and collaborative, to have the most impact on patients’ lives. Presenter: Jim Al-Khalili Producer: Florian Bohr Production Co-ordinator: Jonathan Harris

Professor Jim Al-Khalili meets one of Britain's greatest physicists, Sir Michael Berry. His work uncovers 'the arcane in the mundane', revealing the science that underpins phenomena in the world around us such as rainbows, and through his popular science lectures he joyfully explains the role of quantum mechanics in phones, computers and the technology that shapes the modern world. He is famed for the 'Berry phase' which is a key concept in quantum mechanics and one Sir Michael likes to explain through an analogy of holding a cat upside down and dropping it, or parallel parking a car. Presenter: Jim Al-Khalili Studio Producer: Tom Bonnett Audio Editor: Gerry Holt Production Co-ordinator: Jonathan Harris

People around the world are living longer and, on the whole, having fewer children. What does this mean for future populations? Sarah Harper CBE, Professor in Gerontology at the University of Oxford, tells presenter Jim Al-Khalili how it could affect pensions, why it might mean we work for longer, and discusses the ways modern life is changing global attitudes to when we have children, and whether we have them at all. Fertility and ageing have been Sarah's life's work and she tells her story of giving up a career in the media to carry out in-depth research, and going on to study population change in the UK and China, setting up the Oxford Institute of Population Ageing and later becoming a Scientific Advisor to UK Government. Presenter: Jim Al-Khalili Producer: Tom Bonnett Production Co-ordinator: Jonathan Harris

Our primate cousins fascinate us, with their uncanny similarities to us. Studying other apes and monkeys also helps us figure out the evolutionary puzzle of what makes us uniquely human. Sarah Blaffer Hrdy’s work brings a female perspective to this puzzle, correcting sexist stereotypes like the aggressive, philandering male and the coy, passive female. Sarah is professor emerita of anthropology at the University of California, Davis, and studies female primate behaviour to create a richer picture of our evolutionary history, as well as what it means to be a woman or a parent today. Her overarching aim is to understand the human condition, a goal she initially planned to pursue by writing novels. Instead, she found her way into science: her ground-breaking study of infanticide among langur monkeys in northern India overturned assumptions about these monkeys’ murderous motivations. Later in her career, she looked into reproductive and parenting strategies across species. We humans are primed by evolution, she believes, to need a lot of support raising our children. And that is a concern she found reflected in her own life, juggling family commitments with her career ambitions as a field researcher, teacher, and science writer.

The Life Scientific returns with a special episode from the USA; Princeton, New Jersey, to be precise. Here, the Institute for Advanced Study has hosted some of the greatest scientific minds of our time - Einstein was one of its first professors, J. Robert Oppenheimer its longest-serving director - and today's guest counts among them. Edward Witten is professor emeritus at the institute and the physicist behind M-Theory, a leading contender for what is commonly referred to as ‘the theory of everything’, uniting quantum mechanics and Einstein’s theory of gravity. He talks to Jim al-Khalili about a career that’s spanned some of the most exciting periods in modern theoretical physics - and about one particular problem that has obsessed and eluded him since his days as a student. Producer: Lucy Taylor

Exercise in older age is high on the agenda, but the idea that with age comes bags of time and a desire to ‘get out there’ isn’t true for a lot of us. How do you juggle exercise around caring for partners, grandchildren or staying in work? What if you haven’t exercised for years? What can your body take, and how has it changed with age? James Gallagher hears how octogenarian athlete ‘Irongran’ keeps going, he explores the mental and physical barriers that stop us exercising and he finds out what he might feel like in 40 years as he pulls on an ageing suit. (Photo: Elderly man going for a run. Credit: Charday Penn / Getty Images)

How many hours do you spend sitting down per day? Six? Maybe eight? Or 10? Between commuting, working and relaxing, sitting can soon add up to hours and hours. James Gallagher delves into the science to find out exactly how much sitting is too much; when does it become worrying for our health? James visits a lab to explore what prolonged sitting does to the body and he’ll find out whether there’s anything you can do to offset the effects of sitting a lot. We’ll hear about the origins of sitting research - and just because we like to explore every angle on a topic, we’ll hear all about why standing too much can also be a worry. (Photo: Woman sitting at desk in office. Credit: Richard Drury / Getty Images)

A look at the evidence that links the health of our mouths with the rest of our bodies.

Adam Hart investigates the fastest land animal in the world – the cheetah! Built for high-speed chases, these spotted cats are slender, with semi-retractable claws for good grip and a flexible spine plus a long tail for balance and manoeuvrability. Cheetahs rely on speed over brute strength when hunting – and can make tight, quick turns to shift course in fast pursuit of their prey. But with shrinking populations cheetahs are classified as vulnerable – so what’s being done in terms of conservation and are these projects having any success? Adam hears how cheetahs differ from lions and leopards and learns about their relationships with other predators. He looks at their unique adaptions and behaviours, as well as the different approaches that conservationists are undertaking to try and reverse the population decline. And we also hear about the re-introduction of cheetahs to India. Contributors: Professor Sarah Durant is from the Zoological Society of London and is project leader of the Africa Range-Wide Cheetah Conservation Initiative. Vincent van der Merwe is director of The Metapopulation Initiative and is cheetah metapopulation coordinator for Southern Africa and India. Presenter: Professor Adam Hart Producer: Jonathan Blackwell Editor: Holly Squire Production Coordinator: Jonathan Harris Studio Manager: Andrew Garratt (Photo: Cheetah, Credit: Paul & Paveena Mckenzie via Getty Images)

Adam Hart investigates a frenzied and voracious fish from South America – the piranha! Said to be able to strip their prey to the bone in mere minutes, there are plenty of gruesome tales about the bubbling bloodbaths that occur when shoals of these hardy fish feed in the freshwaters across South America - from up in Venezuela in the Orinoco River, to the Amazon and down to the Paraná River in Argentina. What role did former United States President Theodore Roosevelt have in creating the piranha’s fearsome reputation? And is this reputation misguided? Adam hears what piranhas are really like, both in the wild and in captivity. He learns about how these fish hunt, the impact that humans are having on them and tries to establish if they really are as bloodthirsty as we’ve been led to believe. Contributors: Marcelo Ândrade is a professor at the Federal University of Maranhão in Brazil. He researches the environments that piranha live in and their behaviour, as well as plastic ingestion by piranhas. Hannah Thomas is the aquarium team manager at Chester Zoo in the UK where they care for 40 red-bellied piranhas. Presenter: Professor Adam Hart Producer: Jonathan Blackwell Editor: Holly Squire Production Coordinator: Jonathan Harris Studio Manager: Neva Missirian (Photo: Red-Bellied Piranha, Credit: Ed Reschke via Getty Images)

Adam Hart investigates the most famous and feared predator in all the ocean – the great white shark! With rows of large, serrated teeth, it’s often thought of as a ferocious man-eater and was the villain of the film Jaws – which frightened a generation of beachgoers. This star of the silver screen may be the subject of fascination and fright for many, but is it really the ultimate predator of the ocean as Hollywood has led us to believe? Adam hears what it’s like to see these sharks up-close and in person for the very first time. He learns more about how great whites detect and hunt their prey, as well as the challenges they’ve been facing due to another ocean predator. Contributors: Dr Alison Towner is a postdoctoral researcher at Rhodes University in South Africa. She has a PhD in white shark ecology and has been studying the displacement of great whites due to orcas (killer whales) in South Africa. Professor Gavin Naylor is Director of the Florida Program for Shark Research. He is a biologist who has specialised in evolutionary and population genetics, focusing on sharks. Presenter: Professor Adam Hart Producer: Jonathan Blackwell Editor: Holly Squire Production Coordinator: Jonathan Harris Studio Manager: Jackie Margerum (Photo: Great White Shark, Credit: Todd Winner/Stocktrek Images via Getty Images)

Adam Hart investigates the largest terrestrial member of the weasel family – the wolverine. They’re far more than just a superhero played by Hugh Jackman! With a reputation for gluttony and ferocity, these solitary killers use snowstorms to hunt much larger prey. Found in the snowy tundra and boreal forests of the Northern Hemisphere, their future looks uncertain – they've come into conflict with Scandinavian farmers by hunting their reindeer and are threatened by climate change in North America and Mongolia. But have we misunderstood wolverines? And can we learn to co-exist with them? Contributors: Rebecca Watters is founder and director of the Mongolian Wolverine Project, as well as the executive director of the Wolverine Foundation, a non-profit that’s dedicated to advancing science-based conservation of wolverines. Jenny Mattisson is a researcher at the Norwegian Institute for Nature Research, who is involved in the monitoring of wolverines in Scandinavia. She has studied interactions between wolverines and Eurasian lynx, as well as their predation of reindeer. Presenter: Professor Adam Hart Producer: Jonathan Blackwell Editor: Holly Squire Production Coordinator: Jonathan Harris Studio Manager: Donald MacDonald (Photo: Wolverine, Credit: Arterra/Universal Images Group via Getty Images)

With the world's biodiversity being lost at an alarming rate, Alexandre Antonelli, Director of Science at the Royal Botanic Gardens, Kew, has made it his life's mission to protect it. He is a bio-geographer revealing how changes to the Earth's landscape, such as the formation of mountain ranges and rainforests, leads to the evolution of new species and causes plants, fungi and animals to move around the world. His work is a masterclass in joined-up thinking, bringing together different fields of research by starting conversations between scientists who would rarely talk to one another. Together, they paint a more holistic picture of how our planet's biodiversity has developed in the hope of informing how we can protect it in the future. Alex tells presenter Jim Al-Khalili about a life spent in the wild, beginning with his earliest memories of growing up in Brazil cataloguing life in the Atlantic Rainforest. That passion is still with him today. We've only scratched the surface of understanding what lives here on Earth, he says, more than 4,000 new species are found every year. Alex is passionate that we need to speed up the rate at which we document the richness of life, arguing if we don't identify what there is we can't protect it.

Astronomer Paul Murdin believes a good imagination is vital for scientists, since they're so often dealing with subjects outside the visible realm. Indeed, over a long and successful career his imagination has taken him on a journey through space, discovering various new and unusual celestial occurrences - notably the first successful identification of a black hole, Cygnus X-1. Paul tells Jim Al-Khalili how he spent much of his career at the Royal Greenwich Observatory, working with astronomers around the world on some of the most advanced telescopes ever built. He headed up the Astronomy section of the UK’s Particle Physics and Astronomy Research Council, was Director of Science for the British National Space Centre and even has an asteroid named after him. This list of achievements is testament to the fact that Paul has never let his disability hold him back; a leg brace and walking sticks have been part of his life since contracting polio in childhood. But he maintains that as long as you have curiosity and a vibrant imagination, nothing should stand in your way. (Photo: Paul Murdin in 1971 next to the Isaac Newton Telescope at the time of the discovery with that telescope of Cygnus X-1. Credit: Paul Murdin)

Some of the most complex medicines available today are made from living cells or organisms - these treatments are called bio-pharmaceuticals and in this episode of The Life Scientific Dr Bahija Jallal, CEO of Immunocore, shares her story of leaving her home in Casablanca, Morocco to become a world leader in developing bio-pharmaceutical cancer treatments. She tells Professor Jim Al-Khalili that she has always found herself ahead of the curve. When she began in oncology, the study of cancer, the common treatment was chemotherapy which attacked all the cells in an affected area. Her first studies into cancer treatments were looking at how certain therapies could focus in on the cancerous cells and move away from what she describes as the 'sledgehammer' of traditional chemotherapy. It was an early step in what became known as targeted cancer therapies, and it set Bahjia on course for a career dedicated to developing innovative drugs to improve cancer patients' lives. Through a deep understanding of the science and a resolute commitment to putting treatments in the hands of people who need them, she has produced astonishing results.

Reproductive science has come a long way in recent years, but there's still plenty we don't understand - particularly around male fertility. The reliability and availability of data in this field has become more of a concern in light of a study published this year, suggesting that sperm counts worldwide have dropped 62% in the past 50 years. As yet there is no clear answer as to why that is. Professor Chris Barratt is one of the scientists working to change that. He's the Head of Reproductive Medicine at Ninewells Hospital and the University of Dundee Medical School, and has dedicated his career to better understanding male infertility; driving breakthroughs in how to study sperm dysfunctions – and most recently spearheading advances in developing a male contraceptive pill. Chris talks to Professor Jim Al-Khalili about his academic struggles as a youngster, the lecture that changed his life, his research into 'head-banging sperm' and why he believes a new male contraceptive could be a game-changer.

We’re used to hearing the stories of scientists who study the world as it is now but what about the study of the past - what can this tell us about our future? Gideon Henderson’s research focuses on trying to understand climate change by looking at what was happening on our planet thousands of years ago. His work has taken him all around the world - to the deepest oceans and the darkest caves - where he collects samples containing radioactive isotopes which he uses as “clocks” to date past ice ages and other major climate events. As a geochemist and Professor of Earth Sciences at the University of Oxford, his work deals with the biggest questions, like our impact on the carbon cycle and climate, the health of our oceans, and finding new ways to remove greenhouse gases from the atmosphere. But in his role as Chief Scientific Adviser at the Department of Environment, Food and Rural Affairs, he also very much works on the present, at the intersection between the worlds of research and policy. He has overseen the decision to allow gene-edited food to be developed commercially in England and a UK surveillance programme to spot the Covid-19 virus in our waste-water. (Photo: Gideon Henderson. Credit: Gideon Henderson)

If you’ve ever seen the ocean during a storm, you’ll understand the extraordinary power contained in waves. On an island nation like Britain, that power could well be harnessed to produce clean energy; so why have we barely begun to tap this bountiful resource? Deborah Greaves is trying to change that. As Professor of Ocean Engineering at the University of Plymouth, she combines physical wave tanks with sophisticated computer modelling to test how well wave power devices respond to stormy seas. And as Director of the Supergen ORE Hub, she brings together researchers in offshore renewable energy to imagine a future of widespread, eco-friendly ocean power. Deborah tells Jim Al-Khalili about growing up in Plymouth fascinated by the sea, and about breaking from the norm in her arts-focused family, to pursue a degree in engineering. But she spent years as a civil engineer building tunnels for the London Underground - and going on expeditions to the Arctic with her husband - before undertaking a PhD at Oxford University, exploring what happens when waves crash into solid structures. She eventually returned to Plymouth and set up the institute’s Coastal, Ocean and Sediment Transport (COAST) Laboratory - a building with a swimming-pool-sized wave tank for testing new technologies. As Jim hears, these wave devices have an extraordinary diversity of uses - and could help to propel Britain into a greener energy future. (Photo: Deborah Greaves. Credit: Deborah Greaves)

Erica McAlister on the bee intellect and whether bigger brains are always better. Plus cockroaches may be reviled by many people, but Erica discovers the extraordinary flexibility of their simple nervous system led to the birth of neuroendocrinology. (Photo: A honey bee feeding on nectar from Echinacea purpurea. Credit: Barnaby Perkins)

What are allergies and what is the purpose of them? What can we do to try and prevent them? And what are the best ways of accurately and safely diagnosing them?

Erica McAlister on the innocuous wasp-like black soldier fly, a crown jewel of a fast-growing insect farming industry that's addressing the urgent need to find cheap clean protein. And how Namib Desert beetles have evolved in a very special environment, where the only source of water exists in the air. (Image: Desert beetle in Namib desert. Credit: Martin Harvey/Getty Images)

Blowflies may be some of the most reviled insects on the planet, but as Erica McAlister discovers, they are central to the surprisingly long tradition of forensic entomology and how there's more than meets the eye in the distinctive structural colour of the morpho butterfly wing, whose dazzling sheen is a key for camouflage and commerce. (Photo: A fly on a leaf. Credit: Christina Bollen/Getty Images)

Dr Erica McAlister uncovers a treasure trove of remarkable insights from the insect world including the innocuous flies that are Drosophila melanogaster. More is known about these flies than any other animal on the planet, as a model for human genetics. And the hoverfly that arguably undergoes the biggest transformation of any animal and how insect metamorphosis could be a tool to track future climate change. Producer: Adrian Washbourne Presenter: Dr Erica McAlister (Photo: Drosophila melanogaster. Credit: nechaev-kon/Getty Images)

Dr Erica McAlister uncovers a treasure trove of remarkable insects from the humble flea whose jump enables them to fly without wings and the mystery of the hawkmoth’s tongue, whose varying length has offered the simplest and most effective proof of Charles Darwin's theory of natural selection in action. Producer: Dr Adrian Washbourne Presenter: Dr Erica McAlister (Photo: Dr Erica McAlister. Credit: Dr Erica McAlister)

Imagine a world in which your laptop or mobile device accesses the internet, not via radio waves – or WiFi – as it does today but by using light instead: LiFi. Well, that world may not be as far away as you might think. In fact, the technology is already here; and it’s thanks in large part to the engineering ingenuity of Harald Haas, Distinguished Professor of Mobile Communications and Director of the Li-Fi Research and Development Centre at the University of Strathclyde. He tells Jim Al-Khalili about the two decades he has spent researching optical wireless communications, building up to his LiFi breakthrough in 2011, where he made waves in the scientific community and beyond by showing how a simple desk lamp could be used to stream a video. Harald’s research could well have a very real impact on people’s lives, reinventing the way we connect online – but, as Jim hears, his early life was dogged by a very real fear he may have the same devastating disease that took his mother's life at an early age; an experience that shaped his early years and which has driven him to succeed in his own life and career. (Image: Harald Haas. Credit: Harald Haas)

Anne-Marie Imafidon passed her computing A-Level at the age of 11 and by 16, was accepted to the University of Oxford to study Maths and Computer Science. She's used to the 'child prodigy' label that's followed her throughout her career, but that doesn't mean she's had an easy ride. It was a combination of personal experience and the discovery that the number of women working in the STEM sectors - Science, Technology, Engineering and Mathematics - was in free-fall that inspired Anne-Marie to found Stemettes: a not-for-profit social enterprise introducing girls to STEM ideas and careers in fun and accessible ways. It's now in its tenth year and still growing, while Anne-Marie has received an MBE, enjoyed a successful stint as the numbers guru on the TV series Countdown, and is the current President of the British Science Association. In conversation in front of an audience at the UK's 2023 Cheltenham Science Festival, she tells Jim Al-Khalili about her quest for equality and diversity across the scientific community - and explains why she thinks everyone has the potential to be a 'child prodigy', given the right opportunity... (Image: Anne-Marie Imafidon. Credit: Anne-Marie Imafidon)

Our genes can tell us so much about us, from why we look the way we look, think the way we think, even what kind of diseases we might be likely to suffer from. But our genes aren't the whole story. There are other, complex and intriguing systems within every cell in our bodies which control which of our tens-of-thousands of genes are switched on, or off, in different parts of the body, and under different circumstances. Welcome to the fascinating world of 'epigenetics', which our guest, the molecular geneticist Anne Ferguson-Smith, describes as 'genetics with knobs on'. Anne, now Arthur Balfour Professor of Genetics and Pro-Vice Chancellor for Research at the University of Cambridge, tells Jim Al-Khalili about her life and work. She's spent her professional life at the cutting edge: from a degree in a brand new field of Molecular Biology, to post-grad working on brand new genetic structures, through to a lifetime of discoveries and breakthroughs which have changed our understanding of the genome. Yet she wasn't always destined to be a scientist. She says she was a 'bad student' for a lot of her early life, and believes that embracing failure is an essential part of being a working scientist. (Image: Anne Ferguson Smith. Credit: Anne Ferguson Smith)

From landslides and wildfires to floods and tornadoes, Bruce Malamud has spent his career travelling the world and studying natural hazards. Today, he is Wilson Chair of Hazard and Risk and executive director of the Institute of Hazard, Risk and Resilience at Durham University - but as he tells Jim al-Khalili, a lifelong passion for discovery has taken Bruce from volunteering with the Peace Corps in West Africa and a Fulbright Fellowship in Argentina, to fieldwork in India; not only studying hazards themselves, but also the people they affect - and building up the character and resilience to overcome personal tragedy along the way. Over the years, his work in the field has opened up new ways of understanding such events: from statistical modelling to show how groups of hazards occur, to examining the cascading relationships between multiple hazards. And today, his focus is on projects that can bring tangible benefits to people at serious risk from environmental hazards - finding innovative ways to help them to better manage that threat. (Photo: Bruce Malamud. Credit: Bruce Malamud)

The world around us is three-dimensional. Yet, there are materials that can be regarded as two-dimensional. They are only one layer of atoms thick and have remarkable properties that are different from their three-dimensional counterparts. Sir Andre Geim created the first-ever man-made 2D material, by isolating graphene, and is one of the pioneers in this line of research. Even beyond his Nobel Prize-winning work on graphene, he has explored new ideas in many different areas of physics throughout his career. Andre tells Jim al-Khalili about his time growing up in the Soviet Union, being rejected from university based on his German ethnicity, his move to Western Europe, and levitating frogs. (Photo: 2010 Nobel Physics laureate Andre Geim during 2019 China Science Fiction Convention, Beijing, 3 November, 2019. Credit: VCG/Getty Images)

Norwegian jazz musician Jon Larsen was having breakfast one clear spring morning when he noticed a tiny black speck land on his clean, white table. With no wind, birds or planes in sight, he wondered if it fell from space. Dust from space is not as fanciful as it sounds. Billions of microscopic meteorites, dating back to the birth of our solar system, fall onto Earth every year. But they are so tiny, hidden among the copious dust of everyday life, that scientists believe they are impossible to find outside ultra clean environments like Antarctica. But this doesn’t deter Jon, who, against the advice of all experts, decides he is going to be the first person to find an urban micrometeorite. He takes presenter Caroline Steel and planetary scientist Dr Matthew Genge up onto some roofs, in search of the elusive particles. Can we find stardust on the top of the BBC? Featuring Jon Larsen, Dr Matthew Genge and Svein Aarbostad. Presenter: Caroline Steel (Image: Cygnus Nebulosity and Starclouds Credit: VW Pics / Contributor | Getty Images)

We've been building computers to think like us for years, but our ability to replicate human senses has been impossible. Until now. Evolutionary biologist and broadcaster Professor Ben Garrod, is off to meet some of the sensory innovators and technological pioneers who are developing human like-sensing technology. From skin patches that can read our sugar levels, to brain implants that could use our thoughts to control computers. This is the technology that could blur the boundary between body, mind, and computer chip. We meet Jules Howard, a zoologist who uses VR to help us explore the anatomical worlds inside animals. Jules shows us the inner-workings of a ducks vagina. We meet Anagram, who’s augmented reality experiences can visualise the inner-worlds of those experiencing schizophrenia and ADHD. We play with the health monitors and wearable tech that claim they could make us fitter, happier, and more productive humans. And meet Dr David Putrino, a clinician with Mount Sinai in New York, who’s conducting some of the first medically-approved surgery for brain implants. Presenter: Professor Ben Garrod Producer: Robbie Wojciechowski Production co-ordinator: Jonathan Harris (Image: Artificial intelligence robot and binary. Credit: Yuichiro Chino/Getty Images)

We've been building computers to think like us for years, but our ability to replicate human senses has been impossible. Until now. This technological revolution is starting to profoundly change not only how we interact with the world around us, but is allowing us to see, hear, smell, taste and even touch things we never imagined possible before. An artificial intelligence revolution is super-charging sensing technology, promising us eyes with laser precision, ears that can distinguish every sound in a mile's radius and noses than can sniff out the early signs of forest fires before the first flame forms. Evolutionary biologist and broadcaster Professor Ben Garrod is off to meet some of these sensory innovators and technological pioneers - the programmers, robotics engineers and neuroscientists, who are turning our world upside down and inside out. In episode four - we’ll explore touch and what role does it plays for our nearest living relatives. Ben tries to give his mum a hug from 5,000 miles away. We discover what brain scans show when Ben given both painful and pleasurable touch. We explore what role the body could play in our use of computers in the future. We hear about remotely-operated sex toys. And learn about how all this might shift our understandings of intimate relationships in the future. Could these new technologies and natural evolutions be redefining what it is to touch? Ben takes us through the amazing adaptations, and technological developments that could help touch become digitised. Presenter: Prof Ben Garrod Producer: Robbie Wojciechowski Production Co-ordinator: Jonathan Harris (Photo: Hands touching fingers. Credit: Kelvin Murray/Getty Images)

In The Evidence on the BBC World Service, Claudia Hammond will be exploring the concept of solastalgia; broadly defined as the pain or emotional suffering brought about by environmental change close to your home or cherished place. Made in collaboration with Wellcome Collection, Claudia Hammond and an expert panel examine this relatively new concept, one that might be increasingly heard about as the effects of climate change are felt. Claudia will be hearing stories of solastalgia from communities in Kenya and Indonesia and examining where storytelling fits in with other types of evidence when it comes to health and wellbeing. What kind of impact can personal stories of loss have on policy makers? On stage with Claudia and in front of a live studio audience, are artist Victoria Pratt, Creative Director of Invisible Flock; Daniel Kobei, Director of Ogiek People’s Development Program; epidemiologist Dr Elaine Flores from the Centre on Climate Change and Planetary Health at the London School of Hygiene and Tropical Medicine; former prime minister of Australia Julia Gillard and environmental activist Laetania Belai Djandam Produced by: Helena Selby and Geraldine Fitzgerald Studio Engineers: Emma Harth and Duncan Hannant Photo: Man standing in grey climate whilst looking towards bright climate. Credit: Getty Images.

We've been building computers to think like us for years, but our ability to replicate human senses has been impossible. Until now. This technological revolution is starting to profoundly change not only how we interact with the world around us, but is allowing us to see, hear, smell, taste and even touch things we never imagined possible before. An artificial intelligence revolution is super-charging sensing technology, promising us eyes with laser precision, ears that can distinguish every sound in a mile's radius and noses than can sniff out the early signs of forest fires before the first flame forms. Evolutionary biologist and broadcaster Professor Ben Garrod, is off to meet some of these sensory innovators and technological pioneers. The archaeologists, ecologists and medics, who are turning our world upside down and inside out. Could these new technologies and natural evolutions be redefining what it is to smell? Ben takes us through the amazing adaptations, and technological developments that could help broaden how we think of our noses. Presenter: Professor Ben Garrod Producer: Robbie Wojciechowski Production co-ordinator: Jonathan Harris (Photo: Close up of human nose smelling an animated smell. Credit | Getty Images)

We've been building computers to think like us for years, but our ability to replicate human senses has been impossible. Until now. This technological revolution is starting to profoundly change not only how we interact with the world around us, but is allowing us to see, hear, smell, taste and even touch things we never imagined possible before. An artificial intelligence revolution is super-charging sensing technology, promising us eyes with laser precision, ears that can distinguish every sound in a mile's radius and noses that can sniff out the early signs of forest fires before the first flame forms. Evolutionary biologist and broadcaster Professor Ben Garrod is off to meet some of these sensory innovators and technological pioneers; The archaeologists, ecologists and medics, who are turning our world upside down and inside out. In episode two, Ben finds sound solutions to tricky problems. We’ll hear about the ear which works up to depths of 500m below the ocean. In this light-deprived oceanic environment, we’ll find out how sound has become the most important sense. We’ll learn how noise pollution has inspired a number of revolutionary scientists to create sound-based solutions to better animal conservation. Along the way, we’ll meet engineers and computer programmers who’ve been able to find animals we thought previously extinct, and learn how one colour blind ornithologist mapped the entirety of a Caribbean archipelago so he could help protect his favourite species from storms and freak climate events. Could these new technologies and natural evolutions be redefining what it is to hear? Ben takes us through the amazing adaptations and technological developments that could help stretch our hearing further than ever before. Produced by Robbie Wojciechowski Presented by Professor Ben Garrod Production Coordinator: Jonathan Harris (Photo: Field mouse with large ears. Credit: Zoological Society of London/PA Wire)

We've been building computers to think like us for years, but our ability to replicate human senses has been impossible. Until now. This technological revolution is starting to profoundly change not only how we interact with the world around us, but is allowing us to see, hear, smell, taste and even touch things we never imagined possible before. An Artificial Intelligence revolution is super-charging sensing technology, promising us eyes with laser precision, ears that can distinguish every sound in a mile radius and noses than can sniff out the early signs of forest fires before the first flame forms. Evolutionary biologist and broadcaster Prof Ben Garrod, is off to meet some of these sensory innovators and technological pioneers. The archaeologists, ecologists and medics, who are turning our world upside down and inside out. In episode one, Ben tries seeing further. The visible world to us is tiny, and we are able to detect just a fraction of the light spectrum that is out there. But new technology is pushing the boundary of what is visible. Ground penetrating LIDAR arrays are helping us to peel back the layers of planet Earth, and see the remains of ancient civilisations, previously invisible to us. The same technology is being used on the moons of Jupiter to provide 3D maps of the craters of faraway worlds. In the forests of west Africa, we meet the psychologists using infrared to monitor the stress levels of silverback gorillas being returned to the wild. And in a lab in central London, we meet the extraordinary animals that see hidden patterns in the natural world and perhaps even fields that are entirely invisible to us. Could these new technologies be redefining what it is to see, hear, smell, and feel? Ben takes us through the amazing adaptations and development under the bonnet, and speculates where else these all seeing eyes may yet gaze. Presenter: Professor Ben Garrod Producer: Robbie Wojciechowski Production co-ordinator: Jonathan Harris (Image: Concept illustration of eye seen through clouds. Credit: Hans Neleman/Getty Images)

James Gallagher get's behind the hype to find out if sperm counts are really falling? There are plenty of headlines telling us they are, but also scientists who disagree - he unpicks the evidence with two of them. James also gets his own sperm sample analysed and meets a couple who found the reason behind their low count was one of the leading causes of male infertility.

James Gallagher reports on a psychedelic renaissance; a new wave of research testing hallucinogenic drugs like magic mushrooms to treat mental health conditions. There’s genuine excitement and some early encouraging evidence. A manufacturer tells James that in five years’ time, it’s possible that psychedelics could be part of the medicine cabinet – but with the hype, there’s risk too and there’s much still to learn about who these drugs could help and how. Presenter: James Gallagher Producer: Geraldine Fitzgerald Image: Fungi on purple background. Credit: Getty Images.

We are familiar with fungal infections like Thrush and Athlete’s Foot, but fungal diseases that can kill are on the increase. The World Health Organisation is so concerned that it has published its first ever list of life threatening fungi. James Gallagher hears stories of hospitals being shut down, a ruined honeymoon and fungal infections that consume human tissue leaving terrible disfigurement. Add to that The Last of Us, a hit video game turned TV series where a parasitic fungus manipulating the brains of ants has jumped to people. Sounds fanciful but while this particular fungus could not cross from ants to humans, Dr Neil Stone explains why invasive fungal infections are on the rise and a potential pandemic should not be dismissed.

Soaring food prices mean putting food on the table is a daily struggle. This is the grim reality for millions around the world. But hunger, so long a feature in lower-income countries, is becoming a familiar picture in richer ones too. James Gallagher reports from the UK, one of the wealthiest countries in the world, where food prices are rising at the fastest rate for 45 years and millions are turning to charity to feed themselves and their families. He visits the charities which help people to continue to eat and cook healthy food and hears from Professor Sir Michael Marmot from University College London, who has spent a lifetime researching the consequences of inequality and poverty. Food insecurity, he tells James, damages the health of children and adults.

After centuries of use in wound-healing, the maggot is back. The rise of the drug-resistant superbug means fresh eyes are focused on the superpowers of the larvae of the greenbottle fly species, Lucilia Sericata. James Gallagher reports on the healthcare professionals who are turning to maggot therapy to help clean up wounds and stop infection. He talks to Melanie who has Type 1 Diabetes and had a quarter of her foot amputated. When the skin around the wound started to die, threatening the whole limb, she was offered maggot therapy. Now a self-declared maggot superfan, Melanie watched as the larvae, inside a bag a bit like a teabag, digested the dead skin on her foot. And James visits a factory in Wales, BioMonde, preparing medical grade fly eggs for use across the UK health service. (Photo: Larvae of the greenbottle fly sitting on so-called horse blood agar seen through a magnifying glass at the pharmaceutical company BioMonde. Credit: David Hecker/DDP/AFP/Getty Images)

James Gallagher is on a mission to find out what is the least amount of exercise you can do to still stay healthy. James goes on a Ramblers wellbeing walk, uses a treadmill for the first time and takes a hot bath all to find out how lazy he can be and still gain some health benefits. (Photo: James Gallagher on a treadmill. Credit: Emma Lynch)

There is a bizarre number in maths referred to simply as ‘i’. It appears to break the rules of arithmetic - but turns out to be utterly essential for applications across engineering and physics. We are talking about the square root of -1, which makes no sense. Professor Fry waxes lyrical about the beauty and power of this so-called ‘imaginary’ number to a sceptical Dr Rutherford. Dr Michael Brooks, author of The Maths That Made Us, tells the surprising story of the duelling Italian mathematicians who gave birth to this strange idea, and shares how Silicon Valley turned it into cold hard cash. Professor Jeff O’Connell, Ohlone College California, demonstrates that it is all about oscillations, and Dr Eleanor Knox, philosopher of physics at KCL and a senior visiting fellow at the University of Pittsburgh reveals that imaginary numbers are indispensable for the most fundamental physics of all - quantum mechanics.

This episode will render you oblivious, conked out and blissfully unaware. It’s about anaesthetics: those potent potions that send you into a deep, deathly sleep. Listener Alicia wants to know how they work, so our sleuths call on the expertise of consultant anaesthetist Dr Fiona Donald. Fiona shares her experience from the clinical frontline, and explains what we do and don’t know about how these chemicals work their mind-numbing magic. We hear about ground-breaking research led by Professor Irene Tracey, which reveals how a pattern of slow brain waves can be used to determine the optimum dosage of these dangerous drugs. And finally, Drs Rutherford and Fry wonder: what does all this tell us about normal consciousness? Professor Anil Seth shares how we can use brain tech to measure different levels of conscious awareness – from sleepy to psychedelic.

‘Can we bring back extinct species?’ wonders listener Mikko Campbell. Well, Professor Fry is pretty excited by the prospect of woolly mammoths roaming the Siberian tundra once more. And everyone is impressed with the science that might make it happen. But Dr Rutherford comes out STRONGLY against the whole thing. Can our expert guests win him over? Dr Helen Pilcher shares the tale of Celia the lonely mountain goat, and makes the case for cloning to help protect species at risk of extinction. Professor Beth Shapiro sets out how biotech company ‘Colossal’ plans to engineer Asian elephants’ DNA to make a new group of mammoth-like creatures. And we hear how genetic technologies are being used in conservation efforts around the world. BUT WHAT ABOUT T-REXES? Not gonna happen. Sorry. Contributors: Dr Helen Pilcher, author of ‘Bring Back the King: The New Science of De-Extinction’, Professor Beth Shapiro from the University of California Santa Cruz, Dr Ben Novak of Revive and Restore and Tullis Matson from Nature’s SAFE.

The Great Pyramids of Giza are awesome feats of engineering and precision. So who built them - and how? Was it a mysteriously super-advanced civilization now oddly extinct? Was it even aliens? Nah, course not! Rutherford and Fry investigate how these inspiring monuments were really constructed, and learn about the complex civilisation and efficient bureaucracy that made them possible. Professor Sarah Parcak busts the myth that they were built by slaves. In fact, she reveals, it was gangs of well-paid blokes fuelled by the ancient Egyptian equivalent of burgers and beer. And Dr Chris Naunton explains how it was not some mysterious tech, but incredible organisation and teamwork which made it possible to transport massive stone blocks over long distances several thousand years before trucks arrived. Dr Heba Abd El Gawad points out how racism led to bizarre assumptions in the history of archaeology, and how those assumptions linger in contemporary conspiracy theories which refuse to accept that Egyptians could have built the pyramids themselves! Contributors: Professor Sarah Parcak, University of Alabama, Dr Chris Naunton, Egyptologist and broadcaster, Dr Heba Abd El Gawad, University College London

Close your eyes and think of a giraffe. Can you see it? I mean, *really* see it - in rich, vivid detail? If not - you aren’t alone! We’ve had scores of messages from listeners who report having a ‘blind mind’s eye’. They don’t see mental images at all and they want to know why. Jude from Perth wants to know what makes her brain different, and Diane from Scotland wonders whether it affectes her ability to remember family holidays. Our sleuths learn that this is a condition recently termed ‘aphantasia’. They meet the chap who came up with the name, Professor Adam Zeman, a neurologist from the University of Exeter, and quiz him on the brain mechanisms behind this mystery. Professor Julia Simner - a psychologist who, herself, doesn’t see mental images - shares the surprising research into how aphants differ slightly from others in a range of cognitive skills. We also hear about the world class artists and animators who can’t visualise - but can create beautiful, imaginary worlds. Philosophy professor Fiona Macpherson from the University of Glasgow, deepens the mystery: perhaps this largely hidden phenomenon is behind some of the most profound disagreements in the history of psychology. Our mental experiences are all very different - maybe that’s why thinkers have come up with such different theories about how our minds work. Search for the “VVIQ” or Vividness of Visual Imagery questionnaire to take the test yourself. Look for “The Perception Census” to take part in this massive online study of perceptual variation. And look up the 'Aphtantasia Network' if you're curious to find out more. Presenters: Hannah Fry and Adam Rutherford Contributors: Professor Adam Zeman, Professor Julia Simner, Professor Fiona Macpherson

We are a teeming mass of interconnected microbes and the impact of this microscopic universe on our health, our minds, even our moods, is profound. Made in collaboration with Wellcome Collection, Claudia Hammond and an expert panel explore one of the fastest moving areas of science and what it means for modern medicine. Recorded in front of a live audience at Wellcome’s Reading Room in London, Claudia discovers how our microbes could be harnessed to improve our mental and physical health. And along with the scientific insights, there are important answers to questions everybody wants to know the answer to, such as why some peoples’ “emissions” smell so badly and how having a dog or cat enriches your microbiome. On stage with Claudia are immunologist Professor Sheena Cruickshank from the University of Manchester, microbiologist Professor Glenn Gibson from the University of Reading and neuroscientist Professor John Cryan from University College Cork in Ireland. Produced by: Fiona Hill and Elisabeth Tuohy Studio Engineer: Bob Nettles and Emma Hearth Image: Scanning electron micrograph (SEM) of bacteria cultured from a sample of human faeces. Credit: Steve Gschmeissner/Science Photo Library/Getty Images

Think Sahara Desert, think intense heat and drought. We see the Sahara as an unrelenting, frazzling, white place. But geo-archaeologist Dr Judith Bunbury says in the not so distant past, the region looked more like a safari park. In the more recent New Kingdom of Ancient Egypt, from around 3500 years ago (the time of some of Egypt’s most famous kings like Ahmose I, Thutmose III, Akhenaten, Tutankhamun and queens like Hatshepsut) core samples shows evidence of rainfall, huge lakes, springs, trees, birds, hares and even gazelle, very different from today. By combining geology with archaeology, Dr Bunbury, from the department of Earth Sciences at the University of Cambridge and Senior Tutor at St Edmund’s College, tells Jim al-Khalili that evidence of how people adapted to their ever-changing landscape is buried in the mud, dust and sedimentary samples beneath these ancient sites, waiting to be discovered. The geo-archaeological research by Judith and her team, has helped to demonstrate that the building of the temples at Karnak near Luxor, added to by each of the Pharaohs, was completely dependent on the mighty Nile, a river which, over millennia, has wriggled and writhed, creating new land on one bank as it consumes land on another. Buildings and monuments were adapted and extended as the river constantly changed course.

Clifford Johnson's career to date has spanned some seemingly very different industries - from exploring quantum mechanics around string theory and black holes, to consulting on some of Hollywood's biggest movies; but it makes sense once you understand his ambition of making science accessible to all. A Professor in the Department of Physics and Astronomy at the University of Southern California in Los Angeles, Clifford's worked in the United States for decades – but was born in the UK, then spent his formative years on the Caribbean island of Montserrat, before moving back to England to study. Here, he fell in love with quantum mechanics - before moving to the US, where he's broken new ground in finding ways to talk about quantum gravity and black holes. Clifford's other big passion is getting as many people as possible engaged with science, making it more exciting, entertaining and most importantly diverse - and it's this attitude that's led to regular work as a science consultant on various TV shows and films; and even a recent cameo in a major movie.

A fur-stripped mouse carcase might not sound like the cosiest of homes – but that is where the burying beetle makes its nest, and where Rebecca Kilner has focused much of her research. A professor of evolutionary biology at the University of Cambridge, Rebecca’s work – initially with cuckoos, then more recently with beetles – has shed invaluable light on the relationship between social behaviours and evolution. She tells Jim al-Khalili how the beetles' helpfully swift generational churn and mouse-based parenting has allowed her team to study evolution in action, demonstrating for the first time what was previously just evolutionary theory.

Magnets are inside loads of everyday electronic kit - speakers, motors, phones and more - but listener Lucas is mystified. What, he wonders, is a magnetic field? Our sleuths set out to investigate the mysterious power of magnets, with the help of wizard physicist Dr Felix Flicker, lecturer in physics at Cardiff University and author of the The Magick of Matter, and materials scientist Dr Anna Ploszajski, author of Handmade. They cover the secrets of lodestones, naturally occurring magnetic rocks, how to levitate crystals, frogs and maybe even people. Matthew Swallow, the Chair of the UK Magnetics Society, explains why magnets make the best brakes for rollercoasters, and Dr Ploszajski explains how magnetically-induced eddy currents are used to sort through our recycling. Finally, Dr Flicker persuades Adam and Hannah that to really understand magnetic fields you have to leave classical physics behind, and go quantum. So our sleuths take a leap into the strange subatomic realm.

Tim Lamont is a young scientist making waves. Arriving on the Great Barrier Reef after a mass bleaching event, Tim saw his research plans disappear and was personally devastated by the destruction. But from that event he discovered a novel way to restore coral reefs. Playing the sounds of a healthy coral reef entices fish in to recolonise the wrecked reefs. Tim's emotional journey forced him to realise that environmental scientists can no longer just observe. They need to find new prisms with which to view the world and to intervene to save or protect the natural environment.

Are we entering a ‘newgenic’ age - where cutting-edge technologies and the power of personal choice could achieve the kind of genetic perfection that 20th century eugenicists were after? In 2018, a Chinese scientist illegally attempted to precision edit the genome of two embryos. It didn’t work as intended. Twin sisters - Lulu and Nana - were later born, but their identity, and the status of their health, is shrouded in secrecy. They were the first designer babies. Other technological developments are also coming together in ways that could change reproduction: IVF can produce multiple viable embryos, and polygenic screening could be used to select between them. Increased understanding and control of our genetics is seen as a threat by some - an inevitable force for division. But instead of allowing genetics to separate and rank people, perhaps there’s a way it can be used - actively - to promote equality. Professor Paige Harden shares her suggestion of an anti-eugenic politics which makes use of genetic information Contributors: Dr Helen O'Neill, lecturer in Reproductive and Molecular Genetics at University College London, Dr Jamie Metzl, author of Hacking Darwin, Professor Kathryn Paige Harden from the University of Texas and author of The Genetic Lottery: Why DNA Matters for Social Equality.

In the mid-19th Century, an Augustinian friar called Gregor Mendel made a breakthrough. By breeding pea plants and observing how certain traits were passed on, Mendel realised there must be units - little packets - of information determining characteristics. He had effectively discovered the gene. His insights inspired eugenicists from the 1900s onwards. If traits were passed on by specific genes, then their policies should stop people with ‘bad’ genes from having children. Mendel’s ideas are still used in classrooms today - to teach about traits like eye colour. But the eugenicists thought Mendel's simple explanations applied to everything - from so-called ‘feeblemindedness’ to criminality and even pauperism. Today, we recognise certain genetic conditions as being passed on in a Mendelian way. Achondroplasia - which results in short stature - is one example, caused by a single genetic variant. We hear from Professor Tom Shakespeare about the condition, about his own decision to have children despite knowing the condition was heritable - and the reaction of the medical establishment. We also explore how genetics is taught in schools today and the danger of relying on Mendel’s appealingly simple but misleading account. Contributors include Dr Brian Donovan, senior research scientist at BSCS, Prof Tom Shakespeare, disability researcher at London School of Hygiene and Tropical Medicine, and Dr Christine Patch, principal staff scientist in Genomic Counselling in the Society and Ethics Research group, part of Wellcome Connecting Science. (Photo: Johann Gregor Mendel (1822-1884). Austrian botanist, followed breeding experiments, discovered paired units of heritable characteristics. Credit: Hulton Archive/Getty Images)

In the name of eugenics, the Nazi state sterilised hundreds of thousands against their will, murdered disabled children and embarked on a programme of genocide. We like to believe that Nazi atrocities were a unique aberration, a grotesque historical outlier. But it turns out that leading American eugenicists and lawmakers like Madison Grant and Harry Laughlin inspired many of the Nazi programmes, from the mass sterilisation of those deemed ‘unfit’ to the Nuremberg laws preventing the marriage of Jews and non-Jews. Indeed, before World War Two, many eugenicists across the world regarded the Nazi regime with envious admiration. The Nazis went further, faster than anyone before them. But ultimately, the story of Nazi eugenics is one of international connection and continuity. With contributions from Prof Stefan Kühl from the University of Bielefield, Prof Amy Carney from Penn State Behrend, Dr Jonathan Spiro from Castleton University, Prof Sheila Weiss from Clarkson University and Dr Barbara Warnock from the Wiener Holocaust Library (Photo: German women carrying children of an alleged aryan purity in a Lebensborn selection centre, births by eugenicists methods during World War Two. Credit Keystone-France Getty Images)

Who should be prevented from having children? And who gets to decide? Across 20th century America, there was a battle to control birth - a battle which rages on to this day. In 1907, the state of Indiana passed the first sterilisation law in the world. Government-run institutions were granted the power to sterilise those deemed degenerate - often against their will. In the same period, women are becoming more educated, empowered and sexually liberated. In the Roaring Twenties, the flappers start dancing the Charleston and women win the right to vote. But contraception is still illegal and utterly taboo. The pioneering campaigner Margaret Sanger, begins her decades long activism to secure women access to birth control - the only way, she argues, women can be truly free. In the final part of the episode, sterilisation survivor and campaigner Elaine Riddick shares her painful but remarkable story. Contributors: Professor Alexandra Minna Stern from the UCLA Institue of Society and Genetics, Professor Wendy Kline from Purdue Univerity, Elaine and Tony Riddick from the Rebecca Project for Justice Featuring the voice of Joanna Monro (Photo: Elaine Riddick was sterilised without her consent, when she was 14, in North Carolina. Credit: Tami Chappell/The Washington Post/Getty Images)

"You will not replace us" was the battle cry of white supremacists at a rally in Charlottesville in 2017. They were expressing an old fear - the idea that immigrants and people of colour will out-breed and replace the dominant white 'race'. Exactly the same idea suffused American culture in the first decades of the 1900s, as millions of immigrants arrived at Ellis island from southern and eastern Europe. The 'old-stock' Americans - the white elite who ruled industry and government - latched on to replacement theory and the eugenic idea of 'race suicide'. It's all there in The Great Gatsby - F.Scott Fitzgerald's novel set in 1922 - which takes us into the world of the super-rich, their parties and their politics. Amidst this febrile period of cultural and economic transformation, the Eugenics Record Office is established. Led by Charles Davenport and Harry Laughlin, it becomes a headquarters for the scientific and political advancement of eugenics. By 1924, the eugenically informed anti-immigrant movement has triumphed - America shut its doors with the Johnson-Reed Act, and the flow of immigrants is almost completely stopped. Contributors: Dr Thomas Leonard, Professor Sarah Churchwell, Professor Joe Cain Presenter: Adam Rutherford Producer: IIan Goodman (Photo: Immigrants arriving in Ellis Island, New York, 27 May 1920. Credit: Getty Images) Clips: BBC News, coverage of Charlottesville protests, 2017 / CNN, coverage of buffalo shooter, 2022 / MSNBC, coverage of buffalo shooter, 2022 / Edison, Orange, N.J, 1916, Don't bite the hand that's feeding you, Jimmie Morgan, Walter Van Brunt, Thomas Hoier / BBC Radio 4 Great Gatsby: Author, F Scott Fitzgerald Director: Gaynor Macfarlane, Dramatised by Robert Forrest.

We follow the story of eugenics from its origins in the middle-class salons of Victorian Britain, through the Fitter Family competitions and sterilisation laws of Gilded Age USA, to the full genocidal horrors of Nazi Germany. Eugenics is born in Victorian Britain, christened by the eccentric gentleman-scientist Sir Francis Galton. It’s a movement to breed better humans, fusing new biological ideas with the politics of empire, and the inflexible snobbery of the middle-classes. The movement swiftly gains momentum - taken up by scientists, social reformers, and even novelists as a moral and political quest to address urgent social problems. By encouraging the right people to have babies, eugenicists believed we could breed ourselves to a brighter future; a future free from disease, disability, crime, even poverty. What, its proponents wondered, could be more noble? The story culminates in the First International Eugenics Congress of 1912, where a delegation of eminent public figures from around the world gather in South Kensington to advocate and develop the science – and ideology – of better breeding. Among them Winston Churchill, Arthur Balfour, the Dean of St Pauls, Charles Darwin's son, American professors and the ambassadors from Norway, Greece, and France. But amidst the sweeping utopian rhetoric, the darker implications of eugenic ideas emerge: what of those deemed 'unfit'? What should happen to them? Contributors: Professor Joe Cain, Daniel Maier, Professor Philippa Levine, Professor Angelique Richardson Featuring the voices of David Hounslow, Joanna Monro and Hughie O'Donnell (Photo: Francis Galton (1822-1911), British man of science born in Sparkbrook (England). Ca. 1890. Credit: adoc-photos/Corbis/Getty Images)

Hiding in the shadows across the American continents lives a big cat with many names. From puma to mountain lion to panther to cougar, this animal is carnivorous, cunning and uses stealth to silently ambush its prey. Its elusiveness and brutal attacking style has earnt it the reputation of a cold-hearted killer. But behind this façade, hidden camera footage has revealed the cougar is all about caring for their family. And its silent whispering amongst the trees could actually be saving human lives. Adam Hart and guests uncover the mysteries of the ‘ghost of the forest’ and break its merciless stereotype. Dr Laura Prugh, associate Professor of Quantitative Wildlife Sciences at the University of Washington, and Dr Mark Elbroch, ecologist and director of the Panthera programme in Washington USA.

Why do wasps exist? While many see them as unfriendly bees who sting out of spite, their aggression could be interpreted as a fierce form of family protection. They are hugely understudied and even more underappreciated, with hundreds of thousands of different species carrying out jobs in our ecosystems. Some live together in nests whereas others hunt solo, paralysing prey with antibiotic-laden venom. In abundance, they can destroy environments - outcompeting most creatures and taking resource for themselves - but could we harness their predatory powers to take on pest control? Adam Hart and guests are a-buzz about this much-maligned insect and explore why we should be giving them more credit. Professor Seirian Sumner, behavioural ecologist at University College London, and Dr Jenny Jandt, ecologist at University of Otago, New Zealand.

As a great African predator and a hot-spot on safari, it is hard to believe that only last century, the African wild dog was considered vermin. It's beautiful coat of painted strokes makes it undeniably distinctive. Yet out in the field, this animal is hard to find. Yes, it camouflages easily against the landscape, but years of persecution, bounties and unintentional trappings means it's now one of the most endangered mammals on the planet. Revelations about its reliance on the pack for protection, predation and parenting means every dog matters in its bid for survival. So how can we further stop numbers dwindling? Adam Hart and guests investigate the tools and tales of the magnificent painted wolf. Dr Dani Rabaiotti, zoologist at the Zoological Society of London, and David Kuvawoga and Jealous Mpofu, conservationists at Painted Dog Conservation in Zimbabwe.

Infectious diseases which cause epidemics and pandemics are on the rise. Claudia Hammond is joined by an eminent panel of disease detectives, who spell out why the risks are increasing and most importantly, what we can do to predict, prepare and protect ourselves against potentially devastating new outbreaks. Will the next infectious disease to wreak havoc across the globe again jump from animals, a zoonotic jump across species? Think SARS, HIV, MERS, Zika, Nipah Virus, Lassa Fever, Ebola, Avian Flu, Swine Flu, Mpox and of course the coronavirus that causes Covid-19. The panel is unanimous in their plea for recognition that human health is inextricably linked to both animal health and the health of the environment. Without an understanding that we are part of an ecosystem and that climate change and the loss of biodiversity have a direct impact on epidemic and pandemic risk, we’ll struggle to keep ourselves safe they say. Claudia is joined by vet-turned-virologist Marion Koopmans, Professor of Viroscience at Erasmus Medical Centre in the Netherlands and head of the Pandemic and Disaster Preparedness Centre; by Tulio de Oliveira, Professor of Bioinformatics, director of the Centre for Epidemic Response and Innovation (CERI) and the KwaZulu-Natal Research Innovation and Sequencing Platform (KRISP) in South Africa and Malik Peiris, Professor of Virology at the University of Hong Kong’s School of Public Health. Produced by: Fiona Hill and Elisabeth Tuohy Studio Engineer: Duncan Hannant Image: Chickens in Thailand Credit: Wut'hi Chay Si Tang Kha/EyeEm/Getty Images

With nicknames like ‘prehistoric monster’ and ‘living dinosaur’, the Komodo dragon has been well and truly judged by its cover. Its gigantic size, razor sharp teeth and deadly attacking power has earned it a vicious reputation. But beneath the scales of this solitary beast are fascinating tales of rapid healing, decoy nests, and virgin births. And as climate change threatens its native Indonesia, can this hostile reptile adapt to living in closer quarters? Adam Hart and guests dig into how a lonely life may be putting the Komodo dragon at risk... Deni Purwandana, program co-ordinator for the Komodo Survival Program in Komodo National Park, and Dr Chris Michaels, team leader of Reptiles and Amphibians at London Zoo.

Alpacas may have been domesticated for thousands of years but their native lands are the steep hostile mountains of South America where they continue to thrive far from the modern luxuries of animal husbandry. Prof Ben Garrod and Dr Jess French delve deep inside this hardy herbivore to unravel the anatomy and physiology that’s secured the success of this extraordinary member of the camelid family of camels, llamas and vicugna.

Prof Ben Garrod and Dr Jess French get under the skin of the harbour porpoise to unravel this enigmatic and shy aquatic mammal’s extraordinary survival skills - from it’s ability to dive for long periods to accurately echolocating its fast moving prey. They join Rob Deaville, project leader for the Cetacean’s Stranding Investigations Programme at ZSL (Zoological Society of London) to open up and examine what makes this animal unique in terms of its anatomy, behaviour and evolutionary history.

One of the world’s large owls by length, the Great Grey Owl is an enigmatic predator of coniferous forests close to the Arctic tundra. It's most often seen hunting around dawn and dusk, when it perches silently at the edges of clearings. But as Prof Ben Garrod and Dr Jess French delve deep inside to understand its true secret to survival, they find the deep feathery coat belies a deceptively small head and body that‘s evolved unbelievably powerful abilities to silently detect and ambush unsuspecting prey.

Zoologist Ben Garrod and veterinary surgeon Jess French delve deep into some amazing internal anatomy to unravel the secrets to survival of some of nature’s iconic animals. They begin with one of the rarities of the cat family – the cheetah, which at just under two metres long, is the world’s fastest land animal capable of reaching speeds of up to 70mph in three seconds. As Ben and Jess reveal, the body’s rear muscles, large heart and nostrils enable it to achieve record breaking accelerations. But over long distances, it risks total exhaustion and predation from larger carnivores and the risk of losing its valuable prey. We hear during the course of this intricate dissection, how it treads a fine line between speed and stamina in the quest for survival.

What do you get if you smash two hydrogen nuclei together? Helium and lots of energy – it's nuclear fusion! Nuclear fusion is the power source of the sun and the stars. Physicists and engineers here on earth are trying to build reactors than can harness fusion power to provide limitless clean energy. But it’s tricky. Rutherford and Fry are joined by Dr Melanie Windridge, plasma physicist and CEO of Fusion Energy Insights, who explains why the fourth state of matter – plasma – helps get fusion going, and why a Russian doughnut was a key breakthrough on the path to fusion power. Dr Sharon Ann Holgate, author of Nuclear Fusion: The Race to Build a Mini Sun on Earth, helps our sleuths distinguish the more familiar nuclear fission (famous for powerful bombs) from the cleaner and much less radioactive nuclear fusion. And plasma physicist Dr Arthur Turrell, describes the astonishing amount of investment and innovation going on to try and get fusion power working at a commercial scale.

Sneezes, wheezes, runny noses and red eyes - this episode is all about allergies. An allergic reaction is when your immune system reacts to something harmless – like peanuts or pollen – as if it was a parasitic invader. It’s a case of biological mistaken identity. Professor Judith Holloway from the University of Southampton guides our sleuths through the complex immune pathways that make allergies happen and tells the scary story of when she went into anaphylactic shock from a rogue chocolate bar. Professor Adam Fox, a paediatric allergist at Evelina Children’s Hospital, helps the Drs distinguish intolerances or sensitivities – substantial swelling from a bee sting, for example - from genuine allergies. Hannah’s orange juice ‘allergy’ is exposed as a probable fraud! Hannah and Adam explore why allergies are on the increase, and Professor Rick Maizels from the University of Glasgow shares his surprising research using parasitic worms to develop anti-allergy drugs! Contributors: Professor Judith Holloway, Professor Adam Fox, Professor Rick Maizels

Pi is the ratio between a circle’s diameter and its circumference. Sounds dull – but pi turns out to have astonishing properties and crop up in places you would never expect. For a start, it goes on forever and never repeats, meaning it probably contains your name, date of birth, and the complete works of Shakespeare written in its digits. Maths comedian Matt Parker stuns Adam with his ‘pie-endulum’ experiment, in which a chicken and mushroom pie is dangled 2.45m to form a pendulum which takes *exactly* 3.14 seconds per swing. Mathematician Dr Vicky Neale explains how we can be sure that the number pi continues forever and never repeats - despite the fact we can never write down all its digits to check! She also makes the case that aliens would probably measure angles using pi because it’s a fundamental constant of the universe. Nasa mission director Dr Marc Rayman drops in to explain how pi is used to navigate spacecraft around the solar system. And philosopher of physics Dr Eleanor Knox serves up some philoso-pi, revealing why some thinkers have found pi’s ubiquity so deeply mysterious.

Why are some smells so nasty and others so pleasant? Rutherford and Fry inhale the science of scent in this stinker of an episode. Our sleuths kick off with a guided tour of the airborne molecules and chemical receptors that power the sense of smell. Armed with a stack of pungent mini-flasks, professor Matthew Cobb from the University of Manchester shows Hannah and Adam just how sensitive olfaction can be, and how our experience of some odours depends on our individual genetic make-up. Dr Ann-Sophie Barwich from Indiana University reveals how most everyday smells are complex combinations of hundreds of odorants, and how the poo-scented molecule of indole turns up in some extremely surprising places. With the help of a flavoured jellybean and some nose clips, Hannah experiences how smell is crucial to flavour, adding complexity and detail to the crude dimensions of taste. Speaking of food, listener Brychan Davies is curious about garlic and asparagus: why do they make us whiff? Professor Barry Smith from the Centre for the Study of the Senses reveals it's down to sulphur-containing compounds, and tells the story of how a cunning scientist managed to figure out the puzzle of asparagus-scented urine. Finally, another listener Lorena Busto Hurtado wants to know whether a person’s natural odour influences how much we like them. Barry Smith says yes - we may sniff each other out a bit like dogs - and cognitive neuroscientist Dr Rachel Herz points to evidence that bodily bouquet can even influence sexual attraction!

How do winds start and why do they stop? asks Georgina from the Isle of Wight. What's more, listener Chris Elshaw is suprised we get strong winds at all: why doesn't air just move smoothly between areas of high and low pressure? Why do we get sudden gusts and violent storms? To tackle this breezy mystery, our curious duo don their anoraks and get windy with some weather experts. Dr Simon Clark, a science Youtuber and author of Firmament, convinces Adam that air flow is really about the physics of fluids, which can all be captured by some nifty maths. The idea of pressure turns out to be key, so Hannah makes her own barometer out of a jar, a balloon and some chopsticks, and explains why a bag of crisps will expand as you walk up a mountain. Professor Liz Bentley, Chief Executive of the Royal Meteorological Scoiety, reveals how the dynamics of a simple sea breeze – where air over land is heated more than air over water – illustrates the basic forces driving wind of all kinds. Then everyone gets involved to help Adam understand the tricky Coriolis effect and why the rotation of the Earth makes winds bend and storms spin. And Professor John Turner from the British Antarctic Survey explains why the distinctive features of the coldest continent make its coastline the windiest place on earth.

DO WE HAVE YOUR ATTENTION? Good! But how does that work!? Our intrepid science sleuths explore why some things immediately catch your eye - or ear - while others slip by totally unnoticed. Even, on occasion, basketball bouncing gorillas. Professor Polly Dalton, a psychologist who leads The Attention Lab at Royal Holloway University, shares her surprising research into ‘inattentional blindness’ - when you get so absorbed in a task you can miss striking and unusual things going on right in front of you. Dr Gemma Briggs from the Open University reveals how this can have dangerous everyday consequences: you are four times more likely to have a crash if you talk on the phone while driving -even handsfree. Drs Rutherford and Fry also hear from stroke survivor Thomas Canning, who developed the tendency to ignore everything on the left side of space, despite his vision being totally intact. And Dr Tom Manly, from the University of Cambridge’s Cognition and Brain Sciences Unit, helps our sleuths unpack the neuroscience of this fascinating condition.

Chi Onwurah tells Jim Al-Khalili why she wanted to become a telecoms engineer and why engineering is a caring profession. As a black, working class woman from a council estate in Newcastle, she was in a minority of one studying engineering at university in London and encountered terrible racism and sexism. She went on to build digital networks all over the world, the networks that make today's instant muli-media communications possible. And Chi built the first mobile phone network in Nigeria, when the country was without a reliable electricity supply. Today she is Shadow Minister for Science, Research and Innovation. When Chi decided to go into politics, her engineering colleagues were not impressed. Why would anyone leave their noble profession to enter a chaotic, disreputable and dubiously useful non-profession, they asked. But, Chi believes, parliament desperately needs more scientists and engineers, not only to help us solve science-based problems but also to create technical jobs and build a strong economy.

Six and a half million dead. More than a hundred times that infected. The Covid-19 pandemic has wreaked havoc across the globe. But in the final months of the third year of this health crisis, some now claim it’s all over. Scientists with key roles in the global response join Claudia Hammond to consider the evidence behind the declarations that the pandemic has finished and they set out how, officially, this global health crisis will be brought to an end. They reject claims that the pandemic is over, but say the emergency phase of this global health crisis is coming to a close. But only if countries remain vigilant and maintain pandemic preparedness. If vaccines reach arms, if treatments are shared equally and if nations re-introduce public health measures like mask wearing and social distancing when the inevitable new waves (and potential new variants) emerge, the appalling loss of life we saw at the beginning of the pandemic, they tell Claudia, won’t be repeated. There are stark warnings too that the dramatic global drop in the sequencing of virus samples (which enables us to see how the virus is evolving) is posing a serious risk. We can’t react to a new threat, Claudia’s panel say, if you can’t see it. Sequencing, as well as testing, has fallen by 90% since January this year, from 100,000 weekly sequences ten months ago to less than 10,000 now. This severely limits the ability to track the known variants (currently 200 sub-lineages of the Omicron variant). Produced in collaboration with Wellcome and recorded in front of a live audience in Wellcome’s Reading Room in London, Claudia’s expert panel includes Dr Maria Van Kerkhove, the World Health Organisation’s Technical Lead for Covid-19, Professor Salim Abdool Karim, co-chair of the south African Ministerial Advisory Committee on Covid-19 and a member of the Africa Task Force which oversees the African continent’s response to the virus and Professor Sir Jeremy Farrar, the Director of Wellcome and a former adviser to the UK government on its Covid response. Presenter: Claudia Hammond Produced by: Fiona Hill and Maria Simons Studio Engineers: Giles Aspen and Emma Harth

Literature student turned neuroscientist, Prof David Eagleman, tells Jim Al-Khalili about his research on human perception and the wristband he created that enables deaf people to hear through their skin. Everything we see, taste, smell, touch and hear is created by a set of electro-chemical impulses in the dark recesses of our brain. Our brains look for patterns in these signals and attach meaning to them. So in future perhaps we could learn to ‘feel’ fluctuations in the stock market, see in infra-red or echo-locate like bats? Each brain creates its own unique truth and David believes, there are no real limits to what we humans can perceive.

Nobel Prize winning chemist Frances Arnold left home at 15 and went to school ‘only when she felt like it’. She disagreed with her parents about the Vietnam war and drove big yellow taxis in Pittsburgh to pay the rent. Decades later, after several changes of direction (from aerospace engineer to bio-tech pioneer), she invented a radical new approach to engineering enzymes. Rather than try to design industrial enzymes from scratch (which she considered to be an impossible task), Frances decided to let Nature do the work. ‘I breed enzymes like other people breed cats and dogs’ she says. While some colleagues accused her of intellectual laziness, industry jumped on her ideas and used them in the manufacture of everything from laundry detergents to pharmaceuticals. She talks to Jim Al-Khalili about her journey from taxi driver to Nobel Prize, personal tragedy mid-life and why advising the White House is much harder than doing scientific research.

Who could forget the beginning of 2020, when a ‘mysterious viral pneumonia’ emerged in the Chinese city of Wuhan. Soon, other countries were affected and deaths around the world began to climb. Perhaps most alarmingly of all, there were no proven treatments to help prevent those deaths. As the World Health Organisation declared the Covid-19 outbreak a pandemic, and the UK and the rest of the world braced itself for what was to come, doctor and drug-trial designer Martin Landray had his mind on a solution, devising the protocol, or blueprint, for the world’s largest drug trial for Covid-19. As Professor of Medicine and Epidemiology at Oxford University, Martin was perfectly positioned to jump, delivering what became known as the RECOVERY Trial. The trial was tasked to deliver clarity amid the predicted chaos of the pandemic and galvanised every acute NHS hospital in the UK. Within its first one hundred days, it had yielded three major discoveries and it has transformed Covid-19 treatment worldwide, already saving over a million lives. Sir Martin Landray was recently knighted for this work and RECOVERY’s legacy lives on, not just for Covid. Martin plans to revolutionise drug trials for other diseases too.

In the third and final part of our series How Covid Changed Science, Devi Sridhar Professor of Global Health at Edinburgh University looks at the legacy and lessons of the pandemic for scientific research. Tackling the virus became a global issue, but many have pointed out the inequality of both resources and effort in the response. Going forward do we need to be directing research more towards improving health and disease surveillance in less wealthy parts of the world, would investing there help prevent future pandemics?

In the second of our series How Covid Changed Science, Devi Sridhar, Professor of Global Health at Edinburgh University looks at the scientific messaging. Just how do you explain to both politicians and the public that a growing global pandemic is likely to kill many people, and unprecedented measures such as a nationwide lockdown are needed to prevent even more deaths. What information should be imparted and how? Similarly how to address the clamour for information on the development of vaccines and other potential treatments when there often wasn’t clarity? And with the rise of misinformation how did individual scientists who became the subject of conspiracy theories cope with being targeted? In this programme we hear from scientists and politicians directly involved with the pandemic response. For some the experience of explaining their often highly technical research to the general public was a daunting experience. For others it became a mission to answer the publics concerns and fears.

Until 2020 developing a new drug took at least 15 years. Scientists by and large competed with each other, were somewhat secretive about their research and only shared their data once publication was secured. And the public and the press had no interest in the various early phases of clinical trials. An incremental scientific step possibly on the road to somewhere was simply not newsworthy. Face masks were the preserves of hypochondriacs in the Far East, with no scientific evidence base for their use. Now the findings of research are published as soon as they are ready. Often they are being openly discussed in social media before they have been peer reviewed. The speed of research, collaboration between science and industry, and public perception of science are areas that have undergone incredible and likely permanent change. Devi Sridhar, Professor of Global Health at Edinburgh University hears from scientists in a variety of fields, whose working lives and practices have been affected, in some cases revolutionised by the pandemic.

If you look up into the night sky, there are around 7,000 active satellites orbiting the Earth. They’re part of our daily life – essential for things like the internet, the GPS in our cars and giving us weather reports. Seven thousand might not sound a lot in the infinite expanses of space. But the reality is that most satellites are found in a small slice of the solar system - called Lower Earth Orbit - and countries and satellite companies are planning to launch hundreds of thousands more in the next decade. So things are about to get crowded. In this week’s Discovery, Jane Chambers speaks to scientists, astronomers from the ALMA Observatory in Chile, space environmentalists and satellite companies like SpaceX about the benefits of this explosion in mega satellite constellations, as well as the unintended consequences to those who value a clear and unhindered view of the stars. Picture: Radio Telescopes at ALMA Observatory in the north of Chile, Credit: Jane Chambers

Giles Yeo learns how to make a Thai green curry with Meera Sodha. This is a recipe without meat or prawns but with tofu and lots of vegetables. If we need to eat less meat and dairy to help prevent global warming- what difference will altering our diets make to our health. For a long time now people have been urged to cut down on red meat and processed foods but if you have been eating them all your life it takes an effort to develop new habits. Plant based products that can replace for example dairy milks, cheeses, sausages, burgers and meat based dishes such as lasagne can be helpful in making this transition but are they healthier?

In Plant Based Promises, Giles Yeo a foodie and academic at Cambridge University, asks how sustainable are commercial plant based products? This is a fast growing sector with a potential value of $162 billion by 2030. Giles travels to the Netherlands Food Valley to look at companies developing plant based alternatives and to find out what role they have to play in changing diets. And Giles designs his own plant based Yeo Deli range online but discovers that new markets are already causing shortages of alternative proteins, so what will the future look like? In 2019 the Eat Lancet Commission set up specific targets for a healthy diet and sustainable food production. The aim was to keep global warming to within 1.5 degrees and to be able to feed the world’s 10 billion people by 2050. The Commission’s recommendations are best visualised as a plate of food, half fruits, vegetables and nuts and the other half whole grains, beans, legumes and pulses, plant oils and modest amounts of meat and dairy. Is there room on the plate for Giles Yeo Deli Baloney range.

In Plant Based Promises, foodie, researcher and broadcaster Giles Yeo looks at the science behind plant based diets and the increasing number of plant based products appearing in supermarkets and restaurants. The market for plant based products could be worth $162 billion in the next ten years and Giles asks how sustainable and healthy the products are and the role they play in decreasing the world's carbon footprint. Globally food production accounts for about 30% of greenhouse gases. In the UK we eat over six times the amount of meat and more than twice the amount of dairy products recommended to prevent the global temperature increasing more than 1.5 degrees C, after which extreme weather events become more severe. But eating less meat and dairy means new protein sources from plants are needed and how easy or practical is it for people to change their diets? Veganuary, where people pledge to go vegan for the month of January show that people are willing to change what they eat for a variety of reasons including animal welfare, sustainability and health. In programme one Giles, an expert on food intake looks at some of the foods being developed to replace animal based foods and looks at alternatives to the iconic cheeseburger. Giles meets biochemist Professor Pat Brown founder of Impossible Burgers, a Silicon Valley start up making burgers from genetically modified yeast to replicate the taste of meat. But from high tech to the artisanal, sisters Rachel and Charlotte Stevens missed eating cheese so much they are now making cheese alternatives using traditional moulds, cultures and aging techniques while replacing dairy ingredients with nuts.

The smaller the thing you look at, the bigger the microscope you need to use. That’s why the circular Large Hadron Collider at CERN, where they discovered the Higgs boson is 27 kilometres long, and its detectors tens of metres across. But to dig deeper still into the secrets of the Universe, they’re already talking about another machine 4 times bigger, to be built by the middle of the century. Roland Pease asks if it’s worth it. Image: CMS Beampipe removal LS2 2019 (Credit: Maximilien Brice/CERN)