Frankly Speaking About Family Medicine

Credits: 0.25 AMA PRA Category 1 Credit™   CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-480 Overview: Tune in as we discuss nonsurgical options for managing knee osteoarthritis in primary care. This episode reviews current guidelines and highlights new research on yoga as an effective alternative to traditional strengthening exercises. Gain practical insights to help patients reduce pain, improve function, and delay surgery—all while expanding your integrative treatment toolkit. Episode resource links: Abafita BJ, Singh A, Aitken D, et al. Yoga or strengthening exercise for knee osteoarthritis: a randomized clinical trial. JAMA Netw Open. 2025;8(4):e253698. doi:10.1001/jamanetworkopen.2025.3698 Brophy, Robert H. MD; Fillingham, Yale A. MD. AAOS Clinical Practice Guideline Summary: Management of Osteoarthritis of the Knee (Nonarthroplasty), Third Edition. Journal of the American Academy of Orthopaedic Surgeons 30(9):p e721-e729, May 1, 2022. | DOI: 10.5435/JAAOS-D-21-01233 Guest: Jillian Joseph, MPAS, PA-C Music Credit: Matthew Bugos Thoughts? Suggestions? Email us at [email protected]  The views expressed in this podcast are those of Dr. Domino and his guests and do not necessarily reflect the views of Pri-Med.

Credits: 0.25 AMA PRA Category 1 Credit™   CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-479 Overview: Listen in as we discuss how candesartan, an angiotensin receptor blocker (ARB), may offer a well-tolerated, cost-effective option for migraine attack prevention—even in normotensive patients. Learn to assess benefits, monitor for hypotension, and expand your preventive migraine toolkit with evidence-based insights that may improve adherence and access for patients struggling with traditional therapies. Episode resource links: The Lancet. Neurology. 2025;24(10):817-827. doi:10.1016/S1474-4422(25)00269-8. Cephalalgia : An International Journal of Headache. 2023;43(6):3331024231183166. doi:10.1177/03331024231183166. Guest: Robert A. Baldor MD, FAAFP   Music Credit: Matthew Bugos Thoughts? Suggestions? Email us at [email protected]  The views expressed in this podcast are those of Dr. Domino and his guests and do not necessarily reflect the views of Pri-Med.

Credits: 0.25 AMA PRA Category 1 Credit™   CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-478 Overview: As glucagon-like peptide-1 receptor agonists (GLP-1 RAs) become increasingly common in managing obesity, it is important for clinicians to recognize lesser-known adverse effects. This episode highlights the potential link between GLP-1 RAs and alopecia, equipping you to better evaluate, counsel, and manage patients reporting hair loss. Episode resource links: Alsuwailem OA, Alanazi R, Almutairi HM, Asiree RH, Almutairi W, Almutairi TM, Zamandar A, Alkhames S. Hair Loss Associated With Glucagon-Like Peptide-1 (GLP-1) Receptor Agonist Use: A Systematic Review. Cureus. 2025 Sep 16;17(9):e92454.  Guest: Alan M. Ehrlich, MD, FAAFP   Music Credit: Matthew Bugos Thoughts? Suggestions? Email us at [email protected]  The views expressed in this podcast are those of Dr. Domino and his guests and do not necessarily reflect the views of Pri-Med.

Credits: 0.25 AMA PRA Category 1 Credit™   CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-477 Overview: With rising administrative demands, many clinicians are considering artificial intelligence (AI) scribes—this episode unpacks what you need to know before incorporating this technology. We explore key benefits like reduced burnout and improved workflow, along with ethical, legal, and safety considerations to help you make informed decisions about integrating AI scribing into your practice. Episode resource links: Cohen IG, Ritzman J, Cahill RF. Ambient Listening—Legal and Ethical Issues. JAMA Netw Open.2025;8(2):e2460642. doi:10.1001/jamanetworkopen.2024.60642 Olson KD, Meeker D, Troup M, et al. Use of Ambient AI Scribes to Reduce Administrative Burden and Professional Burnout. JAMA Netw Open. 2025;8(10):e2534976. doi:10.1001/jamanetworkopen.2025.34976 https://www.healio.com/news/dermatology/20251210/ai-scribes-hold-transformative-potential-for-improving-physician-burden-patient-care Guest: Jillian Joseph, MPAS, PA-C   Music Credit: Matthew Bugos Thoughts? Suggestions? Email us at [email protected]  The views expressed in this podcast are those of Dr. Domino and his guests and do not necessarily reflect the views of Pri-Med.

Credits: 0.25 AMA PRA Category 1 Credit™   CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-476 Overview: Melatonin is widely used and often perceived as a safe, natural solution for insomnia. However, a new preliminary study raises concerns about long-term melatonin use and increased risk of heart failure, hospitalization, and all-cause mortality in patients with chronic insomnia. In this episode, we review the findings, discuss how they fit with existing evidence, explore limitations, and offer practical guidance for clinicians counseling patients about sleep supplements. Episode resource links: American Heart Association Scientific Sessions 2025 – Abstract 4371606 AHA Scientific Statement: Multidimensional Sleep Health and Cardiometabolic Risk (Circulation, 2025) Li et al. Lancet Diabetes & Endocrinology, 2024 American Academy of Sleep Medicine Clinical Practice Guidelines AHA Life’s Essential 8 & Sleep Health Resources Guest: Mariyan Montaque, DNP, FNP-BC   Music Credit: Matthew Bugos Thoughts? Suggestions? Email us at [email protected]  The views expressed in this podcast are those of Dr. Domino and his guests and do not necessarily reflect the views of Pri-Med.

Credits: 0.25 AMA PRA Category 1 Credit™   CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-475 Overview: A prescribing cascade occurs when adverse effects of a medication are mistaken for a new condition and treated with additional drugs. Older adults experiencing polypharmacy are most at risk. The impact of prescribing cascades can be substantial, leading to falls, organ injury, unnecessary imaging and tests, and more. Join us as we explore how to recognize and prevent these harmful cascades in your patients. Episode resource links: Adrien  O, Mohammad  AK, Hugtenburg  JG,  et al.  Prescribing cascades with recommendations to prevent or reverse them: a systematic review.   Drugs Aging. 2023;40(12):1085-1100. doi:10.1007/s40266-023-01072-yPubMedGoogle ScholarCrossref   Brath  H, Mehta  N, Savage  RD,  et al.  What is known about preventing, detecting, and reversing prescribing cascades: a scoping review.   J Am Geriatr Soc. 2018;66(11):2079-2085. doi:10.1111/jgs.15543PubMedGoogle ScholarCrossref   Daunt R, McGettigan S, Kelly L, Curtin D, O'Mahony D. Detection of Potential Prescribing Cascades in Multimorbid Older Patients Hospitalised with Acute Illness-An Observational Prospective Prevalence Study. Drugs Aging. 2025;42(6):535-546. doi:10.1007/s40266-025-01201-9   Growdon ME, Tjota N, Campbell R, et al. Decision-Making and Downstream Outcomes of the Gabapentinoid-Diuretic Prescribing Cascade. JAMA Netw Open. 2025;8(12):e2545274. doi:10.1001/jamanetworkopen.2025.45274   McCarthy  LM, Savage  R, Dalton  K,  et al.  ThinkCascades: a tool for identifying clinically important prescribing cascades affecting older people.   Drugs Aging. 2022;39(10):829-840. doi:10.1007/s40266-022-00964-9PubMedGoogle ScholarCrossref   O’Mahony, D., Cherubini, A., Guiteras, A.R. et al. STOPP/START criteria for potentially inappropriate prescribing in older people: version 3. Eur Geriatr Med 14, 625–632 (2023). https://doi.org/10.1007/s41999-023-00777-y   Rochon, P.A., O’Mahony, D., Cherubini, A. et al. International expert panel’s potentially inappropriate prescribing cascades (PIPC) list. Eur Geriatr Med 16, 1573–1584 (2025). https://doi.org/10.1007/s41999-025-01215-x   Young EH, Pan S, Yap AG, Reveles KR, Bhakta K. Polypharmacy prevalence in older adults seen in United States physician offices from 2009 to 2016. PLoS One. 2021;16(8):e0255642. Published 2021 Aug 3. doi:10.1371/journal.pone.0255642 Guest: Susan Feeney, DNP, FNP-BC, NP-C   Music Credit: Matthew Bugos Thoughts? Suggestions? Email us at [email protected]  The views expressed in this podcast are those of Dr. Domino and his guests and do not necessarily reflect the views of Pri-Med.

Credits: 0.25 AMA PRA Category 1 Credit™   CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-474 Overview: Depression affects many people with dementia, but some evidence suggests certain antidepressants may accelerate cognitive decline. This episode explores the potential risks of antidepressants in people with dementia, which medications require careful consideration, and how to make informed prescribing decisions that optimize patient outcomes while minimizing potential cognitive harm. Episode resource links: Mo M, Abzhandadze T, Hoang MT, et al. Antidepressant use and cognitive decline in patients with dementia: a national cohort study. BMC Med. 2025;23(1):82.  Guest: Alan M. Ehrlich, MD, FAAFP Music Credit: Matthew Bugos Thoughts? Suggestions? Email us at [email protected]  The views expressed in this podcast are those of Dr. Domino and his guests and do not necessarily reflect the views of Pri-Med.

Credits: 0.25 AMA PRA Category 1 Credit™   CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-473 Overview: Join us as we review long-term outcomes from a recently published trial on prostate-specific antigen (PSA) testing and prostate cancer mortality. Learn how updated evidence informs shared decision-making and balances early detection with potential harms. Equip yourself to guide patients through nuanced discussions on PSA testing’s limitations, mortality data, and meaningful clinical impact. Episode resource links: N Engl J Med 2025;393:1669-80. DOI: 10.1056/NEJMoa2503223 Recommendation: Prostate Cancer: Screening | United States Preventive Services Taskforce Guest: Robert A. Baldor MD, FAAFP Music Credit: Matthew Bugos Thoughts? Suggestions? Email us at [email protected]  The views expressed in this podcast are those of Dr. Domino and his guests and do not necessarily reflect the views of Pri-Med.

Credits: 0.25 AMA PRA Category 1 Credit™   CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-472 Overview: The transition from hospital to home is a valuable period for patients and clinicians. In this episode, we discuss which patients require follow-up, what should be reviewed during these appointments, and when follow-up should take place to help improve patient outcomes. Episode resource links: Anderson, T. S., Herzig, S. J., Marcantonio, E. R., Yeh, R. W., Souza, J., & Landon, B. E. (2024, April). Medicare transitional care management program and changes in timely postdischarge follow-up. In JAMA Health Forum (Vol. 5, No. 4, pp. e240417-e240417). American Medical Association. Anderson, T. S., Wilson, L. M., Wang, B. X., Steinman, M. A., Schonberg, M. A., Marcantonio, E. R., & Herzig, S. J. (2025). Medication Errors and Gaps in Medication Discharge Planning for Hospitalized Older Adults: A Prospective Cohort Study. Journal of general internal medicine, 1-10.   Balasubramanian, I., Andres, E. B., & Malhotra, C. (2025). Outpatient follow-up and 30-day readmissions: a systematic review and meta-analysis. JAMA Network Open, 8(11), e2541272-e2541272. Guest: Mariyan L. Montaque, DNP, FNP-BC Music Credit: Matthew Bugos Thoughts? Suggestions? Email us at [email protected]  The views expressed in this podcast are those of Dr. Domino and his guests and do not necessarily reflect the views of Pri-Med.

Credits: 0.25 AMA PRA Category 1 Credit™   CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-471 Overview: Discover how flexible physical activity patterns can reduce mortality and cardiovascular risk in patients with diabetes. This episode translates evidence on “weekend warrior” vs regular exercise into practical counseling strategies, empowering you to help time-constrained patients achieve the mortality benefits of weekly moderate-to-vigorous physical activity—regardless of scheduling pattern. Episode resource links: Wu, Z., Sheng, C., Guo, Z., Zheng, Y., Zheng, D., Li, X., Guo, X., & Li, H. (2025). Association of Weekend Warrior and Other Physical Activity Patterns With Mortality Among Adults With Diabetes : A Cohort Study. Annals of internal medicine, 178(9), 1279–1286. https://doi.org/10.7326/ANNALS-25-00640 Guest: Jill M. Terrien PhD, ANP-BC  Music Credit: Matthew Bugos Thoughts? Suggestions? Email us at [email protected]  The views expressed in this podcast are those of Dr. Domino and his guests and do not necessarily reflect the views of Pri-Med.

Credits: 0.25 AMA PRA Category 1 Credit™   CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-470 Overview: Social media use is nearly ubiquitous among adolescents, raising concern about its role in rising rates of depression, anxiety, insomnia, and suicidality. Although prior evidence has been mixed, emerging studies offer new insights on the relationship between social media use and adolescent mental health. Join us as we review current literature and discuss potential strategies to mitigate negative impacts and improve outcomes. Episode resource links: Calvert E, Cipriani M, Dwyer B, et al. Social Media Detox and Youth Mental Health. JAMA Netw Open. 2025;8(11):e2545245. doi:10.1001/jamanetworkopen.2025.45245 https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2840489   Clayborne ZM, Capaldi CA, Mehra VM. Associations between digital media use behaviours, screen time and positive mental health in youth: results from the 2019 Canadian Health Survey on Children and Youth. BMC Public Health. 2025;25(1):2303. Published 2025 Jul 3. doi:10.1186/s12889-025-22874-2 Grøntved A, Singhammer J, Froberg K, et al. A prospective study of screen time in adolescence and depression symptoms in young adulthood. Prev Med. 2015;81:108-113. doi:10.1016/j.ypmed.2015.08.009 Nagata JM, Memon Z, Talebloo J, et al. Prevalence and Patterns of Social Media Use in Early Adolescents. Acad Pediatr. 2025;25(4):102784. doi:10.1016/j.acap.2025.102784 Oberle E, Ji XR, Kerai S, Guhn M, Schonert-Reichl KA, Gadermann AM. Screen time and extracurricular activities as risk and protective factors for mental health in adolescence: A population-level study. Prev Med. 2020;141:106291. doi:10.1016/j.ypmed.2020.106291 Pieh C, Humer E, Hoenigl A, et al. Smartphone screen time reduction improves mental health: a randomized controlled trial. BMC Med. 2025;23(1):107. Published 2025 Feb 21. doi:10.1186/s12916-025-03944-z Riehm KE, Feder KA, Tormohlen KN, et al. Associations Between Time Spent Using Social Media and Internalizing and Externalizing Problems Among US Youth. JAMA Psychiatry. 2019;76(12):1266–1273. doi:10.1001/jamapsychiatry.2019.2325 Varona MN, Muela A, Machimbarrena JM. Problematic use or addiction? A scoping review on conceptual and operational definitions of negative social networking sites use in adolescents. Addict Behav. 2022;134:107400. doi:10.1016/j.addbeh.2022.107400 Woolf SH. The Youth Mental Health Crisis in the United States: Epidemiology, Contributors, and Potential Solutions. Pediatrics. 2025;156(5):e2025070849. doi:10.1542/peds.2025-070849 Xiang AH, Martinez MP, Chow T, et al. Depression and Anxiety Among US Children and Young Adults. JAMA Netw Open. 2024;7(10):e2436906. doi:10.1001/jamanetworkopen.2024.36906 BBC: Australia has banned social media for kids under 16. How will it work? https://www.bbc.com/news/articles/cwyp9d3ddqyo Guest: Susan Feeney, DNP, FNP-BC, NP-C   Music Credit: Matthew Bugos Thoughts? Suggestions? Email us at [email protected]  The views expressed in this podcast are those of Dr. Domino and his guests and do not necessarily reflect the views of Pri-Med.

Credits: 0.25 AMA PRA Category 1 Credit™   CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-469 Overview: Tune in to hear how self-collected vaginal human papillomavirus (HPV) testing has potential to expand access to cervical cancer screening and reduce barriers for your patients. This episode reviews cervical cancer screening guidelines, follow-up recommendations, and how to consider offering self-collection as an option to increase screening rates and improve preventive care in your practice. Episode resource links: CA CancerJClin.2026;e70041. DOI:10.3322/caac.70041 US Food and Drug Administration (FDA). Device Classification Under Section 513(f)(2)(De Novo). Device for home collection and transport of vaginal specimens by lay users for use in an approved HPV molecular assay. FDA; 2025. [email protected]  The views expressed in this podcast are those of Dr. Domino and his guests and do not necessarily reflect the views of Pri-Med.

Credits: 0.25 AMA PRA Category 1 Credit™   CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-nutrition-update Overview: In this episode, we explore the latest changes to the USDA’s nutrition guidelines, trace the history of the food pyramid, and examine the evidence behind current guidance. Come away with tips to counsel patients on nutrition that supports long-term health and reduces chronic disease risk. Episode resource links: Review the history of nutrition recommendations from the United States Department of Agriculture (USDA) Analyze the USDA’s 2026 food guidelines Guest: Alan M. Ehrlich, MD, FAAFP   Music Credit: Matthew Bugos Thoughts? Suggestions? Email us at [email protected]  The views expressed in this podcast are those of Dr. Domino and his guests and do not necessarily reflect the views of Pri-Med.

Credits: 0.25 AMA PRA Category 1 Credit™   CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-468 Overview: We first discussed aspirin use for primary prevention of cardiovascular disease in 2022 when the USPSTF recommended against it. In this follow-up episode, we review new trial data reinforcing that guidance and help you translate the evidence into safer prevention strategies. Build confidence in supporting patients with evidence-based approaches to reduce cardiovascular risk. Episode resource links: Aspirin, cardiovascular events, and major bleeding in older adults: extended follow-up of the ASPREE trial. Eur Heart J. 2025 Aug 12:ehaf514. doi: 10.1093/eurheartj/ehaf514. Epub ahead of print. PMID: 40796244. Guest: Robert A. Baldor MD, FAAFP   Music Credit: Matthew Bugos Thoughts? Suggestions? Email us at [email protected] The views expressed in this podcast are those of Dr. Domino and his guests and do not necessarily reflect the views of Pri-Med.

Credits: 0.25 AMA PRA Category 1 Credit™   CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-vaccine-update Overview: In this episode, we discuss the recently updated US childhood vaccine schedule, including key changes and the rationale behind these recommendations. We also talk about the risks of vaccine-preventable illnesses and review vaccine efficacy and safety considerations—helping you navigate evolving guidance and protect patients in primary care. Episode resource links: RSV:  Pediatrics. 2024. Curns AT, Rha B, Lively JY, et al. J Infect Dis. 2022 Aug 15;226(Suppl 2):S154-S163. doi: 10.1093/infdis/jiac120 Hep B: N Engl J Med 2019;380:2041-2050  DOI: 10.1056/NEJMra181047 Clin Infect Dis. 2021 Nov 2;73(9):e3317-e3323. doi: 10.1093/cid/ciaa898.  Meningococcal Vaccines and disease: MMWR. Morbidity and Mortality Weekly Report. 2024. Collins JP, Crowe SJ, Ortega-Sanchez IR, et al. Vaccine. 2019. Wang B, Santoreneos R, Giles L, Haji Ali Afzali H, Marshall H. Guest: Jillian Joseph, MPAS, PA-C Music Credit: Matthew Bugos Thoughts? Suggestions? Email us at [email protected] The views expressed in this podcast are those of Dr. Domino and his guests and do not necessarily reflect the views of Pri-Med.  

Credits: 0.25 AMA PRA Category 1 Credit™   CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-467 Overview: Join us as we discuss recent changes to newborn hepatitis B vaccination recommendations and review the risks, benefits, and rationale for immunizing this patient population. Come away with confidence to navigate new guidance, thoughtfully address parental concerns, and provide evidence-based care that promotes both infant and public health. Episode resource links: N Engl J Med 2019;380:2041-2050  DOI: 10.1056/NEJMra181047 Clin Infect Dis. 2021 Nov 2;73(9):e3317-e3323. doi: 10.1093/cid/ciaa898.  Guest: Robert A. Baldor MD, FAAFP   Music Credit: Matthew Bugos Thoughts? Suggestions? Email us at [email protected]  

Credits: 0.25 AMA PRA Category 1 Credit™   CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-466 Overview: Concerns over eating carbohydrate-rich potatoes have been raised over the last decade with numerous studies suggesting worrisome effects on health. Tune in as we unpack findings from a large study that examined the relationship between potato intake and the risk of developing type 2 diabetes mellitus (T2DM), helping you apply evolving nutrition science to patient counseling. Episode resource links: BMJ 2025;390:e082121 http://dx.doi.org/10.1136/bmj-2024‑082121 Guest: Robert A. Baldor MD, FAAFP   Music Credit: Matthew Bugos Thoughts? Suggestions? Email us at [email protected]  

Credits: 0.25 AMA PRA Category 1 Credit™   CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-465 Overview: Many patients with coronary artery disease take aspirin, but how should clinicians navigate management when an anticoagulant is also needed? In this episode, we review indications for therapy, explore evidence on dual use, and discuss how to counsel patients on balancing cardiovascular benefits with the risks of combination therapy. Episode resource links: Lemesle G, Didier R, Steg PG, et al. Aspirin in Patients with Chronic Coronary Syndrome Receiving Oral Anticoagulation. N Engl J Med. Published online August 31, 2025. https://www.nejm.org/doi/full/10.1056/NEJMoa2507532 Guest: Alan M. Ehrlich, MD, FAAFP   Music Credit: Matthew Bugos Thoughts? Suggestions? Email us at [email protected]  

Credits: 0.25 AMA PRA Category 1 Credit™   CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-464 Overview: Beyond detecting disease early, lung cancer screening provides an opportunity to encourage smoking cessation. In this episode, we review USPSTF guidelines, compare screening effectiveness, and explore how the use of a pulmonary function test (PFT) and a lung age estimator can help people who smoke better understand their risks and inspire behavior change. Episode resource links: USPSTF: https://www.uspreventiveservicestaskforce.org/uspstf/recommendation/lung-cancer-screening BMJ (Clinical Research Ed.). 2008;336(7644):598-600. doi:10.1136/bmj.39503.582396.25. BMC Public Health. 2022;22(1):1164. doi:10.1186/s12889-022-13583-1. Guest: Robert A. Baldor MD, FAAFP Music Credit: Matthew Bugos Thoughts? Suggestions? Email us at [email protected]  

Credits: 0.25 AMA PRA Category 1 Credit™   CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-463 Overview: Listen in as we discuss how integrating behavioral therapies into the management of chronic back pain can improve function, reduce opioid use, and empower patients. Boost your clinical toolkit with evidence-based strategies that enhance outcomes while aligning with evolving guidelines for safer, multimodal approaches to chronic pain care. Episode resource links: Zgierska AE, Edwards RR, Barrett B, et al. Mindfulness vs Cognitive Behavioral Therapy for Chronic Low Back Pain Treated With Opioids: A Randomized Clinical Trial. JAMA Netw Open. 2025;8(4):e253204. doi:10.1001/jamanetworkopen.2025.3204 Dowell D, Ragan KR, Jones CM, Baldwin GT, Chou R. CDC Clinical Practice Guideline for Prescribing Opioids for Pain - United States, 2022. MMWR Recomm Rep. 2022 Nov 4;71(3):1-95. doi: 10.15585/mmwr.rr7103a1. PMID: 36327391; PMCID: PMC9639433. Guest: Jillian Joseph, MPAS, PA-C Music Credit: Matthew Bugos Thoughts? Suggestions? Email us at [email protected]  

Credits: 0.25 AMA PRA Category 1 Credit™   CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-462 Overview: In this episode, we examine migraine—a leading cause of disability worldwide that is often underdiagnosed and undertreated in primary care. You’ll learn how to distinguish migraine from other headache disorders, identify who is most affected, and explore both acute pharmacologic options and preventive strategies that can reduce attack frequency and improve patients’ quality of life. Episode resource links: El Hussein, M. T., & Fraser, L. (2025). Pharmacologic Management of Migraine in Primary Care: Nurse Practitioner Guide. The Journal for Nurse Practitioners, 21(9), 105501. Qaseem, A., Tice, J. A., Etxeandia-Ikobaltzeta, I., Wilt, T. J., Harrod, C. S., Cooney, T. G., ... & Yost, J. (2025). Pharmacologic treatments of acute episodic migraine headache in outpatient settings: a clinical guideline from the American College of Physicians. Annals of internal medicine, 178(4), 571-578. Charles, A. C., Tepper, S. J., & Ailani, J. (2025). State of the art in the management of migraine—A response to the American College of Physicians migraine preventive treatment guideline. Headache: The Journal of Head and Face Pain. Vélez-Jiménez MK, et al. Comprehensive Preventive Treatments for Episodic Migraine: Systematic Review. Front Neurol. 2025 Lanteri-Minet, M., Casarotto, C., Bretin, O., Collin, C., Gugenheim, M., Raclot, V., ... & Lefebvre, H. (2025). Prevalence, characteristics and management of migraine patients with triptan failure in primary care: the EMR France-Mig study. The Journal of Headache and Pain, 26(1), 153. Guest: Mariyan L. Montaque, DNP, FNP-BC   Music Credit: Matthew Bugos Thoughts? Suggestions? Email us at [email protected]  

Credits: 0.25 AMA PRA Category 1 Credit™   CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-461 Overview: Complicated urinary tract infections (UTIs) are common in primary care but can be difficult to approach. In this episode, you’ll learn how to identify complicated UTIs, methodically address them, and incorporate new guidance on outpatient management and antibiotic selection to improve diagnosis and treatment for your patients. Episode resource links: Complicated Urinary Tract Infections (cUTI): Clinical Guidelines for Treatment and Management https://www.idsociety.org/practice-guideline/complicated-urinary-tract-infections Koehl J, Spolsdoff D, Negaard B, et al. Cephalosporins for Outpatient Pyelonephritis in the Emergency Department: COPY-ED Study. Ann Emerg Med. 2025;85(3):240-248. https://pubmed.ncbi.nlm.nih.gov/39570254/ Guest: Alan M. Ehrlich, MD, FAAFP   Music Credit: Matthew Bugos Thoughts? Suggestions? Email us at [email protected]  

Credits: 0.25 AMA PRA Category 1 Credit™   CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-460 Overview: Join us as we discuss how frequently patients with stable hypertension should monitor their blood pressure at home. Hear insights from two trials to help you provide evidence-based, cost-conscious guidance—reducing unnecessary alarms while supporting better long-term management. Episode resource links: Rose, Francesa; Stevens, Richard S.a; Morton, Kate S.b; Yardley, Lucyc; McManus, Richard J.a,d. How often should self-monitoring of blood pressure be repeated? A secondary analysis of data from two randomized controlled trials. Journal of Hypertension ():10.1097/HJH.0000000000004123, August 20, 2025. | DOI: 10.1097/HJH.0000000000004123 Guest: Robert A. Baldor MD, FAAFP   Music Credit: Matthew Bugos Thoughts? Suggestions? Email us at [email protected]  

Credits: 0.25 AMA PRA Category 1 Credit™   CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-459 Overview: Cognitive decline risk may be reduced through modifiable lifestyle factors, creating an opportunity for early intervention in primary care. Join us as we review findings from the US POINTER trial, which evaluated the impact of structured vs. self-guided lifestyle interventions on the risk of cognitive decline in older adults. Come away with tips to apply this evidence in real-world scenarios with your patients. Episode resource links: Baker LD, Espeland MA, Whitmer RA, et al. Structured vs self-guided multidomain lifestyle interventions for global cognitive function: The US POINTER randomized clinical trial. JAMA. 2025;334(8):681-691. doi:10.1001/jama.2025.12923 Livingston G, Huntley J, Liu KY, et al. Dementia prevention, intervention, and care: 2024 report of the Lancet standing Commission. Lancet. 2024;404(10421):572-628. doi:10.1016/S0140-6736(24)01296-0 Guest: Jillian Joseph, MPAS, PA-C Music Credit: Matthew Bugos Thoughts? Suggestions? Email us at [email protected]   

Credits: 0.25 AMA PRA Category 1 Credit™   CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-458 Overview: In this episode, we explore the relationship between caffeine consumption and suicide risk. Hear how coffee may offer protective effects—while energy drinks raise concern—and gain practical tips for screening patients for caffeine and substance use as part of suicide risk assessment in primary care. Episode resource links: Low, C.E.; Chew, N.S.M.; Loke, S.; Tan, J.Y.; Phee, S.; Lee, A.R.Y.B.; Ho, C.S.H. Association of Coffee and Energy Drink Intake with Suicide Attempts and Suicide Ideation: A Systematic Review and Meta-Analysis. Nutrients 2025, 17, 1911. https://doi.org/10.3390/ nu17111911   Costantino, A., Maiese, A., Lazzari, J., Casula, C., Turillazzi, E., Frati, P., & Fineschi, V. (2023). The Dark Side of Energy Drinks: A Comprehensive Review of Their Impact on the Human Body. Nutrients, 15(18), 3922. https://doi.org/10.3390/nu15183922 Guest: Jill M. Terrien PhD, ANP-BC    Music Credit: Matthew Bugos Thoughts? Suggestions? Email us at [email protected]  

Credits: 0.25 AMA PRA Category 1 Credit™   CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-457 Overview: Many patients turn to low- and no-calorie sweeteners to help with weight loss and lower diabetes risk, but do these alternatives actually deliver? In this episode, we review common artificial sweeteners and explore evidence on hunger, cardiovascular, diabetes, and dementia risks to understand how sugar substitutes can impact long-term health outcomes in your patients. Episode resource links: fMRI Data: Nat Metab 7, 574–585 (2025). https://doi.org/10.1038/s42255-025-01227-8 Adverse effects: Adv Nutr. 2023 Jul;14(4):710-717. doi: 10.1016/j.advnut.2023.05.010 Dementia Data: Neurology® 2025;105:e214023. doi:10.1212/WNL.0000000000214023 Stevia: Obes Rev. 2025 Jun;26(6):e13902. doi: 10.1111/obr.13902 High Fructose Corn Syrup:  Nutrition Reviews. 2021;79(2):209-226.  doi:10.1093/nutrit/nuaa077 Guest: Robert A. Baldor MD, FAAFP Music Credit: Matthew Bugos Thoughts? Suggestions? Email us at [email protected]   

Credits: 0.25 AMA PRA Category 1 Credit™   CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-456 Overview: Experiences of significant pain and anxiety during intrauterine device (IUD) insertion may lead patients to forgo this effective contraceptive option. Listen in as we discuss how to reduce procedural pain, address anxiety, and foster trust using updated guidelines and shared decision-making to improve patient satisfaction and support informed contraceptive choices. Episode resource links: Charles, D. N., Nagarsheth, M., & Oshman, L. (2025). Pain Management for IUD Insertion in Primary Care. American Family Physician, 111(4), 299-301. Dempsey, A., Aucoin, C., Stallings, W., Kulangara, A., & Sundstrom, B. (2025). Beyond pain medication: striving toward more patient-centered placement of intrauterine devices. Contraception, 110944. Estevez, E., Hem-Lee-Forsyth, S., Viechweg, N. D., John, S., & Menor, S. P. (2024). Advancing pain management protocols for intrauterine device insertion: integrating evidence-based strategies into clinical practice. Cureus, 16(6). Hoover, K., & Riley, K. (2025). Pain Management for In-Office Uterine and Cervical Procedures. Guest: Mariyan L. Montaque, DNP, FNP-BC   Music Credit: Matthew Bugos Thoughts? Suggestions? Email us at [email protected]  

Credits: 0.25 AMA PRA Category 1 Credit™   CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-455 Overview: Microscopic hematuria is common in primary care, but not every patient needs an urgent urology referral. Tune in to learn how to apply the latest evidence-based guidelines to risk-stratify patients and confidently manage workup and follow-up from your clinic, improving care while reducing unnecessary testing. Episode resource links: Barocas DA, Lotan Y, Matulewicz RS, Raman JD, Westerman ME, Kirkby E, Pak L, Souter L. Updates to Microhematuria: AUA/SUFU Guideline (2025). J Urol. 0(0). doi: 10.1097/JU.0000000000004490. Guest: Robert A. Baldor MD, FAAFP   Music Credit: Matthew Bugos Thoughts? Suggestions? Email us at [email protected]  

Credits: 0.25 AMA PRA Category 1 Credit™   CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-454 Overview: Treating hypertension within the first month can significantly improve long-term blood pressure control. This episode reviews new evidence and practical strategies to help you initiate timely therapy, optimize follow-up, and improve outcomes for patients with newly diagnosed, uncontrolled hypertension. Gain actionable insights to close a critical care gap. Episode resource links: Barrett, R. B., Riesser, B., Martin, B., Sachdev, N., Rakotz, M. K., Sutherland, S. E., & Egan, B. M. (2025). Treatment in the First Month After Hypertension Diagnosis Improves Blood Pressure Control. Hypertension (Dallas, Tex. : 1979), 82(6), 1129–1136. https://doi.org/10.1161/HYPERTENSIONAHA.124.23508 For your patients: 10 Ways to Control High Blood Pressure Without Medication  For your patients: Natural Ways to Lower Blood Pressure  Guest: Jill M. Terrien PhD, ANP-BC    Music Credit: Matthew Bugos Thoughts? Suggestions? Email us at [email protected]  

Credits: 0.25 AMA PRA Category 1 Credit™   CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-453 Overview: Many patients are still hesitant about the shingles vaccine, but the benefits go far beyond preventing a painful rash. Hear how varicella zoster vaccination can also reduce the risks of postherpetic neuralgia, dementia, and cardiovascular events, giving you powerful tools to guide more informed patient decisions. Episode resource links: Dementia: Neurol Sci. 2024 Jan;45(1):27-36.  doi: 10.1007/s10072-023-07038-7 CV: J Infect Dis. 2025 Feb 28:jiaf105. doi: 10.1093/infdis/jiaf105  Guest: Robert A. Baldor MD, FAAFP Music Credit: Matthew Bugos Thoughts? Suggestions? Email us at [email protected]  

Credits: 0.25 AMA PRA Category 1 Credit™   CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-452 Overview: The healthcare landscape is evolving rapidly, and clinicians are navigating conflicting guidance on established, evidence-based recommendations. Recent news suggest acetaminophen use during pregnancy causes autism spectrum disorder (ASD), which is not the consensus of medical experts based on available data. When guidance from various sources conflicts with established research, clinicians face challenges in providing evidence-based care. Join us to review the current evidence on acetaminophen and ASD risk.  Episode resource links: Ahlqvist VH, Sjöqvist H, Dalman C, et al. Acetaminophen Use During Pregnancy and Children’s Risk of Autism, ADHD, and Intellectual Disability. JAMA. 2024;331(14):1205–1214. doi:10.1001/jama.2024.3172   Damkier, P., Gram, E. B., Ceulemans, M., Panchaud, A., Cleary, B., Chambers, C., Weber-Schoendorfer, C., Kennedy, D., Hodson, K., Grant, K. S., Diav-Citrin, O., Običan, S. G., Shechtman, S., & Alwan, S. (2025). Acetaminophen in Pregnancy and Attention-Deficit and Hyperactivity Disorder and Autism Spectrum Disorder. Obstetrics and gynecology, 145(2), 168–176. https://doi.org/10.1097/AOG.0000000000005802   Ji Y, Azuine RE, Zhang Y, et al. Association of Cord Plasma Biomarkers of In Utero Acetaminophen Exposure With Risk of Attention-Deficit/Hyperactivity Disorder and Autism Spectrum Disorder in Childhood. JAMA Psychiatry. 2020;77(2):180–189. doi:10.1001/jamapsychiatry.2019.3259   Hirota T, King BH.  Autism Spectrum Disorder: A Review. JAMA. 2023;329(2):157–168. doi:10.1001/jama.2022.23661   Liu, X., Zou, M., Sun, C., Wu, L., & Chen, W. X. (2022). Prenatal Folic Acid Supplements and Offspring's Autism Spectrum Disorder: A Meta-analysis and Meta-regression. Journal of autism and developmental disorders, 52(2), 522–539. https://doi.org/10.1007/s10803-021-04951-8   DSM-5-TR: Neurocognitive Disorders Supplement; October 2022. https://psychiatryonline.org/pb-assets/dsm/update/DSM-5-TR_Neurocognitive-Disorders-Supplement_2022_APA_Publishing.pdf https://www.npr.org/sections/shots-health-news/2025/09/06/nx-s1-5532143/hhs-responds-to-report-about-autism-and-acetaminophen Guest: Susan Feeney, DNP, FNP-BC, NP-C   Music Credit: Matthew Bugos Thoughts? Suggestions? Email us at [email protected]   

Credits: 0.25 AMA PRA Category 1 Credit™   CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-451 Overview: The obesity epidemic has fueled a demand for weight loss medications. Trials have directly compared medications—specifically glucagon-like peptide-1 receptor agonists (GLP-1 RAs)—with a recent study doing just that. Tune in as we explore the evidence comparing semaglutide and tirzepatide for weight loss outcomes up to 1 year. Episode resource links: Rodriguez PJ, Goodwin Cartwright BM, Gratzl S, et al. Semaglutide vs Tirzepatide for Weight Loss in Adults With Overweight or Obesity. JAMA Intern Med. 2024;184(9):1056-1064.  Moiz A, Filion KB, Toutounchi H, et al. Efficacy and Safety of Glucagon-Like Peptide-1 Receptor Agonists for Weight Loss Among Adults Without Diabetes : A Systematic Review of Randomized Controlled Trials. Ann Intern Med. 2025;178(2):199-217.  Wen J, Syed B, Nadora D, et al. Tirzepatide Versus Semaglutide on Weight Loss in Type 2 Diabetes Patients: A Systematic Review and Meta-Analysis of Direct Comparative Studies. Endocrinol Diabetes Metab. 2025;8(3):e70045.  Guest: Alan M. Ehrlich, MD, FAAFP Music Credit: Matthew Bugos Thoughts? Suggestions? Email us at [email protected]  

Credits: 0.25 AMA PRA Category 1 Credit™   CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-450 Overview: Use of e-cigarettes has increased significantly over the last several years and their popularity continues to grow, notably among adolescents and young adults. Recent evidence indicates that the majority of teens and young adults who vape consider quitting; however, nicotine addiction has historically been difficult to treat in this population. Join us as we discuss the prevalence of vaping, associated harms, and new evidence on the effectiveness of varenicline on cessation.  Episode resource links: CDC https://www.cdc.gov/tobacco/e-cigarettes/youth.html Evins, A. E., Cather, C., Reeder, H. T., Evohr, B., Potter, K., Pachas, G. N., Gray, K. M., Levy, S., Rigotti, N. A., Iroegbulem, V., Dufour, J., Casottana, K., Costello, M. A., Gilman, J. M., & Schuster, R. M. (2025). Varenicline for Youth Nicotine Vaping Cessation: A Randomized Clinical Trial. JAMA, e253810. Advance online publication. https://doi.org/10.1001/jama.2025.3810 Lindson N, Butler AR, McRobbie H, et al. Electronic cigarettes for smoking cessation. Cochrane Database Syst Rev. 2024;1(1):CD010216. Published 2024 Jan 8. doi:10.1002/14651858.CD010216.pub8 Park-Lee E, Ren C, Sawdey MD, et al. Notes from the Field: E-Cigarette Use Among Middle and High School Students — National Youth Tobacco Survey, United States, 2021. MMWR Morb Mortal Wkly Rep 2021;70:1387–1389. DOI: http://dx.doi.org/10.15585/mmwr.mm7039a4external icon;  Tuisku A, Rahkola M, Nieminen P, Toljamo T. Electronic Cigarettes vs Varenicline for Smoking Cessation in Adults: A Randomized Clinical Trial. JAMA Intern Med. 2024;184(8):915–921. doi:10.1001/jamainternmed.2024.1822 Zhang, L., Gentzke, A., Trivers, K. F., & VanFrank, B. (2022). Tobacco Cessation Behaviors Among U.S. Middle and High School Students, 2020. The Journal of adolescent health : official publication of the Society for Adolescent Medicine, 70(1), 147–154. https://doi.org/10.1016/j.jadohealth.2021.07.011 Guest: Susan Feeney, DNP, FNP-BC, NP-C Music Credit: Matthew Bugos Thoughts? Suggestions? Email us at [email protected]  

Credits: 0.25 AMA PRA Category 1 Credit™   CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-449 Overview: In this episode, we discuss new evidence linking high compliance with the Dietary Approaches to Stop Hypertension (DASH) diet to lower risks of colorectal cancer, reinforcing the DASH diet’s well-established role in managing hypertension while also highlighting its potential to reduce cancer risk. Gain practical insights into translating these findings into actionable nutrition guidance to support your patients’ overall health. Episode resource links: Explain the risk factors for development of colorectal cancers Review the Dietary Approaches to Stop Hypertension (DASH) and discuss the proposed mechanisms for colorectal cancer reduction by following this approach Apply evidence from a meta-analysis to support dietary counseling strategies aimed at cancer prevention in clinical settings Guest: Jillian Joseph, MPAS, PA-C   Music Credit: Matthew Bugos Thoughts? Suggestions? Email us at [email protected]  

Credits: 0.25 AMA PRA Category 1 Credit™   CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-448 Overview: Join us to discover how flavan-3-ols, found in tea, cocoa, and select fruits, can support cardiovascular prevention. Learn how to translate emerging evidence on blood pressure and vascular health into practical dietary guidance that empowers your patients and complements standard hypertension care. Episode resource links: European Journal of Preventive Cardiology (2025) 00, 1–13. https://doi.org/10.1093/eurjpc/zwaf173 Guest: Robert A. Baldor MD, FAAFP   Music Credit: Matthew Bugos Thoughts? Suggestions? Email us at [email protected]  

Credits: 0.25 AMA PRA Category 1 Credit™   CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-447 Overview: New data show that quitting smoking—even at age 65 or 75—can still add years to life. In this episode, we review the latest evidence on life expectancy gains and equip you with effective, evidence-based tools to support tobacco cessation and motivate patients at any age. Episode resource links: Le,Thuy TT., Mendez, D. , & Warner, K. (2024). The Benefits of Quitting Smoking at Different Ages. American Journal of Preventive Medicine, 67 (5), 684-688. https://doi.org/10.1016/j.amepre.2024.06.020.    What are the treatments for tobacco dependence? National Institute on Drug Abuse https://nida.nih.gov/publications/research-reports/tobacco-nicotine-e-cigarettes/what-are-treatments-tobacco-dependence Smokefree.gov offers Apps, counseling, texting support, tools and tips for your patient to build your quit plan Selby, P., & Zawertailo, L. (2022). Tobacco Addiction. The New England journal of medicine, 387(4), 345–354. https://doi.org/10.1056/NEJMcp2032393 Guest: Jill M. Terrien PhD, ANP-BC  Music Credit: Matthew Bugos Thoughts? Suggestions? Email us at [email protected]  

Credits: 0.25 AMA PRA Category 1 Credit™   CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-446 Overview: Overwhelmed by in-basket tasks? Discover a practical scheduling intervention that gives you time during the clinic day to manage portal messages. Learn how “portal practice slots” can reduce burnout, improve workflow, and empower you to advocate for changes that support sustainable, high-quality primary care. Episode resource links: J Gen Intern Med. DOI: 10.1007/s11606-025-09582-8 Guest: Robert A. Baldor MD, FAAFP Music Credit: Matthew Bugos Thoughts? Suggestions? Email us at [email protected]  

Credits: 0.25 AMA PRA Category 1 Credit™   CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-445 Overview: Managing knee osteoarthritis (OA) in patients with obesity can be challenging, especially when standard treatments fall short. In this episode, we discuss emerging evidence on the use of metformin to reduce knee pain in patients without diabetes and explore how this option could expand your approach to OA management. Episode resource links: Pan F, Wang Y, Lim YZ, et al. Metformin for Knee Osteoarthritis in Patients With Overweight or Obesity: A Randomized Clinical Trial. JAMA. 2025;333(20):1804-1812.  Guest: Alan M. Ehrlich, MD, FAAFP   Music Credit: Matthew Bugos Thoughts? Suggestions? Email us at [email protected]   

Credits: 0.25 AMA PRA Category 1 Credit™   CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-444 Overview: An estimated 30% of women worldwide are affected by bacterial vaginosis (BV), and although treatment is typically successful, recurrence rates remain high. Traditional strategies, such as treating male partners, have not significantly reduced recurrence. In this episode, we discuss a recent study that used a new approach to partner treatment and review its potential to reduce BV recurrence. Episode resource links: Vodstrcil LA, Plummer EL, Fairley CK, et al. Male-partner treatment to prevent bacterial vaginosis.  The New England Journal of Medicine. 2025; 392 (10): 947-957. doi: 10.1056/NEJMoa2405404. DynaMed: https://www-dynamed-com.umassmed.idm.oclc.org/condition/bacterial-vaginosis-bv#GUID-E1A22CF7-D0AC-4247-B1F8-54D1CD26FC1A Guest: Susan Feeney, DNP, FNP   Music Credit: Matthew Bugos Thoughts? Suggestions? Email us at [email protected]   

Credits: 0.25 AMA PRA Category 1 Credit™   CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-443 Overview: In this episode, we evaluate the correlation between an increase in physical activity and step count and a reduction in cancer risk. We break down new evidence, equipping you with practical guidance for counseling patients on simple, impactful behavior changes to support long-term health. Episode resource links: Shreves AH, Small SR, Walmsley R, et al. Amount and intensity of daily total physical activity, step count and risk of incident cancer in the UK Biobank. Br J Sports Med. Published online 2025. doi:10.1136/bjsports-2024-109360 Islami, F., Goding Sauer, A., Miller, K.D., Siegel, R.L., Fedewa, S.A., Jacobs, E.J., McCullough, M.L., Patel, A.V., Ma, J., Soerjomataram, I., Flanders, W.D., Brawley, O.W., Gapstur, S.M. and Jemal, A. (2018), Proportion and number of cancer cases and deaths attributable to potentially modifiable risk factors in the United States. CA: A Cancer Journal for Clinicians, 68: 31-54. https://doi.org/10.3322/caac.21440 Guest: Jillian Joseph, PA-C   Music Credit: Matthew Bugos Thoughts? Suggestions? Email us at [email protected]   

Credits: 0.25 AMA PRA Category 1 Credit™   CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-442 Overview: Listen in as we review the USPSTF’s recently proposed recommendations for screening women who are at risk for developing osteoporosis. Gain confidence to navigate these changes and engage patients in shared decision-making to ensure timely, evidence-based preventive care. Episode resource links: JAMA. 2025;333(6):498–508. doi:10.1001/jama.2024.27154 Guest: Robert A. Baldor MD, FAAFP   Music Credit: Matthew Bugos Thoughts? Suggestions? Email us at [email protected]  

Credits: 0.25 AMA PRA Category 1 Credit™   CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-441 Overview: Explore the evidence behind inspiratory and expiratory strength training to improve sleep quality, reduce daytime fatigue, ease COPD symptoms, and lower blood pressure. This episode offers practical guidance on how you can integrate this simple, affordable intervention to support better breathing and overall health in your patients. Episode resource links: OSA: Journal of Sleep Research. 2024;33(3):e13941. doi:10.1111/jsr.13941. Sleep & Breathing = Schlaf & Atmung. 2022;26(4):1527-1537. doi:10.1007/s11325-021-02536-4. HTN: Journal of Applied Physiology (Bethesda, Md. : 1985). 2020;129(3):449-458. doi:10.1152/japplphysiol.00024.2020. COPD: Chest. 2003;124(4):1357-64. doi:10.1378/chest.124.4.1357. Sleep: Sleep. 2016;39(6):1179-85. doi:10.5665/sleep.5826. Guest: Robert A. Baldor MD, FAAFP   Music Credit: Matthew Bugos Thoughts? Suggestions? Email us at [email protected]  

Credits: 0.25 AMA PRA Category 1 Credit™   CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-440 Overview: Explore current and emerging treatments for myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS), a debilitating condition with no known cause or cure. Learn how oxaloacetate may offer new hope for patients struggling with ME/CFS, and gain practical guidance to support informed, evidence-based conversations with your patients. Episode resource links: Cash A, Vernon SD, Rond C, Bateman L, et al. RESTORE ME: a RCT of oxaloacetate for improving fatigue in patients with myalgic encephalomyelitis/chronic fatigue syndrome. Front Neurol. 2024 Nov 27;15:1483876.  Cash A, Kaufman DL. Oxaloacetate Treatment For Mental And Physical Fatigue In Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) and Long-COVID fatigue patients: a non-randomized controlled clinical trial. J Transl Med. 2022 Jun 28;20(1):295.  CDC ME/CFS Basics Myalgic Encephalomyelitis/Chronic Fatigue Syndrome Guest: Alan M. Ehrlich, MD, FAAFP   Music Credit: Matthew Bugos Thoughts? Suggestions? Email us at [email protected]  

Credits: 0.25 AMA PRA Category 1 Credit™   CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-439 Overview: Nocturnal leg cramps (NLCs) are common in older adults, but current treatments often fall short or carry risks. Listen in as we explore new evidence on the safety and efficacy of vitamin K2 as a potential treatment for NLCs. Come away with practical insights to help you improve the sleep and quality of life of your patients. Episode resource links: JAMA Intern Med. 2024;184(12):1443-1447. doi:10.1001/jamainternmed.2024.5726 Guest: Robert A. Baldor MD, FAAFP   Music Credit: Matthew Bugos Thoughts? Suggestions? Email us at [email protected]  

Credits: 0.25 AMA PRA Category 1 Credit™   CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-438 Overview: In this episode, we review a major umbrella study linking physical activity to improvements in memory, executive function, and general cognition—offering you practical insights to guide patient counseling and provide evidence-based, nonpharmacologic strategies for dementia prevention and cognitive enhancement. Episode resource links: Singh B, Bennett H, Miatke A, et al. Br J Sports Med. doi:10.1136/ Guest: Robert A. Baldor MD, FAAFP   Music Credit: Matthew Bugos Thoughts? Suggestions? Email us at [email protected]  

Credits: 0.25 AMA PRA Category 1 Credit™   CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-437 Overview: This episode reviews the remarkable impact of the human papillomavirus (HPV) vaccine from 2008–2022, including significant declines in cervical precancer rates. Tune in for key data insights and updated HPV vaccination guidelines to help you close care gaps and strengthen cancer prevention efforts in your practice. Episode resource links: Gargano JW, Stefanos R, Dahl RM, et al. Trends in Cervical Precancers Identified Through Population-Based Surveillance — Human Papillomavirus Vaccine Impact Monitoring Project, Five Sites, United States, 2008–2022. MMWR Morb Mortal Wkly Rep 2025;74:96–101. DOI: http://dx.doi.org/10.15585/mmwr.mm7406a4 • HPV Vaccination Recommendations: Dosing and Schedule • Talking to parents about HPV vaccine Guest: Jill M. Terrien PhD, ANP-BC    Music Credit: Matthew Bugos Thoughts? Suggestions? Email us at [email protected]   

Credits: 0.25 AMA PRA Category 1 Credit™   CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-436 Overview: Many patients with chronic obstructive pulmonary disease (COPD) are improperly treated with inhaled corticosteroids (ICS), increasing their risk of harm. This episode explores the latest evidence on long-term ICS risks and provides practical guidance to help you align COPD care with current guidelines—improving outcomes while minimizing adverse effects like pneumonia, cataracts, type 2 diabetes mellitus, and osteoporosis. Episode resource links: Pace WD, Callen E, Gaona-Villarreal G, Shaikh A, Yawn BP. Adverse outcomes associated with inhaled corticosteroid use in individuals with chronic obstructive pulmonary disease. Ann Fam Med. 2025;23(2):127-135. doi:10.1370/afm.240030 Pocket Guide to COPD Diagnosis, Management, and Prevention: A Guide for Healthcare Professionals. 2025 Edition. Global Initiative for Chronic Obstructive Lung Disease. https://goldcopd.org/2025-gold-report/ Guest: Jillian Joseph, PA-C   Music Credit: Matthew Bugos Thoughts? Suggestions? Email us at [email protected]   

Credits: 0.25 AMA PRA Category 1 Credit™   CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-435 Overview: In this episode, we discuss how screen time—from adolescence through adulthood—can disrupt sleep more than we might realize. Hear what the latest research says about topics like blue light and sleep duration, discover practical strategies to sleep smarter in this digital world, and learn how sleep deprivation can impact the health of your patients. Episode resource links: Zhong, C., Masters, M., Donzella, S. M., Diver, W. R., & Patel, A. V. (2025). Electronic Screen Use and Sleep Duration and Timing in Adults. JAMA Network Open, 8(3), e252493-e252493. Liu, Y. (2016). Prevalence of healthy sleep duration among adults—United States, 2014. MMWR. Morbidity and mortality weekly report, 65. Centers for Disease Control and Prevention (CDC). (2017). Announcement: sleep awareness week, April 23–29, 2017. Morb Mortal Wkly Rep (MMWR), 66(15), 411. Chaput, J. P., Dutil, C., Featherstone, R., Ross, R., Giangregorio, L., Saunders, T. J., ... & Carrier, J. (2020). Sleep duration and health in adults: an overview of systematic reviews. Applied Physiology, Nutrition, and Metabolism, 45(10), S218-S231. Hartley, S., Royant-Parola, S., Zayoud, A., Gremy, I., & Matulonga, B. (2022). Do both timing and duration of screen use affect sleep patterns in adolescents?. Plos one, 17(10), e0276226. Salfi, F., Amicucci, G., Corigliano, D., D’Atri, A., Viselli, L., Tempesta, D., & Ferrara, M. (2021). Changes of evening exposure to electronic devices during the COVID-19 lockdown affect the time course of sleep disturbances. Sleep, 44(9), zsab080. He, J. W., Tu, Z. H., Xiao, L., Su, T., & Tang, Y. X. (2020). Effect of restricting bedtime mobile phone use on sleep, arousal, mood, and working memory: a randomized pilot trial. PloS one, 15(2), e0228756. Guest: Mariyan L. Montaque, DNP, FNP-BC   Music Credit: Matthew Bugos Thoughts? Suggestions? Email us at [email protected]   

Credits: 0.25 AMA PRA Category 1 Credit™   CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-434 Overview: Is butter back on the menu? This episode breaks down a recent study on butter consumption and mortality risk, examines the origins of saturated fat concerns, and offers patient-centered guidance. Gain practical tools to address outdated nutrition beliefs and guide patients toward realistic, heart-healthy dietary choices rooted in the latest evidence. Episode resource links: JAMA Intern Med. Published online March 6, 2025. doi:10.1001/jamainternmed.2025.0205 PLoS One 2016 Jun 29;11(6):e0158118. doi: 10.1371/journal.pone.0158118 Guest: Robert A. Baldor MD, FAAFP   Music Credit: Matthew Bugos Thoughts? Suggestions? Email us at [email protected]   

Credits: 0.25 AMA PRA Category 1 Credit™   CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-433 Overview: E-cigarette use has risen significantly, especially among adolescents and young adults. Many people begin vaping alongside conventional cigarettes in an effort to quit or reduce smoking. But risks are emerging, challenging the belief that vaping is safer than combustible cigarettes. Join us as we explore the latest evidence on vaping, dual use, and the associated health risks. Episode resource links: Hamoud J, Hanewinkel R, Andreas S, et al. A Systematic Review Investigating the Impact of Dual Use of E-Cigarettes and Conventional Cigarettes on Smoking Cessation. ERJ Open Res 2024; in press (https://doi.org/10.1183/23120541.00902-2024). Lindson N, Butler AR, McRobbie H, et al. Electronic cigarettes for smoking cessation. Cochrane Database Syst Rev. 2024;1(1):CD010216. Published 2024 Jan 8. doi:10.1002/14651858.CD010216.pub8 Pisinger C, Rasmussen SKB. The Health Effects of Real-World Dual Use of Electronic and Conventional Cigarettes versus the Health Effects of Exclusive Smoking of Conventional Cigarettes: A Systematic Review. Int J Environ Res Public Health. 2022;19(20):13687. Published 2022 Oct 21. doi:10.3390/ijerph192013687 Nabbout, M. RSNA Press Release: Vaping Causes Immediate Effects on Vascular Function.  NIH-funded studies show damaging effects of vaping, smoking on blood vessels.  Kramarow, EA & Elgaddal, MS. Current Electorinc Cigarette Use Amoing Adults Aged 19 and Over: US, 2021. NCHS Data Brief, #475, Juky 2023.  CDC/NCHS Data: https://www.cdc.gov/nchs/fastats/smoking.htm Guest: Susan Feeney, DNP, FNP-BC, NP-C   Music Credit: Matthew Bugos Thoughts? Suggestions? Email us at [email protected]  

Credits: 0.25 AMA PRA Category 1 Credit™   CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-432 Overview: With measles outbreaks on the rise in the United States and globally, it’s important to skillfully recognize cases and effectively promote vaccination. This episode offers practical tips to identify measles and support patient conversations, helping you protect individual patients and strengthen community health. Episode resource links: CDC Health Alert Network, March 7, 2025 CDC Measles (Rubeola) UNICEF press release Guest: Alan M. Ehrlich, MD, FAAFP  Music Credit: Matthew Bugos Thoughts? Suggestions? Email us at [email protected]   

Credits: 0.25 AMA PRA Category 1 Credit™   CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-431 Overview: Tune in as we discuss the updated WHO and CDC hepatitis B guidelines, specifically focusing on screening, vaccination, and management. Learn how to apply these recommendations in clinical practice to support the WHO’s goal to eliminate hepatitis B by 2030. Guest: Mariyan L. Montaque, DNP, FNP-BC   Music Credit: Matthew Bugos Thoughts? Suggestions? Email us at [email protected] 

Credits: 0.25 AMA PRA Category 1 Credit™   CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-430 Overview: Stay up to date with the latest evidence-based acne treatment guidelines from the American Academy of Dermatology (AAD). Learn how to optimize topical and oral therapies, minimize antibiotic resistance, and apply new best practices to improve outcomes for adolescents and young adults. Don’t miss these key updates for enhancing patient care. Episode resource links: J Am Acad Dermatol 2024;90:1006.e1-30. doi.org/10.1016/j.jaad.2023.12.017 Guest: Robert A. Baldor MD, FAAFP   Music Credit: Matthew Bugos Thoughts? Suggestions? Email us at [email protected]   

Credits: 0.25 AMA PRA Category 1 Credit™   CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-429 Overview: Colorectal cancer screening saves lives, yet many patients remain unscreened. This episode explores current screening methods, the evidence behind the new DNA blood test, and how it compares to existing options. Gain practical insights to guide patient discussions and improve screening rates in your practice. Episode resource links: N Engl J Med. 2024 Mar 14;390(11):973-983. doi: 10.1056/NEJMoa2304714 N Engl J Med 2024;390:984-93. DOI: 10.1056/NEJMoa2310336 Guest: Jillian Joseph, MPAS, PA-C Music Credit: Matthew Bugos Thoughts? Suggestions? Email us at [email protected]   

Credits: 0.25 AMA PRA Category 1 Credit™   CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-428 Overview: Stay ahead in stroke prevention with the latest guidelines. In this episode, we cover new considerations for social determinants of health, interventions across the lifespan, and evidence-based strategies to reduce stroke risk. Learn how to integrate these updates into primary care for more effective patient outcomes. Episode resource links: Bushnell, C., Kernan, W. N., Sharrief, A. Z., Chaturvedi, S., Cole, J. W., Cornwell, W. K., 3rd, Cosby-Gaither, C., Doyle, S., Goldstein, L. B., Lennon, O., Levine, D. A., Love, M., Miller, E., Nguyen-Huynh, M., Rasmussen-Winkler, J., Rexrode, K. M., Rosendale, N., Sarma, S., Shimbo, D., Simpkins, A. N., … Whelton, P. K. (2024). 2024 Guideline for the Primary Prevention of Stroke: A Guideline From the American Heart Association/American Stroke Association. Stroke, 55(12), e344–e424. https://doi.org/10.1161/STR.0000000000000475 Ravichandran, S., Gajjar, P., Walker, M. E., Prescott, B., Tsao, C. W., Jha, M., Rao, P., Miller, P., Larson, M. G., Vasan, R. S., Shah, R. V., Xanthakis, V., Lewis, G. D., & Nayor, M. (2024). Life's Essential 8 Cardiovascular Health Score and Cardiorespiratory Fitness in the Community. Journal of the American Heart Association, 13(9), e032944. https://doi.org/10.1161/JAHA.123.032944 Kumar, M., Orkaby, A., Tighe, C., Villareal, D. T., Billingsley, H., Nanna, M. G., Kwak, M. J., Rohant, N., Patel, S., Goyal, P., Hummel, S., Al-Malouf, C., Kolimas, A., Krishnaswami, A., Rich, M. W., Kirkpatrick, J., Damluji, A. A., Kuchel, G. A., Forman, D. E., & Alexander, K. P. (2023). Life's Essential 8: Optimizing Health in Older Adults. JACC. Advances, 2(7), 100560. https://doi.org/10.1016/j.jacadv.2023.100560 Life’s Essential 8 tools for providers and patient information: https://www.heart.org/en/healthy-living/healthy-lifestyle/lifes-essential-8 Guest: Jill M. Terrien PhD, ANP-BC   Music Credit: Matthew Bugos Thoughts? Suggestions? Email us at [email protected]   

Credits: 0.25 AMA PRA Category 1 Credit™   CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-427 Overview: Discover how to optimize hypertension management with evidence-based exercise prescriptions. This episode reviews a large-scale meta-analysis on the effectiveness of various exercise routines for lowering blood pressure, helping you confidently integrate nonpharmacologic strategies into patient care. Learn which exercises work best and when to recommend them for improved cardiovascular health. Episode resource links: Edwards JJ, Deenmamode AHP, Griffiths M, et al. Br J Sports Med 2023;57:1317–1326. Guest: Robert A. Baldor MD, FAAFP   Music Credit: Matthew Bugos Thoughts? Suggestions? Email us at [email protected]  

Credits: 0.25 AMA PRA Category 1 Credit™   CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-426 Overview: Drinking coffee offers potential health benefits—but does timing affect outcomes? This episode dives into new research on how morning vs. all-day coffee consumption impacts cardiovascular disease and all-cause mortality risk. Gain practical insights to optimize patient recommendations based on the latest evidence. Episode resource links: European Heart Journal (2025) 00, 1–11 https://doi.org/10.1093/eurheartj/ehae871 The Journal of Clinical Endocrinology & Metabolism, 2024, 00, 1–11 https://doi.org/10.1210/clinem/dgae552 Guest: Jillian Joseph, MPAS, PA-C   Music Credit: Matthew Bugos Thoughts? Suggestions? Email us at [email protected]  

Credits: 0.25 AMA PRA Category 1 Credit™   CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-425 Overview: In this episode we discuss updates on the treatment and management of obstructive sleep apnea (OSA). This is a common health concern, but it is often underdiagnosed and can have significant health impacts. We review its prevalence and standard treatments, highlighting the recently used medication therapy that has been found to be effective in treating OSA, particularly in individuals with obesity.  Episode resource links: https://www.aafp.org/pubs/afp/issues/2023/0300/uspstf-obstructive-sleep-apnea.html https://emedicine.medscape.com/article/295807-overview Malhotra, A., Grunstein, R. R., Fietze, I., Weaver, T. E., Redline, S., Azarbarzin, A., ... & Bednarik, J. (2024). Tirzepatide for the Treatment of Obstructive Sleep Apnea and Obesity. New England Journal of Medicine. Mangione, C. M., Barry, M. J., Nicholson, W. K., Cabana, M., Chelmow, D., Coker, T. R., ... & US Preventive Services Task Force. (2022). Screening for obstructive sleep apnea in adults: US Preventive Services Task Force recommendation statement. Jama, 328(19), 1945-1950. https://aasm.org/rising-prevalence-of-sleep-apnea-in-u-s-threatens-public-health/ Guest: Mariyan L. Montaque, DNP, FNP-BC  Music Credit: Matthew Bugos Thoughts? Suggestions? Email us at [email protected]  

Credits: 0.25 AMA PRA Category 1 Credit™   CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-424   Overview: Urinary tract infections (UTIs) are one of the most common infections seen in primary care. In this episode, we discuss the latest guidelines addressing the diagnosis, treatment, and prevention of UTIs. Tune in to enhance your clinical expertise and provide superior care to your patients with UTIs.   Episode resource links: Nelson Z, Aslan AT, Beahm NP, et al. Guidelines for the Prevention, Diagnosis, and Management of Urinary Tract Infections in Pediatrics and Adults: A WikiGuidelines Group Consensus Statement. JAMA Netw Open. 2024 Nov 4;7(11):e2444495   Guest: Alan M. Ehrlich, MD, FAAFP   Music Credit: Matthew Bugos   Thoughts? Suggestions? Email us at [email protected] 

Credits: 0.25 AMA PRA Category 1 Credit™   CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-423 Overview: The use of electronic devices has increased across all ages, cultures, and socio-economic levels. Usage was also affected by the COVID-19 pandemic. There is a growing body of evidence that screen time can impact cognition and executive function in developing minds, and both the American Academy of Pediatrics (AAP) and the WHO have recommendations on screen time exposure for children. Join us as we discuss recent evidence looking at the impact of screentime on toddlers’ cognition and executive function over time.  Episode resource links: Fitzpatrick, C., Florit, E., Lemieux, A., Garon-Carrier, G, Mason, L. Associations between preschooler screentime trajectories and executive function. Academic Pediatrics, Volume 0, Issue 0, 102603. Schmidt-Persson J, Rasmussen MGB, Sørensen SO, et al. Screen Media Use and Mental Health of Children and Adolescents: A Secondary Analysis of a Randomized Clinical Trial. JAMA Netw Open. 2024;7(7):e2419881. doi:10.1001/jamanetworkopen.2024.19881 AAP Screen Time Guidelines Schmidt-Persson J, Rasmussen MGB, Sørensen SO, et al. Screen Media Use and Mental Health of Children and Adolescents: A Secondary Analysis of a Randomized Clinical Trial. JAMA Netw Open. 2024;7(7):e2419881. doi:10.1001/jamanetworkopen.2024.19881 Raj D, Ahmad N, Mohd Zulkefli NA, Lim PY. Stop and Play Digital Health Education Intervention for Reducing Excessive Screen Time Among Preschoolers From Low Socioeconomic Families: Cluster Randomized Controlled Trial. J Med Internet Res. 2023;25:e40955. Published 2023 May 4. doi:10.2196/40955 Guest: Susan Feeney, DNP, FNP-BC, NP-C Music Credit: Matthew Bugos Thoughts? Suggestions? Email us at [email protected]   

Credits: 0.25 AMA PRA Category 1 Credit™   CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-422 Overview: Conflicting data on alcohol’s health effects leave clinicians uncertain about patient guidance. In this episode, we review the PREDIMED trial’s findings on wine and cardiovascular outcomes, explore objective biomarkers for intake, and examine the National Academy of Sciences’ recent report to clarify the risks and benefits of moderate consumption, giving you confidence in counseling patients. Episode resource links: Inés Domínguez-López, Rosa M Lamuela-Raventós, Cristina Razquin, et al. Urinary tartaric acid as a biomarker of wine consumption and cardiovascular risk: the PREDIMED trial, European Heart Journal, 2024;, ehae804, https://doi.org/10.1093/eurheartj/ehae804     National Academies of Sciences, Engineering, and Medicine. 2025. Review of Evidence on Alcohol and Health. Washington, DC: The National Academies Press. https://doi.org/10.17226/28582   Guest: Robert A. Baldor MD, FAAFP Music Credit: Matthew Bugos Thoughts? Suggestions? Email us at [email protected]  

Credits: 0.25 AMA PRA Category 1 Credit™   CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-421 Overview: Join us as we discuss a recent meta-analysis examining randomized controlled trials to investigate healthcare costs, quality of care, and patient well-being when delivered by advanced nurse practitioners (ANPs). Explore the evidence behind ANPs’ effectiveness and their potential to enhance patient outcomes while optimizing healthcare resources. Episode resource links: Melati Fajarini, Agus Setiawan, Chien-Mei Sung, Ruey Chen, Doresses Liu, Chiu-Kuei Lee, Shu-Fen Niu, Kuei-Ru Chou, Effects of advanced practice nurses on health-care costs, quality of care, and patient well-being: A meta-analysis of randomized controlled trials, International Journal of Nursing Studies, Volume 162, 2025,104953, ISSN 0020-7489, https://doi.org/10.1016/j.ijnurstu.2024.104953 The miseducation of America’s nurse practitioners, July 24, 2024      Perloff, J., Clarke, S., DesRoches, C. M., O'Reilly-Jacob, M., & Buerhaus, P. (2019). Association of State-Level Restrictions in Nurse Practitioner Scope of Practice With the Quality of Primary Care Provided to Medicare Beneficiaries. Medical care research and review : MCRR, 76(5), 597–626. https://doi.org/10.1177/1077558717732402   Yang, B. K., Johantgen, M. E., Trinkoff, A. M., Idzik, S. R., Wince, J., & Tomlinson, C. (2021). State Nurse Practitioner Practice Regulations and U.S. Health Care Delivery Outcomes: A Systematic Review. Medical care research and review : MCRR, 78(3), 183–196. https://doi.org/10.1177/1077558719901216   Taylor K (2023) Bridging the Gap to Health Care Access: The Role of the Nurse Practitioner. Int Arch Public Health Community Med 7:091. doi.org/10.23937/2643-4512/1710091 Guest: Susan Feeney, DNP, FNP-BC, NP-C, Jill M. Terrien PhD, ANP-BC  Music Credit: Matthew Bugos Thoughts? Suggestions? Email us at [email protected]  

Credits: 0.25 AMA PRA Category 1 Credit™   CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-420 Overview: Listen in as we discuss the US Surgeon General’s new advisory on the impact of alcohol on cancer incidence and mortality. We review the latest data, explore alcohol’s role in carcinogenesis, and provide evidence-based guidance to help you counsel patients on safer consumption and cancer prevention. Episode resource links: U.S. Surgeon General Issues New Advisory on Link Between Alcohol and Cancer Risk | HHS.gov Guest: Jillian Joseph, MPAS, PA-C Music Credit: Matthew Bugos Thoughts? Suggestions? Email us at [email protected]   

Credits: 0.25 AMA PRA Category 1 Credit™   CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-419 Overview: Water fluoridation has been an area of periodic controversy since it was first introduced in the 1950s. This episode dives into recent reports on the benefits and potential impacts of water fluoridation on children’s IQ. Gain valuable insights and feel prepared when addressing patient questions about this topic. Episode resource links: Taylor KW, Eftim SE, Sibrizzi CA, et al. Fluoride Exposure and Children’s IQ Scores: A Systematic Review and Meta-Analysis. JAMA Pediatr. Published online January 06, 2025.  Iheozor-Ejiofor Z, Walsh T, Lewis SR, Riley P, Boyers D, Clarkson JE, Worthington HV, Glenny AM, O'Malley L. Water fluoridation for the prevention of dental caries. Cochrane Database Syst Rev. 2024 Oct 4;10(10):CD010856.  Schluter PJ, Hobbs M, Atkins H, Mattingley B, Lee M. Association Between Community Water Fluoridation and Severe Dental Caries Experience in 4-Year-Old New Zealand Children. JAMA Pediatr. 2020 Oct 1;174(10):969-976 Guest: Alan M. Ehrlich, MD, FAAFP   Music Credit: Matthew Bugos Thoughts? Suggestions? Email us at [email protected]   

Credits: 0.25 AMA PRA Category 1 Credit™   CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-418 Overview: Acute episodes of nausea, vomiting, and diarrhea due to gastroenteritis in children are common complaints seen in primary and urgent care settings. Join us as we discuss recent evidence suggesting that apple juice can be as effective as commercial electrolyte solutions, offering a cost-effective and convenient option for oral replacement therapy for mild dehydration. Episode resource links: Freedman SB, Willan AR, Boutis K, Schuh S. Effect of Dilute Apple Juice and Preferred Fluids vs Electrolyte Maintenance Solution on Treatment Failure Among Children With Mild Gastroenteritis: A Randomized Clinical Trial. JAMA. 2016;315(18):1966-1974. doi:10.1001/jama.2016.5352 Goldman RD, Friedman JN, Parkin PC. Validation of the clinical dehydration scale for children with acute gastroenteritis. Pediatrics. 2008;122(3):545-549. doi:10.1542/peds.2007-3141 Jauregui J, Nelson D, Choo E, et al. External validation and comparison of three pediatric clinical dehydration scales. PLoS One. 2014;9(5):e95739. Published 2014 May 2. doi:10.1371/journal.pone.0095739 https://primarycarenotebook.com/pages/haematology/world-health-organization-who-scale-for-dehydration AAP: Signs of Dehydration in infant and children https://primarycarenotebook.com/pages/haematology/world-health-organization-who-scale-for-dehydration Guest: Susan Feeney, DNP, FNP-BC, NP-C  Music Credit: Matthew Bugos Thoughts? Suggestions? Email us at [email protected]   

Credits: 0.25 AMA PRA Category 1 Credit™   CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-417   Overview: Joseph is a 57 year old male who presents today for his routine annual exam. He is a healthy male, who is active and has no complaints today. He reports that since he was seen last he generally has been doing well but did have a ER visit for persistent cough in the setting of recovering from Covid. While in the Emergency Department he did undergo testing. On a CT Chest scan there was an incidental finding of moderate coronary artery calcifications.  He asked today, what does moderate coronary artery calcification? Is my heart ok, my dad had a heart attack at 60.    Episode resource links: https://www.who.int/news-room/fact-sheets/detail/cardiovascular-diseases-(cvds) https://odphp.health.gov/healthypeople/objectives-and-data/browse-objectives/heart-disease-and-stroke#:~:text=Heart%20disease%20and%20stroke%20can,and%20high%20cholesterol%20through%20treatment. Vikulova, D. N., Lee, M. K., Humphries, K. H., Pinheiro-Muller, D., Dawes, M., Pimstone, S. N., & Brunham, L. R. (2024). Preventive Lipid-Lowering Therapy and Interactions With Health Care in Patients Who Develop Premature Coronary Artery Disease. JACC: Advances, 101316.   Maron, D. J., Budoff, M. J., Sky, J. C., Bommer, W. J., Epstein, S. D., Fisher, D. A., ... & DeMaria, A. N. (2024). Coronary Artery Calcium Staging to Guide Preventive Interventions: A Proposal and Call to Action. JACC: Advances, 3(11), 101287. https://www.cdc.gov/heart-disease-family-history/about/index.html   Guest: Mariyan L. Montaque, DNP, FNP-BC   Music Credit: Matthew Bugos   Thoughts? Suggestions? Email us at [email protected] 

Credits: 0.25 AMA PRA Category 1 Credit™   CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-416 Overview: Listen in as we discuss chronic sacroiliac (SI) dysfunction and the role of nonpharmacological therapies, including acupuncture, in managing back pain and improving function. Hear evidence-based considerations for integrating acupuncture into your practice to offer effective, medication-free options for patients with chronic SI pain. Episode resource links: Kim G, Kim D, Moon H, et al. Acupuncture and Acupoints for Low Back Pain: Systematic Review and Meta-Analysis. Am J Chin Med. 2023;51(2):223-247. doi:10.1142/S0192415X23500131 Mu J, Furlan AD, Lam WY, Hsu MY, Ning Z, Lao L. Acupuncture for chronic nonspecific low back pain. Cochrane Database Syst Rev. 2020;12(12):CD013814. Published 2020 Dec 11. doi:10.1002/14651858.CD013814 Tu J-F et al. Acupuncture vs sham acupuncture for chronic sciatica from herniated disk: A randomized clinical trial. JAMA Intern Med 2024 Oct 14; [e-pub]. (https://doi.org/10.1001/jamainternmed.2024.5463) Wu M, Fan C, Liu H, et al. The Effectiveness of Acupuncture for Low Back Pain: An Umbrella Review and Meta-Analysis. Am J Chin Med. 2024;52(4):905-923. doi:10.1142/S0192415X2450037X https://www-dynamed-com.umassmed.idm.oclc.org/condition/sciatica Guest: Susan Feeney, DNP, FNP   Music Credit: Matthew Bugos Thoughts? Suggestions? Email us at [email protected]   

Credits: 0.25 AMA PRA Category 1 Credit™   CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-415 Overview: Join us as we discuss the role of postexposure prophylaxis (PEP) in reducing the incidence and adverse outcomes of sexually transmitted infections (STIs), including chlamydia, gonorrhea, and syphilis. Discover when, why, and how to prescribe PEP to better provide your patients with effective prevention options to help reduce rising STI rates and disproportionate impacts on women. Episode resource links: Stewart, J., Oware, K., Donnell, D., Violette, L. R., Odoyo, J., Soge, O. O., ... & Baeten, J. M. (2023). Doxycycline prophylaxis to prevent sexually transmitted infections in women. New England Journal of Medicine, 389(25), 2331-2340. https://www.cdc.gov/sti/php/from-the-director/doxy-pep-sti-prevention-strategy.html#:~:text=Doxy%20PEP%20has%20proven%20to,syphilis%2C%20chlamydia%2C%20gonorrhea). Guest: Mariyan L. Montaque, DNP, FNP-BC Music Credit: Matthew Bugos Thoughts? Suggestions? Email us at [email protected]   

Credits: 0.25 AMA PRA Category 1 Credit™   CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-414 Overview: Standing desks are a popular choice for people with sedentary jobs who want to increase their physical activity. In this episode, we look at the latest data on the benefits and risks of prolonged standing and provide actionable strategies to help patients reduce cardiovascular risk through informed movement choices. Episode resource links: Ahmadi MN, Coenen P, Straker L, Stamatakis E. Device-measured stationary behaviour and cardiovascular and orthostatic circulatory disease incidence. Int J Epidemiol. 2024 Oct 13;53(6):dyae136. doi: 10.1093/ije/dyae136. PMID: 39412356; PMCID: PMC11481281. Guest: Alan M. Ehrlich, MD, FAAFP  Music Credit: Matthew Bugos Thoughts? Suggestions? Email us at [email protected]   

Credits: 0.25 AMA PRA Category 1 Credit™   CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-413 Overview: Listen in to learn about the role of nicotinamide (vitamin B3) in reducing the risk of certain skin cancers. This episode reviews key prevention strategies, the latest evidence on skin cancer management, and practical approaches to support patients with sun-damaged skin. Episode resource links: Discuss the prevalence of basal cell and squamous cell carcinomas  Review the potential benefits of nicotinamide (vitamin B3) for the prevention of skin abnormalities Identify additional methods to prevent skin cancer Guest: Alan M. Ehrlich, MD, FAAFP   Music Credit: Matthew Bugos Thoughts? Suggestions? Email us at [email protected]   

Credits: 0.25 AMA PRA Category 1 Credit™   CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-412 Overview: Discover how improper arm positioning can lead to inaccurate blood pressure readings and influence hypertension management as we discuss a recent randomized controlled trial. Hear evidence-based techniques to ensure proper arm and cuff positioning, improving hypertension diagnosis in your clinical practice. Episode resource links: JAMA Intern Med. Published online October 7, 2024. doi:10.1001/jamainternmed.2024.5213 Guest: Robert A. Baldor MD, FAAFP Music Credit: Matthew Bugos Thoughts? Suggestions? Email us at [email protected]  

Credits: 0.25 AMA PRA Category 1 Credit™   CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-411 Overview: This episode focuses on the rising prevalence of early-onset colorectal cancer and its critical indicators. Learn to recognize key symptoms, ensure timely diagnostic workups, and effectively address red flags to prevent delayed diagnosis. Episode resource links: Demb, J., Kolb, J. M., Dounel, J., Fritz, C. D. L., Advani, S. M., Cao, Y., Coppernoll-Blach, P., Dwyer, A. J., Perea, J., Heskett, K. M., Holowatyj, A. N., Lieu, C. H., Singh, S., Spaander, M. C. W., Vuik, F. E. R., & Gupta, S. (2024). Red Flag Signs and Symptoms for Patients With Early-Onset Colorectal Cancer: A Systematic Review and Meta-Analysis. JAMA network open, 7(5), e2413157. https://doi.org/10.1001/jamanetworkopen.2024.13157 US Preventive Services Task Force Screening Guidelines for Colorectal Cancer: https://www.uspreventiveservicestaskforce.org/uspstf/recommendation/colorectal-cancer-screening American Cancer Society Infographic for Patients:  Colorectal Cancer:  Catching it Early https://www.cancer.org/cancer/types/colon-rectal-cancer/prevention-infographic.html Gómez-Molina R, Suárez M, Martínez R, Chilet M, Bauça JM, Mateo J. Utility of Stool-Based Tests for Colorectal Cancer Detection: A Comprehensive Review. Healthcare. 2024; 12(16):1645. https://doi.org/10.3390/healthcare12161645 Guest: Jill M. Terrien PhD, ANP-BC  Music Credit: Matthew Bugos Thoughts? Suggestions? Email us at [email protected]   

Credits: 0.25 AMA PRA Category 1 Credit™   CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-410 Overview: In this episode, we discuss the latest updates on vitamin D. Learn about its link to common disorders, when to consider supplementation, and what the most recent practice guideline says about vitamin D and disease prevention—empowering you to make informed decisions and improve patient care without unnecessary screenings or treatments. Episode resource links: Marie B Demay, Anastassios G Pittas, Daniel D Bikle, Dima L Diab, Mairead E Kiely, Marise Lazaretti-Castro, Paul Lips, Deborah M Mitchell, M Hassan Murad, Shelley Powers, Sudhaker D Rao, Robert Scragg, John A Tayek, Amy M Valent, Judith M E Walsh, Christopher R McCartney, Vitamin D for the Prevention of Disease: An Endocrine Society Clinical Practice Guideline, The Journal of Clinical Endocrinology & Metabolism, Volume 109, Issue 8, August 2024, Pages 1907–1947, https://doi.org/10.1210/clinem/dgae290 Michael F. Holick, Neil C. Binkley, Heike A. Bischoff-Ferrari, Catherine M. Gordon, David A. Hanley, Robert P. Heaney, M. Hassan Murad, Connie M. Weaver, Evaluation, Treatment, and Prevention of Vitamin D Deficiency: an Endocrine Society Clinical Practice Guideline, The Journal of Clinical Endocrinology & Metabolism, Volume 96, Issue 7, 1 July 2011, Pages 1911–1930, https://doi.org/10.1210/jc.2011-0385 Guest: Jillian Joseph, PA-C   Music Credit: Matthew Bugos Thoughts? Suggestions? Email us at [email protected]  

Credits: 0.25 AMA PRA Category 1 Credit™   CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-409 Overview: Listen in as we discuss how bright light therapy extends beyond seasonal affective disorder, potentially offering benefits for nonseasonal depression. Learn how to counsel patients effectively on its use and integrate this treatment into your practice, enhancing patient care and broadening treatment strategies for depression. Episode resource links: Menegaz de Almeida A, Aquino de Moraes FC, Cavalcanti Souza ME, Cavalcanti Orestes Cardoso JH, Tamashiro F, Miranda C, Fernandes L, Kreuz M, Alves Kelly F. Bright Light Therapy for Nonseasonal Depressive Disorders: A Systematic Review and Meta-Analysis. JAMA Psychiatry. 2024 Oct 2:e242871  Guest: Alan M. Ehrlich, MD, FAAFP   Music Credit: Matthew Bugos Thoughts? Suggestions? Email us at [email protected]   

Credits: 0.25 AMA PRA Category 1 Credit™   CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-408 Overview: This episode explores the connection between adolescent mental health and social media use. We discuss actionable strategies for clinicians, emphasizing practical screening, effective conversation starters, and tech tools to guide families. Improve outcomes by learning to balance screen time discussions and proactive mental health interventions in primary care. Episode resource links: JAMA Netw Open. 2024 Jul 1;7(7):e2419881. doi: 10.1001/jamanetworkopen.2024.19881 https://www.cdc.gov/healthyyouth/data/yrbs/yrbs_data_summary_and_trends.htm Guest: Alan M. Ehrlich, MD, FAAFP   Music Credit: Matthew Bugos Thoughts? Suggestions? Email us at [email protected]     

Credits: 0.25 AMA PRA Category 1 Credit™   CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-407 Overview: Join us as we review the risks and benefits of contraceptive options, focusing on levonorgestrel intrauterine devices (IUDs) and their potential link to breast cancer risk. Hear the data and key considerations to help patients make informed decisions, balancing benefits and risks effectively in your primary care practice. Episode resource links: Mørch LS, Meaidi A, Corn G, Hargreave M, Wessel Skovlund C. Breast Cancer in Users of Levonorgestrel-Releasing Intrauterine Systems. JAMA. Published online October 16, 2024. doi:10.1001/jama.2024.18575 https://www.nytimes.com/2024/10/16/well/iud-breast-cancer-mirena-skyla.html?smid=url-share Guest: Jillian Joseph, PA-C   Music Credit: Matthew Bugos Thoughts? Suggestions? Email us at [email protected]  

Credits: 0.25 AMA PRA Category 1 Credit™   CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-406 Overview: An increasing number of therapies are being formulated for nasal delivery. This episode reviews the use of 3 of these therapies: at-home flu vaccines, epinephrine for allergic reactions, and saline nasal sprays for the common cold. Hear how these newly available treatments can increase options for care in your clinical practice. Episode resource links: Flu Vaccine: Vaccine. 2015 Jul 31;33(32):3894-9.  doi: 10.1016/j.vaccine.2015.06.061. Epub 2015 Jun 25. Nasal Saline: https://k4.ersnet.org/prod/v2/Front/Program?e=549 Nasal Epinephrine: https://www.fda.gov/news-events/press-announcements/fda-approves-first-nasal-spray-treatment-anaphylaxis Guest: Robert A. Baldor MD, FAAFP  Music Credit: Matthew Bugos Thoughts? Suggestions? Email us at [email protected]   

Credits: 0.25 AMA PRA Category 1 Credit™   CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-405 Overview: Explore the American Heart Association’s (AHA) newly validated risk calculator, designed to assess the likelihood of cardiovascular disease and heart failure in patients aged 30-79 years. Hear which risk factors are included, why they matter, and how this tool can enhance your preventive care strategies in primary care practice. Episode resource links: Hypertension. 2024;81:00–00. DOI: 10.1161/HYPERTENSIONAHA.124.22998.) https://doi.org/10.1161/CIRCULATIONAHA.123.067626 The calculator: https://professional.heart.org/en/guidelines-and-statements/prevent-calculator Guest: Robert A. Baldor MD, FAAFP  Music Credit: Matthew Bugos Thoughts? Suggestions? Email us at [email protected]   

Credits: 0.25 AMA PRA Category 1 Credit™   CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-404 Overview: It’s estimated that between 40%-60% of women report some degree of sexual dysfunction, which can have a significant impact on an individual’s quality of life and personal relationships. Even though most clinicians understand the importance and relevance of female sexual dysfunction (FSD), they may not be aware of its prevalence, effective treatments, or how best to inquire about it. Join us as we discuss this condition, its impact on women, and evidence on effective treatments. Episode resource links: Cristine Homsi Jorge, Kari Bø, Camila Chiazuto Catai, Luiz Gustavo Oliveira Brito, Patricia Driusso, Merete Kolberg Tennfjord. Pelvic floor muscle training as treatment for female sexual dysfunction: a systematic review and meta-analysis. American Journal of Obstetrics and Gynecology. Volume 231, Issue 1, 2024,Pages 51-66.e1,ISSN 0002-9378, https://doi.org/10.1016/j.ajog.2024.01.001.(https://www.sciencedirect.com/science/article/pii/S0002937824000061) Davis, SR. Sexual dysfunction in women. New England Journal of Medicine. V 391. N 8; P 736-745. https://www.nejm.org/doi/full/10.1056/NEJMcp2313307 Johnson, Isabella MS; Thurman, Andrea Ries MD; Cornell, Katherine A. BS; Hatheway, Jessica MBA; Dart, Clint MS; Brainard, C. Paige MD; Friend, David R. PhD; Goldstein, Andrew MD. Preliminary Efficacy of Topical Sildenafil Cream for the Treatment of Female Sexual Arousal Disorder: A Randomized Controlled Trial. Obstetrics & Gynecology ():10.1097/AOG.0000000000005648, June 18, 2024. | DOI: 10.1097/AOG.0000000000005648 Kamrul-Hasan, A.B.M, Hannan, M A A, Muhammad S, M, Aalpona, Fatema, T Z, Nagendra, L., Selim, S,  Dutta, D, D. Role of flibanserin in managing hypoactive sexual desire disorder in women: A systematic review and meta-analysis. Medicine 103(25):p e38592, June 21, 2024. | DOI: 10.1097/MD.0000000000038592 Yao H, Zhang X, Sun F, Tang G, Wu J, Zhou Z. The efficacy of intravaginal electrical stimulation (IVES) in treating female with urinary incontinence symptom from meta-analysis of nine randomized controlled trials. Front Neurol. 2022;13:933679. Published 2022 Sep 13. doi:10.3389/fneur.2022.933679 Huang H, Ding G, Li M, Deng Y, Cheng Y, Jin H.(2023) Menopause and stress urinary incontinence: The risk factors of stress urinary incontinence in perimenopausal and postmenopausal women. J Obstet Gynaecol Res. 49(10): 2509–2518. https://doi.org/10.1111/jog.15742 Tunn, R., Baessler, K., Knüpfer, S., & Hampel, C. (2023). Urinary Incontinence and Pelvic Organ Prolapse in Women. Deutsches Arzteblatt international, 120(5), 71–80. https://doi.org/10.3238/arztebl.m2022.0406 Guest: Susan Feeney, DNP, FNP-BC, NP-C, Jill M. Terrien, PhD, ANP-BC Music Credit: Matthew Bugos Thoughts? Suggestions? Email us at [email protected]  

Credits: 0.25 AMA PRA Category 1 Credit™   CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-403 Overview: Recorded live at Pri-Med East! - The American Diabetes Association (ADA) has updated their standards of care for patients with diabetes. In this episode, we discuss some of the changes in the initial selection of glucose-lowering medications for type 2 diabetes mellitus (T2DM), including when alternatives to metformin may be appropriate. Hear strategies for making personalized, guideline-recommended choices that enhance care for patients with T2DM. Episode resource links: Pharmacologic Approaches to Glycemic Treatment. In: American Diabetes Association. Standardsof Care in Diabetes2024 - DiabetesCare 2024 Jan 1;47(Suppl 1):S1-S321 Guest: Alan M. Ehrlich, MD, FAAFP  Music Credit: Matthew Bugos Thoughts? Suggestions? Email us at [email protected]   

Credits: 0.25 AMA PRA Category 1 Credit™   CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-402 Overview: Some blood pressure medications have been found to cause adverse side effects in older adults, such as itchy skin and an increased risk of stroke. Join us as we cover 2 recent publications that add clinical implications to which blood pressure medications we use. Come away feeling confident to improve hypertension outcomes in older patients. Episode resource links: JAMA Dermatol. Published online May 22, 2024. doi:10.1001/jamadermatol.2024.1230 JAMA Netw Open. 2023;6(12):e2344998. doi:10.1001/jamanetworkopen.2023.44998 Guest: Robert A. Baldor MD, FAAFP Music Credit: Matthew Bugos Thoughts? Suggestions? Email us at [email protected]  

Credits: 0.25 AMA PRA Category 1 Credit™   CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-401 Overview: Evidence has shown that exercise can improve mood, but how successful is it for treating depression compared to other therapies? What types and intensities are most effective? Discover insights from a recent meta-analysis on the effects of exercise on depression and strategies to promote it in those with major depression. Episode resource links: Noetel M, Sanders T, Gallardo-Gómez D, Taylor P, del Pozo Cruz B, van den Hoek D et al. Effect of exercise for depression: systematic review and network meta-analysis of randomised controlled trials BMJ 2024; 384 :e075847 doi:10.1136/bmj-2023-075847 Vancampfort, D., Hallgren, M., Firth, J., Rosenbaum, S., Schuch, F. B., Mugisha, J., Probst, M., Van Damme, T., Carvalho, A. F., & Stubbs, B. (2017). Physical activity and suicidal ideation: a systematic review and meta-analysis. Journal of Affective Disorders. https://doi.org/10.1016/j.jad.2017.08.070 Guest: Susan Feeney, DNP, FNP-BC, NP-C Music Credit: Matthew Bugos Thoughts? Suggestions? Email us at [email protected]  

Credits: 0.25 AMA PRA Category 1 Credit™   CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-400 Overview: The FDA recently approved primary human papillomavirus (HPV) self-collection for cervical cancer screening in a healthcare setting. Join us as we explore how to counsel patients on this less invasive method and find out what’s on the horizon for at-home collection kits. Episode resource links: https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfpma/pma.cfm?id=P160037 Journal of Clinical Virology, 2020-06-01, Volume 127, Article 104375, Copyright © 2020 Elsevier B.V.  JAMA. 2023;330(20):1971-1981. doi:10.1001/jama.2023.21471 Guest: Robert A. Baldor MD, FAAFP Music Credit: Matthew Bugos Thoughts? Suggestions? Email us at [email protected]  

Credits: 0.25 AMA PRA Category 1 Credit™   CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-399 Overview: In this episode, we look at a new study showing increased probability of survival for patients with Alzheimer disease (AD) who take donepezil and memantine together. We review current treatments for AD and address common hesitations in prescribing dual pharmacotherapy, providing vital insights for primary care clinicians. Episode resource links: Yaghmaei, E., Lu, H., Ehwerhemuepha, L. et al. Combined use of Donepezil and Memantine increases the probability of five-year survival of Alzheimer’s disease patients.Commun Med 4, 99 (2024). https://doi.org/10.1038/s43856-024-00527-6 Guo J, Wang Z, Liu R, Huang Y, Zhang N, Zhang R. Memantine, Donepezil, or Combination Therapy-What is the best therapy for Alzheimer's Disease? A Network Meta-Analysis. Brain Behav. 2020 Nov;10(11):e01831. doi: 10.1002/brb3.1831. Epub 2020 Sep 10. PMID: 32914577; PMCID: PMC7667299. Guest: Jillian Joseph, MPAS, PA-C Music Credit: Matthew Bugos Thoughts? Suggestions? Email us at [email protected]   

Credits: 0.25 AMA PRA Category 1 Credit™   CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-398 Overview: Low back pain is the leading cause of years lived with disability, with approximately 70% of individuals experiencing a recurrence within 12 months following recovery from an episode. Clinicians are poised to play a crucial role in encouraging patients to incorporate walking to prevent recurrences of low back pain. Episode resource links: Pocovi NC, Lin CC, French SD, Graham PL, van Dongen JM, Latimer J, Merom D, Tiedemann A, Maher CG, Clavisi O, Tong SYK, Hancock MJ. Effectiveness and cost-effectiveness of an individualised, progressive walking and education intervention for the prevention of low back pain recurrence in Australia (WalkBack): a randomised controlled trial. Lancet. 2024 Jun 19:S0140-6736(24)00755-4. PMID: 38908392. Guest: Alan M. Ehrlich, MD, FAAFP  Music Credit: Richard Onorato Thoughts? Suggestions? Email us at [email protected]   

Credits: 0.25 AMA PRA Category 1 Credit™   CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-397 Overview: In this episode, we review the T Trials—a coordinated set of 7 research trials that assessed the efficacy of testosterone gel treatment in 7 functional domains for men aged 65 years or older. Hear best practices for determining testosterone levels and how to balance the benefits and risks of testosterone replacement therapy during patient discussions. Episode resource links: Matsumoto AM. Testosterone Replacement in Men with Age-Related Low Testosterone: What Did We Learn From The Testosterone Trials? Curr Opin Endocr Metab Res. 2019 Jun;6:34-41. doi: 10.1016/j.coemr.2019.04.004. Epub 2019 Apr 25. PMID: 32043015; PMCID: PMC7009797.  The Journal of Clinical Endocrinology & Metabolism, 2024, 00, 1–10 https://doi.org/10.1210/clinem/dgae085 Guest: Robert A. Baldor MD, FAAFP Music Credit: Richard Onorato Thoughts? Suggestions? Email us at [email protected]  

Credits: 0.25 AMA PRA Category 1 Credit™   CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-396 Overview: Listen in as we discuss the health risks of e-cigarette use and dual use, emphasizing the importance of primary prevention and supporting patients in their cessation efforts. Discover the latest evidence on vaping’s impact on addiction, cardiovascular health, and lung cancer, and gain essential insights to better advise your patients. Episode resource links: Bittoni MA, et al. Abstract 2213. Presented at: American Association for Cancer Research Annual Meeting; April 5-10, 2024; San Diego. (AACR 2024: Ohio State experts share new findings at annual meeting (press release). Available at: https://cancer.osu.edu/news/aacr-2024-ohio-state-experts-share-new-findings. Posted April 5,2024. Accessed May 3, 2024.) Hartmann-Boyce J, McRobbie H, Lindson N, et al. Electronic cigarettes for smoking cessation. Cochrane Database Syst Rev. Apr 29 2021;4:CD010216. doi:10.1002/14651858.CD010216.pub5 Hopkinson NS, et al "Association of time spent on social media with youth cigarette smoking and e-cigarette use in the UK: a national longitudinal study" Thorax 2024: DOI:10.1136/ thorax-2023-220569. Y.W. Kim, E.J. Park, K.I. Kwak, A.-R. Choi, B.J. Lee, Y.J. Lee, J.S. Park, Y.-J. Cho, J.H. Lee, and C.-T. Lee. Association of Electronic Cigarette Use After Conventional Smoking Cessation With Lung Cancer Risk: A Nationwide Cohort Study (abstract). Am J Respir Crit Care Med 2024;209:A3051. CDC: Health Effects of Vaping; https://www.cdc.gov/tobacco/e-cigarettes/health-effects.html CDC:Dual Use of Tobacco Products; https://www.cdc.gov/tobacco/campaign/tips/diseases/dual-tobacco-use.html Guest: Susan Feeney, DNP, FNP-BC, NP-C  Music Credit: Richard Onorato Thoughts? Suggestions? Email us at [email protected]  

Credits: 0.25 AMA PRA Category 1 Credit™   CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-395 Overview: This episode brings you an exploration of fish oil supplements and their potential effects on cardiovascular health. We dive into the evidence, highlighting fish oil’s role in primary prevention and its possible risks, such as increased atrial fibrillation. Gain practical recommendations to help you effectively advise your patients on the use of this popular supplement. Episode resource links: Regular use of fish oil supplements and course of cardiovascular diseases: prospective cohort study BMJ Medicine 2024;3:e000451. doi: 10.1136/bmjmed-2022-000451 Omega-3 Polyunsaturated Fatty Acid (Fish Oil) Supplementation and the Prevention of Clinical Cardiovascular Disease:  A Science Advisory From the American Heart Association Circulation. 2017;135:e867–e884 Guest: Robert A. Baldor MD, FAAFP  Music Credit: Richard Onorato Thoughts? Suggestions? Email us at [email protected]  

Credits: 0.25 AMA PRA Category 1 Credit™   CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-394 Overview: Explore the keys to confidently promoting healthy aging in patients. In this insightful conversation, we identify behaviors impacting longevity and discuss practical steps to minimize risks, including diet, exercise, and sleep. Discover evidence-based insights on how even light physical activity can significantly improve patients’ odds of healthy aging. Episode resource links: Shi H, Hu FB, Huang T, Schernhammer ES, Willett WC, Sun Q, Wang M. Sedentary Behaviors, Light-Intensity Physical Activity, and Healthy Aging. JAMA Netw Open. 2024 Jun 3;7(6):e2416300. doi: 10.1001/jamanetworkopen.2024.16300. PMID: 38861256; PMCID: PMC11167497. Guest: Jillian Joseph, MPAS, PA-C Music Credit: Richard Onorato Thoughts? Suggestions? Email us at [email protected] 

Credits: 0.25 AMA PRA Category 1 Credit™   CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-393 Overview: Adolescents seeking hormonal treatment for gender incongruence has become more common. A recent systematic review looking at the benefits and side effects found in clinical studies updates our current understanding of this approach. Gain insights and confidence to make informed and compassionate care decisions. Episode resource links: Taylor J, Mitchell A, Hall R, Langton T, Fraser L, Hewitt CE. Masculinising and feminising hormone interventions for adolescents experiencing gender dysphoria or incongruence: a systematic review. Arch Dis Child. 2024 Apr 9:archdischild-2023-326670. Coleman E, et al. Standards of Care for the Health of Transgender and Gender Diverse People, Version 8. Int J Transgend Health. 2022 Sep 6;23(Suppl 1):S1-S259.  Gender Affirming Hormonal Care for the Primary Care Provider Thriving for Transgender Youth Update on Trans-Competent Primary Care Guest: Alan M. Ehrlich, MD, FAAFP Thoughts? Suggestions? Email us at [email protected]  Music Credit: Richard Onorato

Credits: 0.25 AMA PRA Category 1 Credit™   CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-392 Overview: Tune in as we explore a recent study that found no net all-cause benefit or harm from vitamin D and calcium supplementation. We review the study’s findings in detail and reflect on whether these supplements should be recommended to our patients based on the latest evidence. Episode resource links: Ann Intern Med. doi:10.7326/M23-2598 Guest: Robert A. Baldor MD, FAAFP Music Credit: Richard Onorato Thoughts? Suggestions? Email us at [email protected] 

Credits: 0.25 AMA PRA Category 1 Credit™   CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-391 Overview: Cough is a frustrating complaint for patients and often leads to a prescription for antibiotics. Discover new data that reveals the ineffectiveness of antibiotics in treating acute bronchitis. Come away with valuable insights to enhance your practice and make informed treatment decisions, improving patient care and outcomes. Episode resource links: Merenstein DJ, Barrett B, Ebell MH. Antibiotics Not Associated with Shorter Duration or Reduced Severity of Acute Lower Respiratory Tract Infection. J Gen Intern Med. Published online April 15, 2024. doi:10.1007/s11606-024-08758-y Guest: Alan M. Ehrlich, MD, FAAFP   Music Credit: Richard Onorato Thoughts? Suggestions? Email us at [email protected] 

Credits: 0.25 AMA PRA Category 1 Credit™   CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-390 Overview: In 1995, the US launched a varicella vaccination program, leading to a significant drop in cases. However, breakthrough infections still occur, and clinical diagnosis has become less reliable as the virus has evolved. Join us to hear current recommendations for what to consider in the differential diagnosis and how emerging evidence may impact public health and your practice. Episode resource links: Marin, M, Leung, J, Anderson, TC, Lopez, AS. Monitoring Varicella Vaccine Impact on Varicella Incidence in the United States: Surveillance Challenges and Changing Epidemiology, 1995–2019, The Journal of Infectious Diseases, Volume 226, Issue Supplement_4, 1 November 2022, Pages S392–S399, https://doi.org/10.1093/infdis/jiac221 Qiu L, Liu S, Zhang M, et al. The epidemiology of varicella and effectiveness of varicella vaccine in Ganyu, China: a long-term community surveillance study. BMC Public Health. 2023;23(1):1875. Published 2023 Sep 28. doi:10.1186/s12889-023-16304-4 Ruprecht A, Marin M, Strain AK, Harry K, Kenyon C. Notes from the Field: Expanded Laboratory Testing for Varicella — Minnesota, 2016–2023. MMWR Morb Mortal Wkly Rep 2024;73:245–246. DOI: http://dx.doi.org/10.15585/mmwr.mm7311a3 DynaMed – Chicken pox – Varicella (https://www-dynamed-com.umassmed.idm.oclc.org/condition/chickenpox#GUID-DFBFAA99-31E8-4553-AFDB-AA1988B1967A): Guest: Susan Feeney, DNP, FNP-BC, NP-C   Music Credit: Richard Onorato

Credits: 0.25 AMA PRA Category 1 Credit™   CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-389 Overview: Let’s talk lipid panels and their potential to assess more than cardiovascular disease risk. Through a case scenario, we highlight a study on the potential link between metabolic markers and mood disorders such as depression and anxiety. Join us to learn how lipid panels could aid in early detection and intervention for these conditions. Episode resource links: Chourpiliadis C, Zeng Y, Lovik A, Wei D, Valdimarsdóttir U, Song H, Hammar N, Fang F. Metabolic Profile and Long-Term Risk of Depression, Anxiety, and Stress-Related Disorders. JAMA Netw Open. 2024 Apr 1;7(4):e244525. doi: 10.1001/jamanetworkopen.2024.4525. PMID: 38564219; PMCID: PMC10988352. Guest: Jillian Joseph, MPAS, PA-C   Music Credit: Richard Onorato

Credits: 0.25 AMA PRA Category 1 Credit™   CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-388 Overview: Tune in as expert faculty cover common upper respiratory infections in children and their treatment options, with a focus on achieving the best outcome while also lowering the risk of subsequent adverse events. Hear guideline recommendations and evidence on treatment durations to confidently make informed clinical decisions. Episode resource links: Journal of the Pediatric Infectious Diseases Society, piae034, https://doi.org/10.1093/jpids/piae034 Guest: Jillian Joseph, MPAS, PA-C   Music Credit: Richard Onorato

Credits: 0.25 AMA PRA Category 1 Credit™   CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-387 Overview: Measles incidence in the US was low, with the CDC issuing it “elimination status.” In 2024, a cluster of measles cases threatened this status. Join us while we discuss this phenomenon and its impact on public health and practice, including who is at risk, how to recognize measles, and ways to manage this contagious and vaccine-preventable illness. Episode resource links: Centers for Disease Control and Prevention (CDC): Measles Cases and Outbreaks. https://www.cdc.gov/measles/cases-outbreaks.html Center for Infectious Disease Research and Policy (CIDRAP); University of Minnesota. https://www.cidrap.umn.edu/measles/us-measles-cases-top-120-la-county-tracks-case-multiple-exposures Center for Infectious Disease Research and Policy (CIDRAP); University of Minnesota. CDC: Spike in measles cases poses threat to US elimination status. https://www.cidrap.umn.edu/measles/cdc-spike-measles-cases-poses-threat-us-elimination-status DynaMed – Measles  Guest: Susan Feeney, DNP, FNP-BC, NP-C   Music Credit: Richard Onorato

Credits: 0.25 AMA PRA Category 1 Credit™   CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-386 Overview: Physical activity can be a key component of treating depression. In this episode, we discuss the powerful impact of exercise as a nonpharmacologic option, with a spotlight on the benefits of dance. Gain strategies to guide patients on depression therapies and discover why dance stands out among forms of exercise. Episode resource links: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10870815/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10813489/ Guest: Alan M. Ehrlich, MD, FAAFP   Music Credit: Richard Onorato

Credits: 0.25 AMA PRA Category 1 Credit™   CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-385 Overview: Through the framework of a case-based scenario, this episode explores both pharmacological and surgical treatment options for obesity. We discuss the efficacy and cost challenges of injectable medications, insurance coverage, and alternative payment solutions. Gain valuable insights into the cost-effectiveness of treatments, including recent research on endoscopic sleeve gastroplasty, to better advise patients. Episode resource links: Haseeb M, Chhatwal J, Xiao J, Jirapinyo P, Thompson CC. Semaglutide vs Endoscopic Sleeve Gastroplasty for Weight Loss. JAMA Netw Open. 2024;7(4):e246221. doi:10.1001/jamanetworkopen.2024.6221 https://obesitymedicine.org/blog/does-insurance-cover-weight-loss-medication/ Guest: Jillian Joseph, PA-C   Music Credit: Richard Onorato

Credits: 0.25 AMA PRA Category 1 Credit™   CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-384 Overview: This episode investigates the inaccurate correlation made between acetaminophen use during pregnancy and an increased risk of developmental disorders, including autism spectrum disorder, in children. Expert faculty discuss the history of these claims, followed by a study evaluating outcomes in children, and emphasize the importance of evidence-based decision-making for patients and clinicians. Episode resource links: Ahlqvist VH, Sjöqvist H, Dalman C, et al. Acetaminophen Use During Pregnancy and Children’s Risk of Autism, ADHD, and Intellectual Disability. JAMA. 2024;331(14):1205–1214. doi:10.1001/jama.2024.3172 Nat Rev Endocrinol. 2021 Dec;17(12):757-766. doi: 10.1038/s41574-021-00553-7 Guest: Aylin Madore, MD, MEd   Music Credit: Richard Onorato

Credits: 0.25 AMA PRA Category 1 Credit™   CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-383 Overview: This episode highlights a growing concern—the prevalence of food allergies is on the rise. We underscore the importance for clinicians to help keep vulnerable populations safe through risk reduction strategies as well as the use of medication therapy. Feel empowered to prepare and safeguard patients from adverse reactions to food allergies. Episode resource links: Abrams, E. M., & Becker, A. B. (2015). Food introduction and allergy prevention in infants. CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne, 187(17), 1297–1301. https://doi.org/10.1503/cmaj.150364 Elghoudi, A., & Narchi, H. (2022). Food allergy in children-the current status and the way forward. World journal of clinical pediatrics, 11(3), 253–269. https://doi.org/10.5409/wjcp.v11.i3.253 Wood, R. A., Togias, A., Sicherer, S. H., Shreffler, W. G., Kim, E. H., Jones, S. M., ... & Chinthrajah, R. S. (2024). Omalizumab for the Treatment of Multiple Food Allergies. New England Journal of Medicine. https://www.foodallergy.org/living-food-allergies/food-allergy-essentials/food-allergy-anaphylaxis-emergency-care-plan CDC.gov https://acaai.org/ Guest: Mariyan L. Montaque, DNP, FNP-BC   Music Credit: Richard Onorato

Credits: 0.25 AMA PRA Category 1 Credit™   CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-382 Overview: Tune in as we discuss the AHA’s newly validated risk calculator designed to assess the risk of developing cardiovascular disease and heart failure in certain patients. We review which risk factor variables were included in the development of this new tool and whether to consider incorporating it in your practice. Episode resource links: https://doi.org/10.1161/CIRCULATIONAHA.123.067626 The calculator: https://professional.heart.org/en/guidelines-and-statements/prevent-calculator Guest: Robert A. Baldor MD, FAAFP   Music Credit: Richard Onorato

Credits: 0.25 AMA PRA Category 1 Credit™   CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-381 Overview: While the aerosol in e-cigarettes does contain toxicants and carcinogens, since it is not burned like combustible tobacco cigarettes, vaping exposes the user to fewer toxicants and chemicals. Many consider using e-cigarettes for smoking cessation, but evidence has been conflicting. Tune in as we discuss a recent review examining the efficacy of e-cigarettes in aiding smoking cessation and explore potential adverse effects associated with their usage. Episode resource links: Lin, H. X., Liu, Z., Hajek, P., Zhang, W. T., Wu, Y., Zhu, B. C., Liu, H. H., Xiang, Q., Zhang, Y., Li, S. B., Pesola, F., & Wang, Y. Y. (2024). Efficacy of Electronic Cigarettes vs Varenicline and Nicotine Chewing Gum as an Aid to Stop Smoking: A Randomized Clinical Trial. JAMA internal medicine, 10.1001/jamainternmed.2023.7846. Advance online publication. https://doi.org/10.1001/jamainternmed.2023.7846 Lindson, N., Butler, A. R., McRobbie, H., Bullen, C., Hajek, P., Begh, R., Theodoulou, A., Notley, C., Rigotti, N. A., Turner, T., Livingstone-Banks, J., Morris, T., & Hartmann-Boyce, J. (2024). Electronic cigarettes for smoking cessation. The Cochrane database of systematic reviews, 1(1), CD010216. https://doi.org/10.1002/14651858.CD010216.pub8 Sanford BT, Brownstein NC, Baker NL, et al. Shift From Smoking Cigarettes to Vaping Nicotine in Young Adults. JAMA Intern Med. Published online November 13, 2023. doi:10.1001/jamainternmed.2023.5239 Guest: Susan Feeney, DNP, FNP-BC, NP-C   Music Credit: Richard Onorato

Credits: 0.25 AMA PRA Category 1 Credit™   CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-380 Overview: This episode brings you a comparison of thiazide diuretics, angiotensin-converting enzyme (ACE) inhibitors, and calcium channel blockers on cardiovascular outcomes, stroke, and all-cause mortality. Gain evidence-based insights to help you make informed choices for your patients’ care. Episode resource links: https://pubmed.ncbi.nlm.nih.gov/38048133/#:~:text=JAMA%20Netw%20Open,10.1001/jamanetworkopen.2023.44998 Guest: Jillian Joseph, MPAS, PA-C   Music Credit: Richard Onorato

Credits: 0.25 AMA PRA Category 1 Credit™   CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-379 Overview: Recent data has shown that colchicine can improve outcomes in patients with known coronary artery disease (CAD), with consideration of colchicine now recommended by the American Heart Association (AHA). Hear valuable insights into the potential benefits and limitations to refine your clinical approach to managing CAD. Episode resource links: Nidorf SM, Fiolet ATL, Mosterd A, et al. Colchicine in Patients with Chronic Coronary Disease. N Engl J Med. 2020;383(19):1838-1847.  Mohammadnia N, Los J, Opstal TSJ, et al. Colchicine and diabetes in patients with chronic coronary artery disease: insights from the LoDoCo2 randomized controlled trial. Front Cardiovasc Med. 2023;10:1244529. Published 2023 Oct 6.  Roubille F, Bouabdallaoui N, Kouz S, et al. Low-Dose Colchicine in Patients With Type 2 Diabetes and Recent Myocardial Infarction in the COLchicine Cardiovascular Outcomes Trial (COLCOT). Diabetes Care. Published online January 5, 2024.  Guest: Alan M. Ehrlich, MD, FAAFP   Music Credit: Richard Onorato

Credits: 0.25 AMA PRA Category 1 Credit™   CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-378 Overview: Effective treatments for dementia remain elusive. In this episode, we’re discussing dementia treatment developments gathered from recent publications, covering topics of drugs, exercise, and liver disease. Stay informed and equipped to offer the latest guidance to patients with dementia and their families. Episode resource links: Ann Fam Med 2024;22:50-58. https://doi.org/10.1370/afm.3050 JAMA Netw Open. 2024;7(1):e2353965. doi:10.1001/jamanetworkopen.2023.53965 Guest: Robert A. Baldor, MD, FAAFP   Music Credit: Richard Onorato

Credits: 0.25 AMA PRA Category 1 Credit™   CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-377 Overview: Fluid in the middle ear, or otitis media with effusion (OME), is common in children with upper respiratory infections and typically resolves without treatment. Most guidelines do not recommend antibiotics for treatment; however, they are often prescribed, and the persistence of effusion can cause a significant impact on quality of life. Join us as we discuss recent review findings on antibiotics in OME treatment and the potential impact on your practice. Episode resource links: Mulvaney CA, Galbraith K, Webster KE, et al. Antibiotics for otitis media with effusion (OME) in children. Cochrane Database Syst Rev. 2023;10(10):CD015254. Published 2023 Oct 23. doi:10.1002/14651858.CD015254.pub2 Rosenfeld, R. M., Shin, J. J., Schwartz, S. R., Coggins, R., Gagnon, L., Hackell, J. M., Hoelting, D., Hunter, L. L., Kummer, A. W., Payne, S. C., Poe, D. S., Veling, M., Vila, P. M., Walsh, S. A., & Corrigan, M. D. (2016). Clinical Practice Guideline: Otitis Media with Effusion (Update). Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery, 154(1 Suppl), S1–S41. https://doi.org/10.1177/0194599815623467 Guest: Susan Feeney, DNP, FNP-BC, NP-C   Music Credit: Richard Onorato

Credits: 0.25 AMA PRA Category 1 Credit™   CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-376 Overview: While GLP-1 agents are center stage in the medical and lay press, drugs in the class of sodium-glucose cotransporter 2 inhibitors (SGLT2is) are also quite remarkable at improving a variety of health endpoints. This episode provides an overview of studies supporting the use of SGLT2is to improve patient outcomes. Episode resource links: DM/HF:  Age Ageing 2024 Jan 2;53(1):afad254. doi: 10.1093/ageing/afad254 Kidney stones: JAMA Intern Med. 2024 Jan 29:e237660. doi: 10.1001/jamainternmed.2023.7660 Guest: Susan Feeney, DNP, FNP-BC, NP-C   Music Credit: Richard Onorato

Credits: 0.25 AMA PRA Category 1 Credit™   CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-375 Overview: Listen in as we discuss trends seen in breast cancer incidence over recent decades. Despite a notable rise in its prevalence, we’ve witnessed a decline in mortality rates. This positive shift owes itself to improvements in medication and screening efforts. Explore with us the multifaceted factors shaping this evolving landscape of breast cancer diagnosis and treatment. Episode resource links: https://www.cancer.org/cancer/types/breast-cancer/about/how-common-is-breast-cancer.html https://www.uspreventiveservicestaskforce.org/uspstf/ Caswell-Jin, J. L., Sun, L. P., Munoz, D., Lu, Y., Li, Y., Huang, H., ... & Plevritis, S. K. (2024). Analysis of Breast Cancer Mortality in the US—1975 to 2019. JAMA, 331(3), 233-241. Xu, S., Murtagh, S., Han, Y., Wan, F., & Toriola, A. T. (2024). Breast Cancer Incidence Among US Women Aged 20 to 49 Years by Race, Stage, and Hormone Receptor Status. JAMA Network Open, 7(1), e2353331-e2353331. Guest: Mariyan L. Montaque, DNP, FNP-BC   Music Credit: Richard Onorato

Credits: 0.25 AMA PRA Category 1 Credit™   CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-374 Overview: This episode explores the use of data from smartphone recordings as a diagnostic tool for obstructive sleep apnea (OSA), highlighting at-home testing as a more accessible, convenient, and appropriate option for some patients. Hear how the evidence can inform your practice and improve the diagnosis and treatment of patients with OSA. Episode resource links: Han SC, Kim D, Rhee CS, Cho SW, Le VL, Cho ES, Kim H, Yoon IY, Jang H, Hong J, Lee D, Kim JW. In-Home Smartphone-Based Prediction of Obstructive Sleep Apnea in Conjunction With Level 2 Home Polysomnography. JAMA Otolaryngol Head Neck Surg. 2024 Jan 1;150(1):22-29. doi: 10.1001/jamaoto.2023.3490. PMID: 37971771; PMCID: PMC10654929. OSA and CV disease in adults, UpToDate Home sleep apnea testing for adults, UpToDate Guest: Jillian Joseph, MPAS, PA-C   Music Credit: Richard Onorato

Credits: 0.25 AMA PRA Category 1 Credit™   CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-373 Overview: In this episode, we review the effectiveness of intensive lifestyle intervention for type 2 diabetes mellitus (T2DM) remission. We unpack study findings on total diet replacement and consider its potential for improving weight loss and maintenance in patients. Tune in to enrich your clinical toolkit, empowering you to optimize patient outcomes and enhance quality of life. Episode resource links: Hocking, S. L., Markovic, T. P., Lee, C. M. Y., Picone, T. J., Gudorf, K. E., & Colagiuri, S. (2024). Intensive Lifestyle Intervention for Remission of Early Type 2 Diabetes in Primary Care in Australia: DiRECT-Aus. Diabetes care, 47(1), 66–70. https://doi.org/10.2337/dc23-0781   Centers for Disease Control:  Diabetes Care for Providers: https://www.cdc.gov/diabetes/professional-info/index.html   Optifast USA: https://www.optifast.com/   Pattinson, A. L., Seimon, R. V., Harper, C., Nassar, N., Grech, A., Santoso, E. A., Franklin, J., Inan-Eroglu, E., Gibson, A. A., & Sainsbury, A. (2021). Diet Quality following Total Meal Replacement Compared with Food-Based Weight-Loss Diets in Postmenopausal Women with Obesity: A Secondary Analysis of the TEMPO Diet Trial. The Journal of nutrition, 151(11), 3299–3312. https://doi.org/10.1093/jn/nxab311 Guest: Jill M. Terrien, PhD, ANP-BC    Music Credit: Richard Onorato

Credits: 0.25 AMA PRA Category 1 Credit™   CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-372 Overview: Listen in as we unwrap Consumer Reports’ findings on heavy metals found in commonly consumed chocolate products. Our discussion looks into concerns about high levels of metals like lead and cadmium in these treats and offers advice on how to counsel your patients for worry-free chocolate enjoyment.  Episode resource links: A Third of Chocolate Products Are High in Heavy Metals, CR T - Consumer Reports Guest: Robert A. Baldor, MD, FAAFP   Music Credit: Richard Onorato

Credits: 0.25 AMA PRA Category 1 Credit™   CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-371 Overview: Beta-blockers have traditionally been used indefinitely after a myocardial infarction (MI), but this is now only recommended for a subset of patients. Listen in as faculty review new recommendations for managing patients with chronic cardiac disease, including how to determine which patients are good candidates for beta-blocker therapy and for how long. Episode resource links: Virani SS, Newby LK, Arnold SV, et al. 2023 AHA/ACC/ACCP/ASPC/NLA/PCNA Guideline for the Management of Patients With Chronic Coronary Disease: A Report of the American Heart Association/American College of Cardiology Joint Committee on Clinical Practice Guidelines [published correction appears in Circulation. 2023 Sep 26;148(13):e148] [published correction appears in Circulation. 2023 Dec 5;148(23):e186]. Circulation. 2023;148(9):e9-e119.  Joo SJ. Beta-blocker therapy in patients with acute myocardial infarction: not all patients need it. Acute Crit Care. 2023;38(3):251-260.  Guest: Alan M. Ehrlich, MD, FAAFP   Music Credit: Richard Onorato

Credits: 0.25 AMA PRA Category 1 Credit™   CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-370 Overview: Low back pain is one of the most common symptoms presenting in primary care. Listen in as we analyze the results of a recent systematic review supporting the use of a variety of effective nonnarcotic treatments for this condition. Gain evidence-based insights to help you choose the most informed option for managing low back pain. Episode resource links: Gianola S, Bargeri S, Del Castillo G, et al. Br J Sports Med 2022;56:41–50. doi.org/ 10. 1136/ bjsports- 2020- 103596). Guest: Robert A. Baldor, MD, FAAFP   Music Credit: Richard Onorato

Credits: 0.25 AMA PRA Category 1 Credit™   CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-369 Overview: Uncover a simple, 10-second intervention—the 1-legged stance test—for predicting the risk of falling in adults. Join us as we discuss how this swift assessment can help identify patients who are prone to falls, fractures, and increased mortality. This episode brings you a practical tool to enhance patient assessments and tailor interventions, contributing to a more proactive and personalized approach to care. Episode resource links: JAMA. 2023;329(18):1605-1607. doi:10.1001/jama.2023.3054 Br J Sports Med. 2022;56:975–980. Pharmacoepidemiol Drug Saf. 2021 Aug;30(8):1049-1056. doi: 10.1002/pds.5201 PLoS Med 18(11): e1003821. https://doi.org/10.1371/journal.pmed.1003821 Guest: Jillian Joseph, MPAS, PA-C   Music Credit: Richard Onorato

Credits: 0.25 AMA PRA Category 1 Credit™   CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-368 Overview: In this insightful episode, we explore compelling data comparing inappropriate prescribing practices among physicians and nonphysician prescribers. This discussion covers the nuances and restrictive scope of prescribing authority and aims to take an evidence-based approach to encouraging collaboration between clinicians and expanding patients’ access to care. Episode resource links: Huynh, J., Alim, S. A., Chan, D. C., & Studdert, D. M. (2023). Inappropriate Prescribing to Older Patients by Nurse Practitioners and Primary Care Physicians. Annals of internal medicine, 176(11), 1448–1455. https://doi.org/10.7326/M23-0827 American Association of Nurse Practitioners https://www.aanp.org/ American Academy of Physician Associates https://www.aapa.org/ Jiao, S., Murimi, I. B., Stafford, R. S., Mojtabai, R., & Alexander, G. C. (2018). Quality of Prescribing by Physicians, Nurse Practitioners, and Physician Assistants in the United States. Pharmacotherapy, 38(4), 417–427. https://doi.org/10.1002/phar.2095 2023 Beers Criteria American Geriatrics Society: Free to read https://agsjournals.onlinelibrary.wiley.com/doi/epdf/10.1111/jgs.18372 Guest: Jill M. Terrien PhD, ANP-BC    Music Credit: Richard Onorato

Credits: 0.25 AMA PRA Category 1 Credit™   CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-367 Overview: Join us for a look at the Portfolio Diet, a plant-based approach with potential to improve cardiovascular outcomes. We’ll take you through the details of this regimen and what the evidence says about its effect on the risks of cardiovascular diseases. Stay informed on the latest research and feel prepared to answer your patients’ questions about the Portfolio Diet. Episode resource links: Circulation. 2023;148:00–00. DOI: 10.1161/CIRCULATIONAHA.123.065551 Guest: Robert A. Baldor, MD, FAAFP   Music Credit: Richard Onorato

Credits: 0.25 AMA PRA Category 1 Credit™   CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-366 Overview: Join us as we explore the nuances of healthy eating patterns, distinguishing between time-restricted and calorie-restricted approaches. We also review a randomized controlled trial that found time-restricted eating for people with type 2 diabetes mellitus (T2DM) can benefit HbA1c levels and weight reduction. Gain insights to elevate patient care in understanding and implementing these impactful dietary strategies. Episode resource links: Pavlou V, Cienfuegos S, Lin S, et al. Effect of Time-Restricted Eating on Weight Loss in Adults With Type 2 Diabetes: A Randomized Clinical Trial. JAMA Netw Open. 2023;6(10):e2339337. doi:10.1001/jamanetworkopen.2023.39337 Jefcoate PW, Robertson MD, Ogden J, Johnston JD. Exploring Rates of Adherence and Barriers to Time-Restricted Eating. Nutrients. 2023 May 16;15(10):2336. doi: 10.3390/nu15102336. PMID: 37242218; PMCID: PMC10223820. Guest: Jillian Joseph, MPAS, PA-C   Music Credit: Richard Onorato

Credits: 0.25 AMA PRA Category 1 Credit™   CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-365 Overview: The chronic nature of irritable bowel syndrome (IBS) necessitates persistence when trialing treatment options. After reviewing key identifiers of IBS, we discuss a second-line treatment’s efficacy in reducing symptoms and improving quality of life for patients with continued IBS symptoms. Tune in for valuable insights to make informed recommendations for your patients. Episode resource links: Amitriptyline at Low-Dose and Titrated for Irritable Bowel Syndrome as Second-Line Treatment in primary care (ATLANTIS): a randomised, double-blind, placebo-controlled, phase 3 trial - PubMed (nih.gov) https://www.aafp.org/pubs/afp/issues/2005/1215/p2501.html Guest: Mariyan L. Montaque, DNP, FNP-BC   Music Credit: Richard Onorato

Credits: 0.25 AMA PRA Category 1 Credit™   CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-364 Overview: In this episode, we explore a nonpharmacologic approach to easing symptoms of COVID-19 in patients who are at lower risk of progression. Supported by a small study, a nasal saline rinse and gargle regimen was associated with more rapid symptom resolution and lower hospitalization rates. Learn how a simple salt solution can be an effective step in preventing adverse outcomes of COVID-19 for patients who are at low risk. Episode resource links: Am Col Allergy Asthma and Immunology: https://acaai.org/news/new-study-gargling-with-salt-water-may-help-prevent-covid-hospitalization/ Guest: Jillian Joseph, MPAS, PA-C   Music Credit: Richard Onorato

Credits: 0.25 AMA PRA Category 1 Credit™   CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-363 Overview: Patients often reach for vitamins and supplements in type 2 diabetes mellitus (T2DM) management, but what does the research show? In this episode, you’ll hear expert faculty discuss the efficacy of vitamins and supplements, debunk common myths, and explore the power of dietary changes and exercise. Deepen your knowledge to guide your patients toward taking evidence-based steps in their T2DM management. Episode resource links: Cinnamon J Pharmacy Practice. 2017;30(6):631-638. J Med Food . 2011 Sep;14(9):884-9. doi: 10.1089/jmf.2010.0180 J Endocr Soc. 2020 Nov 1; 4(11): bvaa094 Chromium Biol Trace Elem Res. 2022 Feb;200(2):516-525.  Vitamin C Diabetes Metab Syndr. 2023 Jul 7;17(8):102824. Vitamin D Ann Intern Med. 2023 Mar;176(3):355-363. doi: 10.7326/M22-301 Soluble Fiber:   Diabetes Care. 2019 Jan 7. pii: dc181126. doi: 10.2337/dc18-1126 Guest: Jillian Joseph, MPAS, PA-C   Music Credit: Richard Onorato

Credits: 0.25 AMA PRA Category 1 Credit™   CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-362 Overview: Recorded live at Pri-Med East! Iron deficiency and IDA are common, especially in women of childbearing age, and often under diagnosed. These conditions carry with them risk for increased morbidity and mortality. Screening is focused on high-risk groups, specifically toddlers and pregnant women, however these conditions in women of childbearing age are also common. Please join us to discuss the recent data on the prevalence of ID/IDA, how to appropriately screen and treat this common condition.  Episode resource links: Weyand AC, Chaitoff A, Freed GL, Sholzberg M, Choi SW, McGann PT. Prevalence of Iron Deficiency and Iron-Deficiency Anemia in US Females Aged 12-21 Years, 2003-2020. JAMA. 2023;329(24):2191-2193. doi:10.1001/jama.2023.8020 Dyna-Med: https://www-dynamed-com.umassmed.idm.oclc.org/management/treatment-of-iron-deficiency-anemia-in-adults#IRON_DEFICIENCY_WITHOUT_ANEMIA   NIH Iron Fact Sheet for Health Professionals: https://ods-od-nih-gov.umassmed.idm.oclc.org/factsheets/Iron-HealthProfessional/ Guest: Susan Feeney, DNP, FNP-BC, NP-C   Music Credit: Richard Onorato

Credits: 0.25 AMA PRA Category 1 Credit™   CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-361 Overview: In this episode, we delve into a topic of growing interest in medicine—the use of psilocybin to treat depression. Join us as we discuss the pharmacotherapeutic action of psilocybin and the results of a recent study that has suggested that a one-time dose of psilocybin can be an effective treatment for depression. Hear valuable insights into the potential benefits and limitations and feel prepared to respond to patient questions about this treatment. Episode resource links: JAMA. 2023;330(9):843-853. doi:10.1001/jama.2023.14530 Guest: Robert A. Baldor MD, FAAFP   Music Credit: Richard Onorato

Credits: 0.25 AMA PRA Category 1 Credit™   CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-360 Overview: Join us as we examine common medical myths encountered in primary care. Hear what the evidence has to say about grapefruit and statins, vitamin K-rich vegetables and warfarin, and biotin for treating hair loss. Stay informed, challenge assumptions, and enhance your practice with insights on these long-held beliefs. Episode resource links: Grapefruit: Am J Med 2016; Vol 129 (1): 26-29, Br J Clin Pharmacol. 2011 Sep;72(3):434-41.   Warfarin: Medicine (Baltimore). 2016 Mar;95(10):e2895   Biotin: The Journal of Clinical and Aesthetic Dermatology. 2020;13(3):37-40 Guest: Jillian Joseph, MPAS, PA-C, Susan Feeney, DNP, FNP-BC, NP-C   Music Credit: Richard Onorato

Credits: 0.25 AMA PRA Category 1 Credit™   CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-359 Overview: There is plenty of evidence linking exercise to improved overall health. It is associated with weight loss, improved biomarkers, improved sleep, and mood. The few studies comparing types and intensity of exercise have resulted in varied and inconsistent findings. Listen in as we discuss a recent prospective cohort study examining associations between combinations of exercise and reduction in all-cause, cardiovascular, and cancer mortality and how the evidence can inform your practice to improve patients’ health. Episode resource links: López-Bueno, R., Ahmadi, M., Stamatakis, E., Yang, L., & Del Pozo Cruz, B. (2023). Prospective Associations of Different Combinations of Aerobic and Muscle-Strengthening Activity With All-Cause, Cardiovascular, and Cancer Mortality. JAMA internal medicine, 183(9), 982–990. https://doi.org/10.1001/jamainternmed.2023.3093   Standards of Care, 2023 American Diabetic Association. https://diabetesjournals.org/care/issue/46/Supplement_1   https://www.heart.org/en/healthy-living/fitness/fitness-basics/aha-recs-for-physical-activity-in-adults   https://diabetes.org/health-wellness/fitness Guest: Susan Feeney, DNP, FNP-BC, NP-C   Music Credit: Richard Onorato

Credits: 0.25 AMA PRA Category 1 Credit™   CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-358 Overview: In this episode, we explore new data that could reshape how we approach sexually transmitted infection (STI) prevention in clinical practice. Discover how doxycycline can serve as prophylaxis for bacterial STIs in populations who are at high risk and come away with practical strategies for counseling patients on STI prevention. Tune in to enhance your clinical expertise and provide superior care to your patients. Episode resource links: Luetkemeyer AF, Donnell D, Dombrowski JC, et al. Postexposure Doxycycline to Prevent Bacterial Sexually Transmitted Infections. N Engl J Med. 2023;388(14):1296-1306.  Guest: Alan M. Ehrlich MD, FAAFP   Music Credit: Richard Onorato

Credits: 0.25 AMA PRA Category 1 Credit™   CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-357 Overview: Progesterone-based emergency contraception (EC) is established as a method to reduce the risk of pregnancy after unprotected intercourse. This EC works by blocking or delaying ovulation. However, if taken after ovulation, there is a higher failure rate. A recent study showed increased efficacy of levonorgestrel when given with a COX-2 inhibitor (NSAID). Please join us as we discuss the results of the randomized controlled trial, including the efficacy of levonorgestrel when taken with piroxicam and their potential to reduce EC failure. Episode resource links: Li, R. H. W., Lo, S. S. T., Gemzell-Danielsson, K., Fong, C. H. Y., Ho, P. C., & Ng, E. H. Y. (2023). Oral emergency contraception with levonorgestrel plus piroxicam: a randomised double-blind placebo-controlled trial. Lancet (London, England), 402(10405), 851–858. https://doi.org/10.1016/S0140-6736(23)01240-0 Guest: Susan Feeney, DNP, FNP-BC, NP-C   Music Credit: Richard Onorato

Credits: 0.25 AMA PRA Category 1 Credit™   CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-356 Overview: Patient-reported penicillin allergies are common; however, more than 95% of such patients have negative penicillin allergy testing and will tolerate subsequent antibiotic use. Currently, disproving a penicillin allergy includes negative skin testing followed by an oral challenge, which is considered the gold standard to remove the penicillin allergy label, as skin testing alone lacks 100% negative predictive value. Recent reports have suggested that low-risk individuals can be assessed with a direct oral challenge, but the safety and efficacy of such an approach has not been rigorously studied. Listen in as expert faculty discuss a recent randomized controlled trial that validates such an approach. Episode resource links: Trubiano JA, Vogrin S, Chua KYL et al. Development and Validation of a Penicillin Allergy Clinical Decision Rule. JAMA Internal Med. Published March 16, 2020. doi:10.1001/jamainternmed.2020.0403 JAMA Intern Med. doi:10.1001/jamainternmed.2023.2986 Guest: Robert A. Baldor MD, FAAFP   Music Credit: Richard Onorato

Credits: 0.25 AMA PRA Category 1 Credit™   CME/CE Information and Claim Credit: https://www.pri-med.com/online-cme-ce/podcast/frankly-speaking-cme-ep-355 Overview: Discover how primary care providers can actively combat dementia risk in aging patients. In this episode, expert faculty explore recent studies revealing the benefits of dementia prevention and evidence-based activities for reducing risks. Learn how to provide encouragement and social activity prescriptions during visits, and gain essential knowledge to preserve cognitive function, ultimately improving patient care and quality of life. Episode resource links: Cho, G., Betensky, R. A., & Chang, V. W. (2023). Internet usage and the prospective risk of dementia: A population-based cohort study. Journal of the American Geriatrics Society, 71(8), 2419–2429. https://doi.org/10.1111/jgs.18394 Raichlen DA, Aslan DH, Sayre MK, et al. (2023). Sedentary Behavior and Incident Dementia Among Older Adults. JAMA. 330(10):934–940. https://doi:10.1001/jama.2023.15231 Su, S., Shi, L., Zheng, Y., Sun, Y., Huang, X., Zhang, A., Que, J., Sun, X., Shi, J., Bao, Y., Deng, J., & Lu, L. (2022). Leisure Activities and the Risk of Dementia: A Systematic Review and Meta-Analysis. Neurology, 99(15), e1651–e1663. Advance online publication. https://doi.org/10.1212/WNL.0000000000200929 Guest: Jill M. Terrien PhD, ANP-BC    Music Credit: Richard Onorato

Credits: 0.25 AMA PRA Category 1 Credit™   CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-354 Overview: There is an overlap of acute sinusitis symptoms and viral upper respiratory tract infection, such that many children are treated unnecessarily with antibiotics. In this episode, we review 2 recent studies that inform recommendations on whether or not to treat childhood sinusitis with amoxicillin/clavulanate. Gain practical strategies and the confidence to appropriately address sinusitis in the children you treat. Episode resource links: JAMA. 2023;330(4):349-358. doi:10.1001/jama.2023.10854 JAMA. 2023;330(11):1064-1073. doi:10.1001/jama.2023.15503 Journal of Pediatrics, The, 2019-04-01, Volume 207, Pages 103-108.e1 Guest: Robert A. Baldor MD, FAAFP   Music Credit: Richard Onorato

Credits: 0.25 AMA PRA Category 1 Credit™   CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-353 Overview: Bronchiolitis caused by respiratory syncytial virus (RSV) infection in infants is common and can lead to hospitalization if severe. There are now 2 ways to prevent this: immunizing the mother during pregnancy or giving monoclonal antibodies. Listen in as we discuss the recommendations for RSV prevention and how to best incorporate them into your practice. Episode resource links: Fleming-Dutra KE, Jones JM, Roper LE, et al. Use of the Pfizer Respiratory Syncytial Virus Vaccine During Pregnancy for the Prevention of Respiratory Syncytial Virus–Associated Lower Respiratory Tract Disease in Infants: Recommendations of the Advisory Committee on Immunization Practices — United States, 2023. MMWR Morb Mortal Wkly Rep 2023;72:1115–1122. Jones JM, Fleming-Dutra KE, Prill MM, et al. Use of Nirsevimab for the Prevention of Respiratory Syncytial Virus Disease Among Infants and Young Children: Recommendations of the Advisory Committee on Immunization Practices — United States, 2023. MMWR Morb Mortal Wkly Rep 2023;72:920–925 Kampmann B, Madhi SA, Munjal I, et al. Bivalent Prefusion F Vaccine in Pregnancy to Prevent RSV Illness in Infants. N Engl J Med. 2023;388(16):1451-1464. Guest: Alan M. Ehrlich MD, FAAFP   Music Credit: Richard Onorato

Credits: 0.25 AMA PRA Category 1 Credit™   CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-352 Overview: Keep your practice at the forefront of outpatient COVID-19 management with this informative episode. Listen in as expert faculty discuss the latest recommendations and review ineffective treatments, helping you provide the best care during this new phase of the endemic. Episode resource links: https://www.covid19treatmentguidelines.nih.gov/management/clinical-management-of-adults/clinical-management-of-adults-summary/?utm_source=site&utm_medium=home&utm_campaign=highlights Abdool Karim, S. S., & Devnarain, N. (2022). Time to stop using ineffective COVID-19 drugs. New England Journal of Medicine, 387(7), 654-655. Hayden, M. K., Hanson, K. E., Englund, J. A., Lee, F., Lee, M. J., Loeb, M., ... & Mustafa, R. A. (2023). The Infectious Diseases Society of America guidelines on the diagnosis of COVID-19: antigen testing. Clinical Infectious Diseases, ciad032. Guest: Mariyan L. Montaque, DNP, FNP-BC   Music Credit: Richard Onorato

Credits: 0.25 AMA PRA Category 1 Credit™   CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-351 Overview: Live at Pri-Med East! In this episode, we will examine the association of developmental delays with amount of screen time in children. Episode resource links: https://jamanetwork.com/journals/jamapediatrics/fullarticle/2808593 https://www.aap.org/en/patient-care/media-and-children/center-of-excellence-on-social-media-and-youth-mental-health/social-media-and-youth-mental-health-q-and-a-portal/middle-childhood/middle-childhood-questions/screen-time-guidelines/ https://www.aacap.org/AACAP/Families_and_Youth/Facts_for_Families/FFF-Guide/Children-And-Watching-TV-054.aspx Guest: Jillian Joseph, MSPAS, PA-C Music Credit: Richard Onorato

Credits: 0.25 AMA PRA Category 1 Credit™   CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-350 Overview: Nuts have a reputation for providing a variety of health benefits, but how far do their nutritional superpowers reach? In this episode, we take a look at the findings of a study showing the association between nut consumption and cognitive performance. Listen in as expert faculty discuss the implications for managing patients at risk for cognitive decline. Episode resource links: The American Journal of Clinical Nutrition https://doi.org/10.1016/j.ajcnut.2023.05.032 Guest: Robert A. Baldor MD, FAAFP   Music Credit: Richard Onorato

Credits: 0.25 AMA PRA Category 1 Credit™   CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-349 Overview: Recent observational data has shown the potential for bariatric surgery to lower breast cancer risk in women with obesity. Tune in as faculty discuss what the evidence says about this connection and when to consider exploring the option for your patients’ weight-loss management. Episode resource links: AMA Surg. 2023 Jun 1;158(6):634-641. doi: 10.1001/jamasurg.2023.0530. J Natl Cancer Inst. 2003;95(16):1218. J Natl Cancer Inst. 2015;107(2) Epub 2015 Mar 10.  Guest: Robert A. Baldor MD, FAAFP   Music Credit: Richard Onorato

Credits: 0.25 AMA PRA Category 1 Credit™   CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-348 Overview: Discover how wearable fitness devices are transforming early detection of atrial fibrillation with their potential to reduce stroke risk. In this episode, we share insights on leveraging smartwatches to improve health outcomes and when to encourage their use in patient care. Episode resource links: Bedi, A., Al Masri, M. K., Al Hennawi, H., Qadir, S., & Ottman, P. (2023). The Integration of Artificial Intelligence Into Patient Care: A Case of Atrial Fibrillation Caught by a Smartwatch. Cureus, 15(3). Long, K. Y., Shanmugam, K., & Rana, M. E. (2023, January). An Evaluation of Smartwatch Contribution in Improving Human Health. In 2023 17th International Conference on Ubiquitous Information Management and Communication (IMCOM) (pp. 1-4). IEEE. Mattison, G., Canfell, O. J., Forrester, D., Dobbins, C., Smith, D., Reid, D., & Sullivan, C. (2023). A step in the right direction: the potential role of smartwatches in supporting chronic disease prevention in health care. The Medical Journal of Australia, 218(9), 384-388. Meza, C., Juega, J., Francisco, J., Santos, A., Duran, L., Rodriguez, M., ... & Pagola, J. (2023). Accuracy of a Smartwatch to Assess Heart Rate Monitoring and Atrial Fibrillation in Stroke Patients. Sensors, 23(10), 4632. https://www.stroke.org/en/about-stroke/types-of-stroke/cryptogenic-stroke   Guest: Mariyan L. Montaque, DNP, FNP-BC   Music Credit: Richard Onorato

Credits: 0.25 AMA PRA Category 1 Credit™   CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-347 Overview: In this episode, we’re diving into recent research that uncovers a compelling link between obstructive sleep apnea and cognitive decline in older adults. Join expert faculty as they dissect the findings and provide invaluable insights to comprehensively address this connection in your practice. Episode resource links: Discuss recent evidence that links obstructive sleep apnea (OSA) to cognitive decline risk in older people Describe ways to incorporate this new evidence to identify OSA and reduce the risk of cognitive decline  Guest: Susan Feeney, DNP, FNP-BC, NP-C   Music Credit: Richard Onorato

Credits: 0.25 AMA PRA Category 1 Credit™   CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-346 Overview: As we encounter more patients asking about the recent FDA approval of a new respiratory syncytial virus (RSV) vaccine for older adults, it’s crucial that we keep up to date. Join us as we review the supporting studies, indications, and precautions, giving you confidence in conversations with inquiring patients.  Episode resource links: https://www.fda.gov/news-events/press-announcements/fda-approves-first-respiratory-syncytial-virus-rsv-vaccine Guest: Robert A. Baldor MD, FAAFP   Music Credit: Richard Onorato

Credits: 0.25 AMA PRA Category 1 Credit™   CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-345 Overview: In this episode, we discuss the findings of a recent Lancet publication on a novel neurokinin 3 (NK3) receptor antagonist for treating hot flashes. Tune in as we talk about how this nonhormonal treatment addresses menopausal hot flashes, the prescribing precautions issued by the FDA, and the implications for patients seeking your help with alleviating symptoms. Episode resource links: Lancet 2023; 401: 1091–102. doi.org/10.1016/ S0140-6736(23)00085-5 Am Fam Physician. 2023;108(1):28-39 Guest: Robert A. Baldor MD, FAAFP   Music Credit: Richard Onorato

Credits: 0.25 AMA PRA Category 1 Credit™   CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-344 Overview: Navigating the intricate landscape of pain management in older patients with dementia can be challenging. Join us as we explore strategies for mitigating pain, consider the equilibrium between opioid benefits and risks, and discuss where to start when tailoring management plans for patients with dementia and joint pain. Don’t miss this important conversation. Episode resource links: https://www.neurologylive.com/view/mortality-risk-significantly-increased-with-new-opioid-use-older-adults-dementia https://www.practicalpainmanagement.com/resource-centers/opioid-prescribing-monitoring/risk-assessment-safe-opioid-prescribing-tools Guest: Jillian Joseph, MPAS, PA-C   Music Credit: Richard Onorato

Credits: 0.25 AMA PRA Category 1 Credit™   CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-343 Overview: In this episode, we take a look at a study exploring the effects on children’s activity levels when their parents reduce smartphone use. Listen in as we discuss compelling findings that shed light on the connection, and come away with guidance on how to navigate the evolving digital landscape to promote healthier, more active lifestyles among children. Episode resource links: JAMA Pediatr. 2022 Aug; 176(8): 741–749 BMJ Open. 2019 Jan 3;9(1):e023191. doi: 10.1136/bmjopen-2018-023191 Guest: Robert A. Baldor MD, FAAFP   Music Credit: Richard Onorato

Credits: 0.25 AMA PRA Category 1 Credit™   CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-342 Overview: In July of 2023, the FDA made a monumental decision to approve Opill, marking the first time an oral contraceptive will be made available without a prescription. The inaugural over-the-counter oral contraceptive is a progesterone-only pill. Join us to discuss the underlying rationales driving this decision and the prospective implications it might have on medical practice as well as women’s health. Episode resource links: Biggs, AM, Ralph, L, Morris, N, Ehrenreich, K, Perritt, J, Kapp, N, Blanchard, K, White, K,  Barar, Grossman, RD. A cross-sectional survey of U.S. abortion patients’ interest in obtaining medication abortion over the counter, Contraception, Volume 109, 2022, Pages 25-31, ISSN 0010-7824, https://doi.org/10.1016/j.contraception.2022.01.010.   Chen, Q.J. Xiang, W.P. Zhang, D.K., Wang, R.P. Luo, Y.F. Kang, J.Z. Cheng, L.N. Efficacy and safety of a levonorgestrel enteric-coated tablet as an over-the-counter drug for emergency contraception: a Phase IV clinical trial, Human Reproduction, Volume 26, Issue 9, September 2011, Pages 2316–2321, https://doi.org/10.1093/humrep/der181   Raine, TR; Ricciotti, N; Sokoloff, A; Brown, B; Hummel, A; Harper, C. An Over-the-Counter Simulation Study of a Single-Tablet Emergency Contraceptive in Young Females. Obstetrics & Gynecology 119(4):p 772-779, April 2012. | DOI: 10.1097/AOG.0b013e31824c0aed   https://www.fda.gov/news-events/press-announcements/fda-approves-first-nonprescription-daily-oral-contraceptive   https://www.accessdata.fda.gov/drugsatfda_docs/nda/2023/017031Orig1s041SumR.pdf Guest: Susan Feeney, DNP, FNP-BC, NP-C   Music Credit: Richard Onorato

Credits: 0.25 AMA PRA Category 1 Credit™   CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-341 Overview: Listen in as we review a recent JAMA publication of a randomized controlled trial that quantified the benefits of a targeted approach to prescribing antihypertensive medications. Don’t miss this opportunity to keep your management of patients with hypertension up to date. Episode resource links: Sundström J, Lind L, Nawrouzi S, et al. Heterogeneity in blood pressure response to 4 antihypertensive drugs: a randomized clinical trial. JAMA. Published April 11, 2023. doi:10.1001/jama.2023.3322 Guest: Robert A. Baldor MD, FAAFP   Music Credit: Richard Onorato

Credits: 0.25 AMA PRA Category 1 Credit™   CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-340 Overview: Depression and anxiety rates are escalating, with a 36% increase in suicide cases between 2018 and 2021, as reported by the CDC. This distressing trend can be attributed to various significant stressors that have arisen in recent times, such as pandemic-related illness and isolation. Medications alone are not as effective as when other modalities are incorporated into the treatment regime. Recent meta-analysis has revealed a strong correlation between engaging in physical activity and reducing suicidal ideation across all levels. Listen in as we discuss these findings and explore practical strategies for their implementation in your clinical practice. Episode resource links: Vancampfort, D., Hallgren, M., Firth, J., Rosenbaum, S., Schuch, F. B., Mugisha, J., Probst, M., Van Damme, T., Carvalho, A. F., & Stubbs, B. (2017). Physical activity and suicidal ideation: a systematic review and meta-analysis. Journal of Affective Disorders. https://doi.org/10.1016/j.jad.2017.08.070 https://www.healio.com/news/primary-care/20230403/metaanalysis-exe Guest: Susan Feeney, DNP, FNP-BC, NP-C   Music Credit: Richard Onorato

Credits: 0.25 AMA PRA Category 1 Credit™   CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-339 Overview: In this episode, we dive into a recent systematic review and meta-analysis confirming the association between cannabidiol (CBD) use and hepatotoxicity. Gain a deeper understanding of clinical applications and the delicate balance of risks and benefits when discussing CBD use with your patients. Episode resource links: Lo LA, Christiansen A, Eadie L, Strickland JC, Kim DD, Boivin M, Barr AM, MacCallum CA. Cannabidiol-associated hepatotoxicity: A systematic review and meta-analysis. J Intern Med. 2023 Mar 13. doi: 10.1111/joim.13627. Epub ahead of print. PMID: 36912195. https://store.samhsa.gov/sites/default/files/pep22-06-04-003.pdf Guest: Jillian Joseph, MPAS, PA-C   Music Credit: Richard Onorato

Credits: 0.25 AMA PRA Category 1 Credit™   CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-338 Overview: Listen in as we explore the connection between asthma and cancer. We examine new Global Initiative for Asthma (GINA) guidelines and recent observational data correlating an asthma diagnosis with an increased cancer risk. Don't miss out on this essential discussion that will empower you with valuable knowledge for enhanced patient care. Episode resource links: Guo, Y, Bian, J, Chen, Z, et al. Cancer incidence after asthma diagnosis: Evidence from a large clinical research network in the United States. Cancer Med. 2023; 00: 1- 7. doi:10.1002/cam4.5875 GINA guidelines 2022: https://ginasthma.org/wp-content/uploads/2022/07/GINA-Main-Report-2022-FINAL-22-07-01-WMS.pdf Guest: Robert A. Baldor MD, FAAFP   Music Credit: Richard Onorato

Credits: 0.25 AMA PRA Category 1 Credit™   CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-337 Overview: There has been uncertainty as to the best time for patients to take blood pressure medications. Tune in as we review the Treatment in Morning versus Evening (TIME) study, which assessed whether morning or evening dosing improves cardiovascular outcomes. Episode resource links: Mackenzie IS, Rogers A, Poulter NR, et al. Cardiovascular outcomes in adults with hypertension with evening versus morning dosing of usual antihypertensives in the UK (TIME study): a prospective, randomised, open-label, blinded-endpoint clinical trial. Lancet. 2022;400(10361):1417-1425.  Guest: Alan M. Ehrlich MD, FAAFP   Music Credit: Richard Onorato

Credits: 0.25 AMA PRA Category 1 Credit™   CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-336 Overview: In 2020, the National Asthma Education and Prevention Program (NAEPP) updated its guidelines for asthma management, incorporating significant changes. This marked the first update since 2007. A recent study revealed that >280 providers of the new asthma guidelines had an average knowledge score of 45%, indicating that these guidelines have likely not been fully incorporated into their practice. We invite you to join us as we discuss the new guidelines and explore strategies for integrating them into your practice. Episode resource links: Cloutier MM, Dixon AE, Krishnan JA, Lemanske RF, Pace W, Schatz M. Managing Asthma in Adolescents and Adults: 2020 Asthma Guideline Update from the National Asthma Education and Prevention Program. JAMA. 2020;324(22):2301–2317. doi:10.1001/jama.2020.2197   https://jamanetwork.com/journals/jama/article-abstract/2773482 https://www.jacionline.org/programs_abstracts https://www.healio.com/news/primary-care/20230225/physicians-show-lack-of-knowledge-on-latest-updates-to-asthma-management-guidelines   Cloutier MM, Teach, SJ., Lemanske RF, Blake KV. The 2020 Focused Updates to the NIH Asthma Management Guidelines: Key Points for Pediatricians. PEDIATRICS Volume 147, number 6, June 2021:e2021050286; https://publications.aap.org/pediatrics/article/147/6/e2021050286/180305/The-2020-Focused-Updates-to-the-NIH-Asthma?autologincheck=redirected   GINA Guidelines: https://ginasthma.org/pocket-guide-for-asthma-management-and-prevention/ Pocket Guide: https://ginasthma.org/wp-content/uploads/2022/07/GINA-2022-Pocket-Guide-WMS.pdf Guest: Susan Feeney, DNP, FNP-BC, NP-C   Music Credit: Richard Onorato

Credits: 0.25 AMA PRA Category 1 Credit™   CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-335 Overview: In this episode, we review recent updates from the Diabetes Prevention Program (DPP) trial and Diabetes Prevention Program Outcomes Study (DPPOS). Join us as we discuss the impact of the updates on diabetes prevention strategies for cardiovascular outcomes. Episode resource links: Goldberg RB, Orchard TJ, Crandall JP, Boyko EJ, Budoff M, Dabelea D, Gadde KM, Knowler WC, Lee CG, Nathan DM, Watson K, Temprosa M; Diabetes Prevention Program Research Group*. Effects of Long-term Metformin and Lifestyle Interventions on Cardiovascular Events in the Diabetes Prevention Program and Its Outcome Study. Circulation. 2022 May 31;145(22):1632-1641. doi: 10.1161/CIRCULATIONAHA.121.056756. Epub 2022 May 23. PMID: 35603600; PMCID: PMC9179081. Galaviz KI, Weber MB, Suvada K BS, Gujral UP, Wei J, Merchant R, Dharanendra S, Haw JS, Narayan KMV, Ali MK. Interventions for Reversing Prediabetes: A Systematic Review and Meta-Analysis. Am J Prev Med. 2022 Apr;62(4):614-625. doi: 10.1016/j.amepre.2021.10.020. Epub 2022 Feb 10. PMID: 35151523. Guest: Jillian Joseph, MPAS, PA-C   Music Credit: Richard Onorato

Credits: 0.25 AMA PRA Category 1 Credit™   CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-334 Overview: It can be tricky to navigate conflicting data when discussing alcohol intake with patients, so we’re here to discuss the topic’s most recent evidence. In this episode, we take a look at the findings to help you and your patients make informed decisions about daily alcohol consumption and their health. Episode resource links: JAMA Network Open. 2023;6(3):e236185. doi:10.1001/jamanetworkopen.2023.6185 Guest: Robert A. Baldor MD, FAAFP   Music Credit: Richard Onorato

Credits: 0.25 AMA PRA Category 1 Credit™   CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-333 Overview: Tune in as we discuss the potential consequences of perceived stress on the cognition and well-being of older adults. We explore screening and intervention opportunities to better help you recognize and manage stress in your patients aged ≥45 years. Episode resource links: Kulshreshtha, A., Alonso, A., McClure, L. A., Hajjar, I., Manly, J. J., & Judd, S. (2023). Association of Stress With Cognitive Function Among Older Black and White US Adults. JAMA network open, 6(3), e231860. https://doi.org/10.1001/jamanetworkopen.2023.1860 Top 12 Apps for Mindfulness https://positivepsychology.com/mindfulness-apps/ 15 Simple Ways to Relieve Stress 15 Simple Ways to Relieve Stress and Anxiety (healthline.com) Guest: Jill M. Terrien PhD, ANP-BC    Music Credit: Richard Onorato

Credits: 0.25 AMA PRA Category 1 Credit™   CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-332 Overview: In this episode, we take a look at the dynamic landscape of hyperlipidemia management, discussing current guidelines for hyperlipidemia treatment and the interplay between evidence-based recommendations and expert opinions. Tune in to gain a broader understanding of hyperlipidemia management and unlock fresh perspectives to enhance patient care. Episode resource links: JAMA Intern Med. March 14, 2022. doi:10.1001/jamainternmed.2022.0134 JAMA. Published online March 6, 2023. doi:10.1001/jama.2023.2487 Guest: Robert A. Baldor MD, FAAFP   Music Credit: Richard Onorato

Credits: 0.25 AMA PRA Category 1 Credit™   CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-331 Overview: Current recommendations for when to start breast cancer screening do not consider race or ethnicity, which may be a source of racial disparity in breast cancer outcomes. In this installment, we take a closer look at these recommendations and how you can incorporate them into individualized patient care. Episode resource links: Chen T, Kharazmi E, Fallah M. Race and Ethnicity-Adjusted Age Recommendation for Initiating Breast Cancer Screening. JAMA Netw Open. 2023;6(4):e238893. Published 2023 Apr 3. Siu AL; U.S. Preventive Services Task Force. Screening for Breast Cancer: U.S. Preventive Services Task Force Recommendation Statement [published correction appears in Ann Intern Med. 2016 Mar 15;164(6):448]. Ann Intern Med. 2016;164(4):279-296 Oeffinger KC, Fontham ET, Etzioni R, et al. Breast Cancer Screening for Women at Average Risk: 2015 Guideline Update From the American Cancer Society [published correction appears in JAMA. 2016 Apr 5;315(13):1406]. JAMA. 2015;314(15):1599-1614.  Draft Update of USPSTF Screening for Breast Cancer: https://www.uspreventiveservicestaskforce.org/uspstf/draft-recommendation/breast-cancer-screening-adults Guest: Alan M. Ehrlich MD, FAAFP   Music Credit: Richard Onorato

Credits: 0.25 AMA PRA Category 1 Credit™   CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-330 Overview: The CDC’s Household Pulse Survey data indicate that more than 10% of adults who contracted COVID-19 have had symptoms that lasted at least 3 months. While patients worry about long COVID, there are no specific tests to confirm its diagnosis. In this episode, we discuss a recent JAMA article that addresses the primary care approach to long COVID. Episode resource links: Landhuis EW. How Primary Care Physicians Can Recognize and Treat Long COVID. JAMA. Published online May 03, 2023. doi:10.1001/jama.2023.6604 JAMA. 2022;328(16):1604. PMID: 36215063 Post-COVID Conditions: Information for Healthcare Providers (cdc.gov) Guest: Robert A. Baldor MD, FAAFP Music Credit: Richard Onorato

Credits: 0.25 AMA PRA Category 1 Credit™   CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-329 Overview: Do you have older patients asking for guidance on what supplements can be used to prevent cognitive decline? Listen in to hear the findings of a recent Alzheimer’s & Dementia publication of a randomized controlled trial looking at the benefits and harms related to using cocoa and multivitamins for preventing cognitive decline. Episode resource links: Baker LD,Manson JE, Rapp SR, et al. Effects of cocoa extract and a multivitamin on cognitive function: A randomized clinical trial. Alzheimer’s Dement.2022;1-12. https://doi.org/10.1002/alz.12767 Recommendation: Vitamin, Mineral, and Multivitamin Supplementation to Prevent Cardiovascular Disease and Cancer: Preventive Medication | United States Preventive Services Taskforce https://www.uspreventiveservicestaskforce.org/uspstf/recommendation/vitamin-supplementation-to-prevent-cvd-and-cancer-preventive-medication Guest: Robert A. Baldor MD, FAAFP   Music Credit: Richard Onorato

Credits: 0.25 AMA PRA Category 1 Credit™   CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-328 Overview: Are you tired of sifting through conflicting information about nutrition and mortality? Look no further than this podcast episode, where we dive deep into the latest dietary research. With so much conjecture and small data sets out there, it can be challenging to know what advice to give. Tune in to this discussion to gain valuable insights and to make informed recommendations about healthy eating habits for your patients. Episode resource links: JAMA Intern Med. doi:10.1001/jamainternmed.2022.6117 Nutrients 2021 Jul 9;13(7):2342. doi: 10.3390/nu13072342. Guest: Robert A. Baldor MD, FAAFP   Music Credit: Richard Onorato

Credits: 0.25 AMA PRA Category 1 Credit™   CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-327 Overview: Congress has recently made changes to help fight the opioid epidemic and allow for an increase in access to treatment for opioid use disorder (OUD). Join us as we review these changes, and learn how you can use them to promote health equity in a clinical setting. Episode resource links: Hawk, K., Hoppe, J., Ketcham, E., LaPietra, A., Moulin, A., Nelson, L., ... & D’Onofrio, G. (2021). Consensus recommendations on the treatment of opioid use disorder in the emergency department. Annals of emergency medicine, 78(3), 434-442. Jones, K. F., O'Reilly-Jacob, M., & Tierney, M. (2022). Eliminating the buprenorphine DEA X waiver is critical to promote health equity. Nursing outlook, 70(1), 5-7. Jones, K. F. , Jacob, M. O. , Spetz, J. , Hailer, L. & Tierney, M.  (9000). Eliminate the buprenorphine DEA X waiver: Justification using a policy analysis approach.  Journal of Nursing Scholarship,  , doi: 10.1111/jnu.12871. Guest: Mariyan L. Montaque, DNP, FNP-BC Music Credit: Richard Onorato

Credits: 0.25 AMA PRA Category 1 Credit™   CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-326 Overview: Alcohol abuse has become more prevalent in the past decade, which means that primary care providers must play a crucial role in treating this preventable disorder. Don’t miss this discussion on the current state of alcohol abuse and how to use evidence-based screening tools for prevention. Episode resource links: Esser,M., Leung, G., Sherk, A., Bohm, M., Liu, Y., Lu, H. & Naimi, T.  Estimated Deaths Attributable to Excessive Alcohol Use Among US Adults Aged 20 to 64 Years, 2015 to 2019. JAMA Network Open. 2022;5(11):e2239485. doi:10.1001/jamanetworkopen.2022.39485 National Institute on Drug Abuse Screening and Assessment Tools Resource Chart: https://nida.nih.gov/nidamed-medical-health-professionals/screening-tools-resources/chart-screening-tools Substance Abuse and Mental Health Services Administration (SAMHSA):  National Help Line:  https://www.samhsa.gov/find-help/national-helpline Alcoholics Anonymous:  Find AA near you https://www.aa.org/find-aa Paradis, C., Butt, P., Shield, K., Poole, N., Wells, S., Naimi, T., Sherk, A., & the Low-Risk Alcohol Drinking Guidelines Scientific Expert Panels. (2023). Canada’s Guidance on Alcohol and Health: Final Report. Ottawa, Ont.: Canadian Centre on Substance Use and Addiction.  Fairbanks J, Umbreit A, Kolla BP, et al. Evidence-Based Pharmacotherapies for Alcohol Use Disorder: Clinical Pearls. Mayo Clin Proc. 2020;95(9):1964-1977. doi:10.1016/j.mayocp.2020.01.030 Guest: Jill M. Terrien PhD, ANP-BC   Music Credit: Richard Onorato

Credits: 0.25 AMA PRA Category 1 Credit™   CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-325 Overview: Obesity in children and adolescents is a complex and very often chronic condition. Besides encouraging healthy eating and increasing activity—both excellent behavioral measures—healthcare providers did not have a clear, evidence-based plan for managing this chronic condition until recently. In January, the AAP published its long-awaited new, evidence-based guidelines for the evaluation and treatment of children and adolescents with obesity. Greatly anticipated, it did, however, create some controversy. Please join us as we discuss the new guidelines, the evidence that it is based on, and how it may change practice.  Episode resource links: The American Academy of Pediatrics. Clinical Practice Guideline. S. E. Hampl. Clinical Practice Guideline for the Evaluation and Treatment of Children and Adolescents with Obesity. January 9, 2023.  Pediatrics e2022060640. https://doi.org/10.1542/peds.2022-060640 The American Academy of Pediatrics. S. E. Hampl. Executive Summary: Clinical Practice Guideline for the Evaluation and Treatment of Children and Adolescents with Obesity, January 9, 2023. Pediatrics e2022060641.https://doi.org/10.1542/peds.2022-060641;  https://publications.aap.org/pediatrics/article/doi/10.1542/peds.2022-060641/190440/Executive-Summary-Clinical-Practice-Guideline-for?autologincheck=redirected AAP News release https://www.aap.org/en/news-room/news-releases/aap/2022/american-academy-of-pediatrics-issues-its-first-comprehensive-guideline-on-evaluating-treating-children-and-adolescents-with-obesity/  The American Academy of Pediatrics Technical report; January 9, 2023. Appraisal of Clinical Care Practices for Child Obesity Treatment. Part I: Interventions. Pediatrics (2023) 151 (2): e2022060642.; https://doi.org/10.1542/peds.2022-060642 The American Academy of Pediatrics Technical report; January 9, 2023. Appraisal of Clinical Care Practices for Child Obesity Treatment. Part II: Comorbidities. Pediatrics (2023) 151 (2): e2022060643. https://doi.org/10.1542/peds.2022-060643   Guest: Susan Feeney, DNP, FNP-BC, NP-C   Music Credit: Richard Onorato

Credits: 0.25 AMA PRA Category 1 Credit™   CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-324 Overview: Parents who struggle with infant sleep problems may turn to primary care providers for guidance to help their child, but what are the evidence-based options? Hear what the experts have to say about the findings of a recent Journal of Pediatrics study of parents’ use of a variety of behavioral interventions for infant sleep problems.  Episode resource links: Implementation of Behavioral Interventions for Infant Sleep Problems in Real-World Settings: J Pediatr. November 11, 2022. https://doi.org/10.1016/j.jpeds.2022.10.038 Blunden, S. and Dawson, D. (2020), Behavioural sleep interventions in infants: Plan B – Combining models of responsiveness to increase parental choice. J Paediatr Child Health, 56: 675-679. https://doi.org/10.1111/jpc.14818 Guest: Robert A. Baldor MD, FAAFP   Music Credit: Richard Onorato

Credits: 0.25 AMA PRA Category 1 Credit™   CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-323 Overview: This episode will explore a common syndrome that is often misdiagnosed and underdiagnosed. Listen in as we discuss the cardinal symptoms and diagnostic criteria for postural orthostatic tachycardia syndrome (POTS) and learn about different management options, including the benefits of salt.  Episode resource links: Zha K, Brook J, McLaughlin A, Blitshteyn S. Gluten-free diet in postural orthostatic tachycardia syndrome (POTS). Chronic Illness. 2022;0(0). doi:10.1177/17423953221076984 Cooperrider, J., Kriegler, J., Yunus, S., & Wilson, R. (2022). A Survey-Based Study Examining Differences in Perception of Postural Orthostatic Tachycardia Syndrome Between Patients and Primary Care Physicians. Cureus, 14(10). Raj, S. R., Fedorowski, A., & Sheldon, R. S. (2022). Diagnosis and management of postural orthostatic tachycardia syndrome. Cmaj, 194(10), E378-E385. Williams, E. L., Raj, S. R., Schondorf, R., Shen, W. K., Wieling, W., & Claydon, V. E. (2022). Salt supplementation in the management of orthostatic intolerance: Vasovagal syncope and postural orthostatic tachycardia syndrome. Autonomic neuroscience, 237, 102906. Guest: Mariyan L. Montaque, DNP, FNP-BC   Music Credit: Richard Onorato

Credits: 0.25 AMA PRA Category 1 Credit™   CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-322 Overview: Patients deserve compassionate, safe, and effective pain management. But it’s important to remember that safe prescribing does not mean no prescribing. Join us as we discuss the 2022 CDC Clinical Practice Guidelines for prescribing opioids in the adult population. The updated and expanded guidelines can assist you in delivering patient-centered care for management of acute, subacute, and chronic pain. Episode resource links: Dowell D, Ragan KR, Jones CM, Baldwin GT, Chou R. CDC Clinical Practice Guideline for Prescribing Opioids for Pain —United States, 2022. MMWR Recomm Rep 2022;71(No. RR-3):1–95. DOI: http://dx.doi.org/10.15585/mmwr.rr7103a1 Dowell D, Haegerich TM, Chou R. CDC Guideline for Prescribing Opioids for Chronic Pain—United States, 2016. 2016;315(15):1624–1645. doi:10.1001/jama.2016.1464 Guest: Jill Terrien PhD, ANP-BC    Music Credit: Richard Onorato

Credits: 0.25 AMA PRA Category 1 Credit™   CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-321 Overview: Most perimenopausal and menopausal individuals will experience some symptoms. Up to 80% of women report some symptoms, with vasomotor symptoms being the most commonly reported; however, other symptoms such as sleep disturbance, sexual dysfunction, and mood can be present. These symptoms can have a tremendous negative impact on quality of life and well-being, yet many women remain untreated for their symptoms even though evidence-based treatments exist. Join us to discuss effective treatments and ways you can overcome barriers to providing evidence-based menopausal therapy. Episode resource links: DePree, Barbara MD, NCMP, MMM1; Houghton, Katherine MSc2; Shiozawa, Aki DrPH, MBA3; Esterberg, Elizabeth MS4; King, Deanna D. MS, PhD3; Kim, Janet PhD3; Mancuso, Shayna DO, FACOG3. Treatment and resource utilization for menopausal symptoms in the United States: a retrospective review of real-world evidence from US electronic health records. Menopause 30(1):p 70-79, January 2023. | DOI: 10.1097/GME.0000000000002095 https://journals.lww.com/menopausejournal/Fulltext/2023/01000/Treatment_and_resource_utilization_for_menopausal.11.aspx The North Amrican Menopause Society. (NAMS) The 2022 Hormone Therapy Position Statement of the North American Menopause Society. Menopause: The Journal of the North American Menopause Society. 29 (7)  pp 767-794. DOI: 10.1097/GME.0000000000002028 The North American Menopause Society (NAMS). Menopause Practice: A Clinician's Guide. 6th Pepper Pike, Ohio. September 2019.  Guest: Susan Feeney, DNP, FNP-BC, NP-C   Music Credit: Richard Onorato

Credits: 0.25 AMA PRA Category 1 Credit™   CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-320 Overview: New evidence points to the efficacy of a simple approach to managing and potentially curing generalized anxiety disorder. Join us to discuss this simple intervention and to review the diagnosis and treatment options for this prevalent disorder. Episode resource links: JAMA Psychiatry. 2023;80(1):13-21. doi:10.1001/jamapsychiatry.2022.3679 https://positivepsychology.com/mindfulness-based-stress-reduction-mbsr/ Guest: Susan Feeney, DNP, FNP-BC, NP-C   Music Credit: Richard Onorato 

Credits: 0.25 AMA PRA Category 1 Credit™   CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-319 Overview: In children, bacterial infections are a common cause of infectious conjunctivitis. But, like many clinicians, you may be uncertain about the efficacy of using antibiotic drops in these pediatric patients. Join us to get an evidence-based answer to the important question, “Are antibiotic drops needed in children with acute infectious conjunctivitis?” Episode resource links: Honkila M, Koskela U, Kontiokari T, et al. Effect of Topical Antibiotics on Duration of Acute Infective Conjunctivitis in Children: A Randomized Clinical Trial and a Systematic Review and Meta-analysis. JAMA Netw Open. 2022;5(10):e2234459. Published 2022 Oct 3. Guest: Alan M. Ehrlich, MD, FAAFP   Music Credit: Richard Onorato

Credits: 0.25 AMA PRA Category 1 Credit™   CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-318 Overview: Have you ever experienced impostor syndrome? Or do you mentor someone struggling with this sense of inadequacy? If so, you won’t want to miss this podcast episode. You will formulate a clear definition of impostor syndrome, understand its components, and walk away with practical tips to help overcome it... Episode resource links: J Am Coll Surg  2021 Nov;233(5):633-638. Curr Pharm Teach Learn 2022 Feb;14(2):130-132. doi: 10.1016/j.cptl.2021.11.019. Epub 2021 Dec 27 Guest: Mariyan L. Montaque, DNP, FNP-BC & Susan Feeney, DNP, FNP-BC, NP-C & Jill M. Terrien, PhD, ANP-BC   Music Credit: Richard Onorato To learn more about Primary Care Bootcamp for NPs and PAs: https://bootcamp.pri-med.com/app 

Credits: 0.25 AMA PRA Category 1 Credit™   CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-317 Overview: Exercise has been shown to be an effective way of decreasing migraine frequency, but the best type of exercise for this has not been established. A systematic review compared strength training to both high-intensity aerobic exercise and low-intensity aerobic exercise. Episode resource links: Woldeamanuel YW, Oliveira ABD. What is the efficacy of aerobic exercise versus strength training in the treatment of migraine? A systematic review and network meta-analysis of clinical trials. J Headache Pain. 2022;23(1):134. Published 2022 Oct 13. Guest: Alan M. Ehrlich, MD, FAAFP   Music Credit: Richard Onorato

Credits: 0.25 AMA PRA Category 1 Credit™   CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-316 Overview: While the benefits of proton pump inhibitors (PPIs) are widely known, the same cannot be said of the risks. These common medications are generally considered “safe,” but new data suggest the potential for long-term risks. Join us to discuss these long-term risks of PPI use and whether some of your patients should step down from PPIs to H2RAs.  Episode resource links: Gut : 28 September 2020. doi: 10.1136/gutjnl-2020-322557 Gut 2022 Jan; 71:16. (https://doi.org/10.1136/gutjnl-2021-325097) Front Pharmacol. 2022 Sep 14;13:979215. doi: 10.3389/fphar.2022.979215. eCollection 2022 Guest: Jill M. Terrien PhD, ANP-BC    Music Credit: Richard Onorato

Credits: 0.25 AMA PRA Category 1 Credit™   CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-315 Overview: A recent publication shows that being a “weekend warrior” exerciser provides the same benefit to mortality risk as spreading the physical activity out across the week. Listen to this podcast to hear the data from this study and to optimally counsel your patients on how to lower their mortality risk through physical activity. Episode resource links: Physical Activity Guidelines for Americans, 2nd Edition.; 2018. https://health.gov/paguidelines/second-edition/pdf/Physical_Activity_Guidelines_2nd_edition.pdf. dos Santos M, Ferrari G, Lee DH, et al. Association of the “Weekend Warrior” and Other Leisure-time Physical Activity Patterns With All-Cause and Cause-Specific Mortality: A Nationwide Cohort Study. JAMA Intern Med.2022;182(8):840–848. doi:10.1001/jamainternmed.2022.2488 Guest: Jillian Joseph, MPAS, PA-C   Music Credit: Richard Onorato

Credits: 0.25 AMA PRA Category 1 Credit™   CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-314 Overview: The herpes zoster virus, or shingles, is more than just a rash. Oftentimes we don’t consider the long-term risk of viruses, but we should. This episode focuses on the association between the herpes zoster virus and an increased risk of stroke. Join us to discuss data that show a reduction in stroke risk in individuals who receive the herpes zoster vaccine.  Episode resource links: Andrew N Bubak, Christina Coughlan, Janelle Posey, Anthony J Saviola, Christy S Niemeyer, Serena W R Lewis, Sara Bustos Lopez, Adriana Solano, Stephen K Tyring, Cassidy Delaney, Keith B Neeves, Ravi Mahalingam, Kirk C Hansen, Maria A Nagel, Zoster-Associated Prothrombotic Plasma Exosomes and Increased Stroke Risk, The Journal of Infectious Diseases, 2022;, jiac405, https://doi.org/10.1093/infdis/jiac405 https://www.idse.net/Review-Articles/Article/10-22/Immunization-Vaccine-Updates-Beyond-COVID-19/68244 https://www.cdc.gov/shingles/index.html https://familydoctor.org/condition/shingles/ Yang, Q., Chang, A., Tong, X., & Merritt, R. (2021). Herpes zoster vaccine live and risk of stroke among medicare beneficiaries: a population-based cohort study. Stroke, 52(5), 1712-1721. https://news.cuanschutz.edu/news-stories/researchers-reveal-why-shingles-can-cause-strokes Guest: Mariyan L. Montaque, DNP, FNP-BC   Music Credit: Richard Onorato

Credits: 0.25 AMA PRA Category 1 Credit™   CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-313 Overview: The prevalence of anxiety and depression has been increasing in US youth over the past decade with noted increases during the pandemic. The USPSTF recently released its recommendations supporting general screening for depression in 12- to 18-year-olds. Join us while we discuss the recommendations, the basis for these recommendations, how to integrate them into practice, and some strategies on how to support adolescents and families with a positive screen. Episode resource links: CDC Children’s Mental Health: https://www.cdc.gov/childrensmentalhealth/depression.html i. Data and Statistics on Children’s Mental Health https://www.cdc.gov/childrensmentalhealth/data.html Screening for Depression and Suicide Risk in Children and Adolescents - US Preventive Services Task Force Recommendations Statement; JAMA. doi:10.1001/jama.2022.16946. Published online October 11, 2022.  US Preventive Services Task Force Recommendation Statement on Depression and Suicide Risk in Children and Adolescents: Screening. https://www.uspreventiveservicestaskforce.org/uspstf/recommendation/screening-depression-suicide-risk-children-adolescents Guest: Susan Feeney, DNP, FNP-BC, NP-C   Music Credit: Richard Onorato

Credits: 0.25 AMA PRA Category 1 Credit™   CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-312 Overview: Brain training activities have been advocated to slow or prevent cognitive decline. Crossword puzzles can be cognitively demanding and have recently been shown to be superior to some of the brain training activities that have been promoted on apps and websites. Join us for discussion on how to counsel patients looking to improve their cognitive function. Episode resource links: Pillai JA, Hall CB, Dickson DW, Buschke H, Lipton RB, Verghese J. Association of crossword puzzle participation with memory decline in persons who develop dementia. J Int Neuropsychol Soc. 2011;17(6):1006-1013. Devanand DP et al. Computerized Games versus Crosswords Training in Mild Cognitive Impairment. NEJM Evidence October 27,2022 Guest: Alan M. Ehrlich, MD, FAAFP   Music Credit: Richard Onorato

Credits: 0.25 AMA PRA Category 1 Credit™   CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-311 Overview: Join us to discuss the results of a randomized controlled trial that evaluated the influence of increased dairy intake on fractures in older adults. Learn how this simple intervention can significantly mitigate the risk of falls and fractures in this vulnerable population. Episode resource links: BMJ 2021; 375 doi: https://doi.org/10.1136/bmj.n2364 Guest: Jill M. Terrien PhD, ANP-BC    Music Credit: Richard Onorato

Credits: 0.25 AMA PRA Category 1 Credit™   CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-310 Overview: Join us as we discuss the importance of assessing for sexual dysfunction in young women with a cancer diagnosis.  Episode resource links: Lena Wettergren, Lars E. Eriksson, Charlotta Bergström, Christel Hedman, Johan Ahlgren, Karin E. Smedby, Kristina Hellman, Roger Henriksson & Claudia Lampic (2022): Prevalence and risk factors for sexual dysfunction in young women following a cancer diagnosis – a population-based study, Acta Oncologica, DOI: 10.1080/0284186X.2022.2112283 https://doi.org/10.1080/0284186X.2022.2112283 Guest: Jill Terrien PhD, ANP-BC   Music Credit: Richard Onorato

Credits: 0.25 AMA PRA Category 1 Credit™   CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-309 Overview: Listen to this podcast to get answers to important questions about vitamin D supplementation in the first year of life. We will review a recent systematic review and meta-analysis on the relationship between vitamin D supplementation in the first year of life and outcomes, and we will discuss how these findings can be applied to your practice. Episode resource links: Nutrients; 2021 Feb 5;13(2):524. doi: 10.3390/nu13020524 Guest: Robert A. Baldor MD, FAAFP   Music Credit: Richard Onorato

Credits: 0.25 AMA PRA Category 1 Credit™   CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-308 Overview: In this episode, each podcaster will discuss the most impactful paper and podcast of the year. Episode resource links: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-302 https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-299 https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-289 https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-281 https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-275 https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-268 Guest: Alan Ehrlich MD, FAAFP, Jillian Joseph, MPAS, PA-C, Susan Feeney, DNP, FNP-BC, NP-C, Mariyan L. Montaque, DNP, FNP-BC, Jill M. Terrien PhD, ANP-BC    Music Credit: Richard Onorato

Credits: 0.25 AMA PRA Category 1 Credit™   CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-307 Overview: The COVID-19 epidemic resulted in overflowing ICUs and significant numbers of deaths among older adults. A recent study looked at the differences in outcomes between patients admitted with “No-code” vs “CPR” status and found no difference for high-risk individuals. Listen to this brief podcast to explore the data from this study and, in turn, give patients the information they need to make informed decisions regarding their desired code status on their advanced directives. Guest: Robert A. Baldor MD, FAAFP   Music Credit: Richard Onorato

Credits: 0.25 AMA PRA Category 1 Credit™   CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-306 Overview: In 2015, a landmark study, LEAP (Learning Early About Peanut Allergy), found that early introduction to peanuts, at 4 to 6 months, significantly reduced the incidence of peanut allergies in all children but especially in those at high risk for allergies. A recent survey of pediatric residents and attendings in a large academic center regarding knowledge and implementation of the guidelines uncovered a significant knowledge gap impacting the health of children. Join us as we discuss this gap and review the guidelines for preventing peanut allergies in infants and children.   Episode resource links: Sandhu S, Hanono M, Nagarajan S, Vastardi MA. Knowledge assessment of early peanut introduction in a New York City population [published online ahead of print, 2022 Jun 18]. Ann Allergy Asthma Immunol. 2022;S1081-1206(22)00534-8. doi:10.1016/j.anai.2022.06.013 Greer FR, Sicherer SH, Burks AW, AAP COMMITTEE ON NUTRITION, AAP SECTION ON ALLERGY AND IMMUNOLOGY. The Effects of Early Nutritional Interventions on the Development of Atopic Disease in Infants and Children: The Role of Maternal Dietary Restriction, Breastfeeding, Hydrolyzed Formulas, and Timing of Introduction of Allergenic Complementary Foods. Pediatrics. 2019;143(4): e20190281 Togias A, Cooper SF, Acebal ML, et al. Addendum guidelines for the prevention of peanut allergy in the United States: Report of the National Institute of Allergy and Infectious Diseases-sponsored expert panel. Ann Allergy Asthma Immunol. 2017;118(2):166-173.e7. doi:10.1016/j.anai.2016.10.004 Fleischer DM, Sicherer S, Greenhawt M, et al. Consensus Communication on Early Peanut Introduction and Prevention of Peanut Allergy in High-Risk Infants. Pediatr Dermatol. 2016;33(1):103-106. doi:10.1111/pde.12685 Du Toit, G., Roberts, G., Sayre, P. H., Bahnson, H. T., Radulovic, S., Santos, A. F., Brough, H. A., Phippard, D., Basting, M., Feeney, M., Turcanu, V., Sever, M. L., Gomez Lorenzo, M., Plaut, M., Lack, G., & LEAP Study Team (2015). Randomized trial of peanut consumption in infants at risk for peanut allergy. The New England journal of medicine, 372(9), 803–813. https://doi.org/10.1056/NEJMoa1414850 Koplin JJ, Soriano VX, Peters RL. Real-World LEAP Implementation. Curr Allergy Asthma Rep. 2021;22(6):61-66. doi:10.1007/s11882-022-01032-3 https://www.fda.gov/food/cfsan-constituent-updates/fda-completes-review-notification-regarding-health-claim-related-peanut-allergies Guest: Susan Feeney, DNP, FNP   Music Credit: Richard Onorato

Credits: 0.25 AMA PRA Category 1 Credit™   CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-305 Overview: We will review the general treatment approach to gastroesophageal reflux disease (GERD) and the risks of using proton pump inhibitors (PPI) for long durations. In particular, we will examine a new study that links PPI use, in comparison with H2 receptor antagonist (H2RA) use, with a significant increase in the risk of gastric cancer. This episode will highlight the importance of looking at PPIs on a medication review and evaluating whether patients are taking them for longer than needed.   Episode resource links: Abrahami D, McDonald EG, Schnitzer ME, et al. Proton pump inhibitors and risk of gastric cancer: population-based cohort study. Gut. 2022;71(1):16-24. Guest: Jillian Joseph, MPAS, PA-C   Music Credit: Richard Onorato

Credits: 0.25 AMA PRA Category 1 Credit™   CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-304 Overview: Pharmacogenomic testing has been suggested as a way to personalize medicine, particularly where the metabolism of medications can vary significantly. Unfortunately, despite increasing use of this testing, there has been little evidence showing a benefit in clinical outcomes. Listen to this podcast to explore the data on clinical outcomes for pharmacogenetic testing and how to best select medication for patients with depression. Episode resource links: Oslin DW, Lynch KG, Shih MC, et al. Effect of Pharmacogenomic Testing for Drug-Gene Interactions on Medication Selection and Remission of Symptoms in Major Depressive Disorder: The PRIME Care Randomized Clinical Trial. JAMA. 2022;328(2):151-161. Guest: Alan Ehrlich MD, FAAFP   Music Credit: Richard Onorato

Credits: 0.25 AMA PRA Category 1 Credit™   CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-303 Overview: Millions of Americans take Vitamin D supplementation to prevent a variety of illnesses, from COVID-19 and osteoporosis to heart disease and cancer. While most studies have failed to show a benefit in preventing COVID-19, heart disease, and cancer, the evidence has been mixed, at best, in showing benefits for preventing bone fractures. Despite this, vitamin D supplementation remains popular for fracture prevention. Join us to review a study published in the New England Journal of Medicine that failed to find any benefits for preventing fractures. Episode resource links: N Engl J Med 2022;387:299-309. DOI: 10.1056/NEJMoa2202106 Guest: Robert A. Baldor MD, FAAFP   Music Credit: Richard Onorato

Credits: 0.25 AMA PRA Category 1 Credit™     CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-302   Overview: Non-alcoholic fatty liver disease (NAFLD) is the most common chronic liver disease in the United States, with a prevalence rate of more than 30% of US adults. Most have not been diagnosed or treated. Join us to discuss the new AACE guidance on the diagnosis and treatment of NAFLD to reduce the burden of this common disease.   Episode resource links: AACE Guideline:  Endocrine Pract: May 2022, 28(5): 528-562 Coffee: Front Pharmacol. 2021 Dec 13;12:786596. doi: 10.3389/fphar.2021.786596   Guest: Robert A. Baldor, MD   Music Credit: Richard Onorato  

Credits: 0.25 AMA PRA Category 1 Credit™     CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-301   Overview: In this episode, we will discuss a simple and inexpensive yet effective strategy for slowing the loss of knee joint cartilage in a patient with osteoarthritis: walking. Hear how recent evidence suggests that including a walking regimen into treatment plans may confer numerous benefits in this patient population.   Episode resource links: Busse, JW, Sadeghirad, B., Oparin, Y. et al; Management of Acute Pain From Non–Low Back, Musculoskeletal Injuries: A Systematic Review and Network Meta-analysis of Randomized Trials. Ann Intern Med.2020;173:730-738. [Epub 18 August 2020]. doi:10.7326/M19-3601 Kolasinski, S.L., Neogi, T., Hochberg, M.C., Oatis, C., Guyatt, G., Block, J., Callahan, L., Copenhaver, C., Dodge, C., Felson, D., Gellar, K., Harvey, W.F., Hawker, G., Herzig, E., Kwoh, C.K., Nelson, A.E., Samuels, J., Scanzello, C., White, D., Wise, B., Altman, R.D., DiRenzo, D., Fontanarosa, J., Giradi, G., Ishimori, M., Misra, D., Shah, A.A., Shmagel, A.K., Thoma, L.M., Turgunbaev, M., Turner, A.S. and Reston, J. (2020), 2019 American College of Rheumatology/Arthritis Foundation Guideline for the Management of Osteoarthritis of the Hand, Hip, and Knee. Arthritis Care Res, 72: 149-162. https://doi.org/10.1002/acr.24131 Lo GH, Vinod S, Richard MJ, et al. Association Between Walking for Exercise and Symptomatic and Structural Progression in Individuals with Knee Osteoarthritis: Data from the Osteoarthritis Initiative Cohort [published online ahead of print, 2022 Jun 8]. Arthritis Rheumatol. 2022;10.1002/art.42241. doi:10.1002/art.42241 Thudium C. Markers of synovial inflammation matrix turnover and symptoms. Presented at: OARSI 2022 World Congress on Osteoarthritis; April 7-10; Berlin, Germany (virtual meeting). Ooman JMH. Babs on a mission: An experimental study on the effects of message framing and exemplification on treatment intentions of osteoarthritis patients. Presented at: OARSI 2022 World Congress on Osteoarthritis; April 7-10; Berlin, Germany (virtual meeting). Zeng C, Doherty M, Persson MSM, et al. Comparative efficacy and safety of acetaminophen, topical and oral non-steroidal anti-inflammatory drugs for knee osteoarthritis: evidence from a network meta-analysis of randomized controlled trials and real-world data. Osteoarthritis Cartilage. 2021;29(9):1242-1251. doi:10.1016/j.joca.2021.06.004   Guest: Susan Feeney, DNP, FNP-BC, NP-C   Music Credit: Richard Onorato  

Credits: 0.25 AMA PRA Category 1 Credit™     CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-300   Overview: Most primary care clinicians are unaware of a possible association between childhood cat ownership and adult psychosis. Join us to hear the results of a recent retrospective study that suggests this link. Hear practical tips to share with patients who own an outdoor cat to help them avoid the toxoplasmosis that may be a potential etiologic agent for psychiatric illness.   Episode resource links: Journal of Psychiatric Research. Volume 148, April 2022, Pages 197-203 doi.org/10.1016/j.jpsychires.2022.01.058   Guest: Robert A. Baldor, MD   Music Credit: Richard Onorato  

Credits: 0.25 AMA PRA Category 1 Credit™   CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-299 Overview: Polypharmacy is a burden on patients with dementia. Adverse drug reactions, side effects, the cost, and inappropriate medications that may lead to falls and morbidity/mortality may be conferring more harm than benefit. Unfortunately, 44% of men and 57% of women >65 years take five or more nonprescription and/or prescription medications per day. Join us as we discuss methods for deprescribing polypharmacy in this patient population.  Episode resource links: Growdon, M. E., Gan, S., Yaffe, K., & Steinman, M. A. (2021). Polypharmacy among older adults with dementia compared with those without dementia in the United States. Journal of the American Geriatrics Society, 69(9), 2464–2475. PMID: 34101822 https://doi.org/10.1111/jgs.17291 Narayan, S. W., & Nishtala, P. S. (2017). Discontinuation of Preventive Medicines in Older People with Limited Life Expectancy: A Systematic Review. Drugs & aging, 34(10), 767–776. PMID: 28853000  https://doi.org/10.1007/s40266-017-0487-1 Guest: Jill M. Terrien PhD, ANP-BC    Music Credit: Richard Onorato  

Credits: 0.25 AMA PRA Category 1 Credit™   CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-298 Overview: :  Lower respiratory tract infections are a common presentation in children, and many of those children receive antibiotic prescriptions. Join us for this episode to review evidence that supports avoiding such treatment unless pneumonia or other bacterial infections are suspected. Episode resource links: Little P, Francis NA, Stuart B, et al. Antibiotics for lower respiratory tract infection in children presenting in primary care in England (ARTIC PC): a double-blind, randomised, placebo-controlled trial. Lancet. 2021;398(10309):1417-1426 Guest: Jillian Joseph, MSPAS, PA-C   Music Credit: Richard Onorato

Credits: 0.25 AMA PRA Category 1 Credit™   CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-297   Overview: The efficacy of probiotic formulations in the prevention of antibiotic-associated diarrhea remains unclear. Join us to review a recent study in JAMA Pediatrics that attempts to answer this question.   Episode resource links: Multispecies Probiotic for the Prevention of Antibiotic-Associated Diarrhea in Children A Randomized Clinical Trial   Guest: Robert A. Baldor, MD   Music Credit: Richard Onorato

Credits: 0.25 AMA PRA Category 1 Credit™   CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-296   Overview: The number of drug overdoses in the United States continues to rise in tandem with the growing opioid epidemic. In 2020, nearly 92,000 people died from drug overdoses in the United States, which was an approximate 31% increase in just one year. This episode will highlight perceived barriers to harm reduction and show primary care providers how they can play a key role in overdose prevention.    Episode resource links: https://www.cdc.gov/opioids/overdoseprevention/reverse-od.html https://www.cdc.gov/drugoverdose/deaths/index.html#:~:text=Drug%20Overdose%20Deaths%20Remain%20High&text=Opioids%E2%80%94mainly%20synthetic%20opioids%20(other,of%20all%20drug%20overdose%20deaths). Bonner, L. (2022). As the opioid epidemic takes a turn for the worse, do we need more potent forms of naloxone?. Pharmacy Today, 28(3), 26. Messmer, S., & Jarrett, J. (2022). When Naloxone Isn’t Enough. New England Journal of Medicine. Tse, W. C., Djordjevic, F., Borja, V., Picco, L., Lam, T., Olsen, A., ... & Nielsen, S. (2022). Does naloxone provision lead to increased substance use? A systematic review to assess if there is evidence of a ‘moral hazard’associated with naloxone supply. International Journal of Drug Policy, 100, 103513.   Guest: Mariyan L. Montaque, DNP, FNP-BC   Music Credit: Richard Onorato

Credits: 0.25 AMA PRA Category 1 Credit™   CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-295   Overview: Chronic obstructive pulmonary disease (COPD) is typically diagnosed based on spirometry findings, but what if that finding isn’t what you expect? Spirometry measurements are compared to standard values for age, sex, and race. The use of race-based equations has been questioned in several clinical situations, and researchers are now raising similar concerns about the use of race-based equations in spirometry, which may lead to health inequities. Join us for an important discussion on how to overcome these potential disparities in diagnosing COPD.   Episode resource links: Liu GY, Khan SS, Colangelo LA, et al. Comparing Racial Differences in Emphysema Prevalence Among Adults With Normal Spirometry: A Secondary Data Analysis of the CARDIA Lung Study [published online ahead of print, 2022 Jul 19]. Ann Intern Med. 2022;10.7326/M22-0205.   Guest: Alan Ehrlich MD, FAAFP   Music Credit: Richard Onorato

Credits: 0.25 AMA PRA Category 1 Credit™   CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-294   Overview: Fibromyalgia is a common and difficult to diagnose disease, with highly subjective symptoms. Another challenge is that treatment is dependent on a patient’s implementation lifestyle changes. This brief podcast walks you through the diagnosis of fibromyalgia and offers best evidence on effective treatments.   Episode resource links: Mediations:  JAMA Netw Open. 2022;5(5):e2212939 Acupuncture:  J Pain Res. 2022; 15: 315–329   Guest: Susan Feeney, DNP, FNP-BC, NP-C   Music Credit: Richard Onorato

Credits: 0.25 AMA PRA Category 1 Credit™   CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-293   Overview: Evidence informs us that almost one-third of antibiotic prescriptions written for children in the United States are inappropriate, meaning they are not in line with evidence-based guidelines. Antibiotics are tremendous tools and beneficial when used appropriately; however, as with all pharmacological therapy, there are risks of adverse effects and healthcare cost. When prescribed inappropriately, they unnecessarily put children at risk and cause financial burden on individuals and the system. Please join the podcast team as we discuss recent evidence on these risks and burden and consider how this evidence can help improve practice.    Episode resource links: Butler AM, Brown DS, Durkin MJ, et al. Association of Inappropriate Outpatient Pediatric Antibiotic Prescriptions With Adverse Drug Events and Health Care Expenditures. JAMA Netw Open.2022;5(5):e2214153. doi:10.1001/jamanetworkopen.2022.14153   Guest: Susan Feeney, DNP, FNP-BC, NP-C   Music Credit: Richard Onorato

Credits: 0.25 AMA PRA Category 1 Credit™   CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-292   Overview: Alcohol use disorder is common, but effective medications to treat this disorder are not widely prescribed in the outpatient primary care setting, despite being available and having relatively good formulary coverage. Join us to hear how the use of medical treatment can decrease the incidence and progression of alcohol-associated liver disease.   Episode resource links: Augustin G. L. Vannier et al, Incidence and Progression of Alcohol-Associated Liver Disease After Medical Therapy for Alcohol Use Disorder, JAMA Network Open (2022).  DOI: 10.1001/jamanetworkopen.2022.13014   Tetreault JM, O'Connor PG. Risky drinking and alcohol use disorder: Epidemiology, pathogenesis, clinical manifestations, course, assessment, and diagnosis. UpToDate. Published April 28, 2022. Accessed June 11, 2022.    Holt SR, Tetrault, JM. Ambulatory Management of alcohol withdrawal. UpToDate. Published May 19, 2022. Accessed June 11, 2022.   Holt SR. Approach to treating alcohol use disorder. UpToDate. Published March 22, 2022. Accessed June 11, 2022.   Guest: Jillian Joseph, MSPAS, PA-C   Music Credit: Richard Onorato

Credits: 0.25 AMA PRA Category 1 Credit™   CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-291   Overview: Concerns have been raised over guideline recommendations for lowering systolic blood pressure (BP) to 60 years. To achieve such targets often requires intensive BP treatments, which can result in harms from syncope or falls. Join us to review the results of a recently published meta-analysis done to estimate the time needed to potentially derive clinical benefit from such BP treatments in patients 60 years and older.    Episode resource links: JAMA Intern Med. 2022;182(6):660-667. doi:10.1001/jamainternmed.2022.1657   Guest: Robert A. Baldor, MD   Music Credit: Richard Onorato

Credits: 0.25 AMA PRA Category 1 Credit™   CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-290   Overview: This brief podcast discusses the prevalence of egg and nut allergies in children, how to lower the risk of developing these allergies, and which patients are at greatest risk. Hear how to best counsel parents about their child’s allergies and help them anticipate their child’s future health.   Episode resource links: The natural history of peanut and egg allergy in children up to age 6 years in the HealthNuts population-based longitudinal study; Am Aca Allergy, Asthma & Immunol 2022; https://doi.org/10.1016/j.jaci.2022.04.008 Dietary Interventions to pRevent Atopic Disease in Children, AAP 3/19: https://publications.aap.org/aapnews/news/8699   Guest: Jill M. Terrien PhD, ANP-BC   Music Credit: Richard Onorato

Credits: 0.25 AMA PRA Category 1 Credit™   CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-289 Overview: Excessive screen time has been associated with numerous adverse health outcomes. Join us for a look at a fascinating new study that explores how limiting screen time can increase physical activity in children. Listen to this brief podcast before you counsel your next patient on how screen time can affect their children’s (and their) health. Episode resource links: Pedersen J,et al. Effects of Limiting Recreational Screen Media Use on Physical Activity and Sleep in Families With Children: A Cluster Randomized Clinical Trial. JAMA Pediatr. 2022 May 23:e221519 Screen Time and Children. American Academy of Child and Adolescent Psychiatry: https://www.aacap.org/AACAP/Families_and_Youth/Facts_for_Families/FFF-Guide/Children-And-Watching-TV-054.aspx Guest: Alan Ehrlich MD, FAAFP Music Credit: Richard Onorato

Credits: 0.25 AMA PRA Category 1 Credit™   CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-288 Overview: Coffee is one of the most consumed beverages worldwide. An estimated 500 million cups are consumed per day in the United States. As testimony to this, count the number of coffee shops available—most with drive-through access—the next time you are out for a drive. A growing body of evidence indicates that moderate coffee consumption (2-3 cups per day) is associated with reduction in all-cause mortality. What hasn’t been looked at closely is the effect of coffee with sugar and artificial sweeteners on these measures. Join us while we discuss recent evidence regarding consumption of coffee—with or without sweeteners—and its association with all-cause mortality. Episode resource links: Liu D, Li ZH, Shen D, Zhang PD, Song WQ, Zhang WT, Huang QM, Chen PL, Zhang XR, Mao C. Association of Sugar-Sweetened, Artificially Sweetened, and Unsweetened Coffee Consumption With All-Cause and Cause-Specific Mortality : A Large Prospective Cohort Study. Ann Intern Med. 2022 May 31. doi: 10.7326/M21-2977. Epub ahead of print. PMID: 35635846. Wee CC. The Potential Health Benefit of Coffee: Does a Spoonful of Sugar Make It All Go Away? Ann Intern Med. 2022 May 31. doi: 10.7326/M22-1465. Epub ahead of print. PMID: 35635845. Guest: Susan Feeney, DNP, FNP Music Credit: Richard Onorato

Credits: 0.25 AMA PRA Category 1 Credit™   CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-287 Overview: Join us to discuss the rates of false positives in mammography and how to decrease them. Specifically, this session reviews data from an observational comparative effectiveness study suggesting that the type of mammography, interval, and other factors can affect the probability of false positive results.  Episode resource links: Ho TH, Bissell MCS, Kerlikowske K, et al. Cumulative Probability of False-Positive Results After 10 Years of Screening With Digital Breast Tomosynthesis vs Digital Mammography. JAMA Netw Open. 2022;5(3):e222440. doi:10.1001/jamanetworkopen.2022.2440 Breast Cancer Screening Guidelines for Women (CDC Chart)—Last reviewed 9-2020 chrome-extension://efaidnbmnnnibpcajpcglclefindmkaj/https://www.cdc.gov/cancer/breast/pdf/breast-cancer-screening-guidelines-508.pdf Canelo-Aybar, C., Posso, M., Montero, N. et al. Benefits and harms of annual, biennial, or triennial breast cancer mammography screening for women at average risk of breast cancer: a systematic review for the European Commission Initiative on Breast Cancer (ECIBC). Br J Cancer 126, 673–688 (2022). https://doi.org/10.1038/s41416-021-01521-8 Guest: Jill M. Terrien PhD, ANP-BC    Music Credit: Richard Onorato

Credits: 0.25 AMA PRA Category 1 Credit™   CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-286 Overview: The controversy surrounding whether to prescribe aspirin for primary prevention of cardiovascular disease in adult patients has left many clinicians unsure of the right approach. In this podcast, we’ll review the latest USPSTF recommendation on this topic and dig into the evidence behind the recommendation. Episode resource links: JAMA. 2022;327(16):1577-1584. doi:10.1001/jama.2022.4983 Guest: Robert A. Baldor MD, FAAFP   Music Credit: Richard Onorato

Credits: 0.25 AMA PRA Category 1 Credit™   CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-285 Overview: Join us for a closer look at tirzepatide, a first-in-class glucose-dependent insulinotropic peptide (GIP) and a glucagon-like peptide-1 receptor agonist (GLP-1 RA). See how this novel glucose-lowering agent can help raise the bar in both HbA1c lowering and weight loss in patients with type 2 diabetes mellitus. Episode resource links: Karagiannis T, Avgerinos I, Liakos A, Del Prato S, Matthews DR, Tsapas A, Bekiari E. Management of type 2 diabetes with the dual GIP/GLP-1 receptor agonist tirzepatide: a systematic review and meta-analysis. Diabetologia. 2022 May 17:1–11. Guest: Alan Ehrlich MD, FAAFP   Music Credit: Richard Onorato

Credits: 0.25 AMA PRA Category 1 Credit™   CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-284 Overview: Most primary care clinicians treating patients with male androgenetic alopecia are unfamiliar with studies looking at off-label use of medications for this condition. In this episode, you will hear a review of an important recent meta-analysis published in JAMA Dermatology that highlights the efficacy of commonly used agents to treat this condition. Episode resource links: JAMA Dermatol. doi:10.1001/jamadermatol.2021.5743 Guest: Robert A. Baldor MD, FAAFP   Music Credit: Richard Onorato

Credits: 0.25 AMA PRA Category 1 Credit™   CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-283 Overview: Listen to this podcast to hear a simple method to help those with COPD improve their symptom control and lower exacerbation rates.  Episode resource links: Am J Respir Crit Care Med Vol 205, Iss 4, pp 421–430, Feb 15, 2022 Guest: Jillian Joseph, MSPAS, PA-C   Music Credit: Richard Onorato